Cardiovascular Biology
Researchers in this group use state-of-the-art technologies to study normal and abnormal cardiac and vascular function and development in animal model systems and human subjects. A wide variety of experimental approaches are used to identify molecular signals and cellular processes involved in cardiovascular development and disease.
Through a greater understanding of molecular mechanisms, researchers hope to understand and find ways to treat congenital malformations and cardiovascular disease.
Faculty
Jay Degen, PhD, Professor
The role of hemostatic factors and coupled signaling systems in development, inflammatory response, vessel wall disease and tumor biology [Visit Experimental Hematology and Cancer Biology]
Robert B. Hinton, JR, MD, Assistant Professor
Cardiovascular genetics and cardiac development [Visit Molecular and Cardiovascular Biology]
Richard Lang, PhD, Professor
Eye development with an emphasis on lens induction and vascular patterning [Visit the Lang Lab]
Tim Le Cras, PhD, Associate Professor
Chronic lung diseases: Asthma, Bronchopulmonary dysplasia, Pulmonary fibrosis, Pulmonary hypertension [Visit the Le Cras Lab]
Jeffery D. Molkentin, PhD, Professor
Transcriptional control of cardiac development and the molecular signaling pathways involved in cardiac hypertrophy [Visit the Molkentin Lab]
Jeffrey Robbins, PhD, Professor
Molecular basis of heart performance and structure-function characteristics of cardiac contractile proteins related to hypertrophic myopathies [Visit the Robbins Lab]
Arnold W. Strauss, MD, Chair Department of Pediatric and Director of Cincinnati Children's Research Foundation
Molecular basis of disorders of mitochondrial fatty acid oxidation and the genetic causes of congenital heart disease and cardiomyopathies [Visit the Strauss Lab]
Saulius Sumanas, PhD, Assistant Professor
Molecular mechanisms of the embryonic vasculature formation [Visit the Sumanas Lab]
Stephanie Ware, MD, PhD, Associate Professor
Genetics of cardiovascular development [Visit the Ware Lab]
Joshua Waxman, PhD, Assistant Professor
Molecular mechanisms of organogenesis. Regulation of signaling pathways that determine cardiac cell formation [Visit the Waxman Lab]
David Wieczorek, PhD, Professor
Professor, Analysis of protein expression in normal and diseased cardiac and skeletal muscle [Visit the Wieczorek Lab]
Katherine Yutzey, PhD, Professor
Morphogenesis of the heart and transcriptional regulatory networks involved in cardiac determination and differentiation; congenital heart disease [Visit the Yutzey Lab]
Contact Us
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
