Genetics and Gene Therapy
Researchers at Cincinnati Children's apply molecular technologies to the elucidation of disease mechanisms, and to the development of treatment for heritable diseases and inherited disease susceptibilities.
Gene Therapy research focuses on developing and improving gene transfer technology to treat childhood diseases at the genetic level.
Faculty
Zubair M. Ahmed, PhD, Assistant Professor
Identification and functional analysis of genes essential for normal visual and auditory perceptions in humans [Visit the Ahmed Lab]
Paul Andreassen, PhD, Assistant Professor
Fanconi anemia and breast cancer susceptibility proteins in DNA damage responses and genetic stability [Visit the Andreassen lab]
Artem Barski, PhD, Assistant Professor
Epigenomics of immunological memory [Visit Allergy and Immunology]
Chieh Chang, PhD, Assistant Professor
Molecular mechanisms underlying axon growth and regeneration and age-dependent decline in neuronal plasticity [Visit the Chang Lab]
Jay Degen, PhD, Professor
The role of hemostatic factors and coupled signaling systems in development, inflammatory response, vessel wall disease and tumor biology [Visit Experimental Hematology and Cancer Biology]
John Harley, MD, PhD, Professor
Lupus genetics, genetics and genomics [Visit Rheumatology]
Rashmi Hegde, PhD, Professor
Structural biology of proteins in embryonic cellfate determination, and proteins involved in the life- and infection-cycles of the cancer-associated papillomaviruses [Visit the Hegde Lab]
Gurjit Hershey, MD, PhD, Professor
Genetics and the pathogenesis of atopic disorders [Visit Asthma Research]
Robert B. Hinton, Jr, MD, Assistant Professor
Cardiovascular genetics and cardiac development [Visit Molecular and Cardiovascular Biology]
Rulang Jiang, PhD, Professor
Genetic basis and developmental mechanisms of structural birth defects [Visit the Jiang Lab]
Tanya V. Kalin, MD, PhD, Assistant Professor
Transcriptional regulation of DNA replication and mitosis in tumor cells in vitro and in vivo; diagnostic, prevention and treatment of lung and prostate cancers. [Visit the Kalin Lab]
Louis Muglia, MD, PhD, Professor
Genetic and developmental mechanisms controlling the timing of birth and risk of preterm birth; molecular genetic analysis of the behavioral and neuroendocrine responses to stress. [Visit the Muglia Lab]
Nancy Ratner, PhD, Professor
The peripheral nerve in development and disease [Visit the Ratner Lab]
Saima Riazuddin, PhD, Assistant Professor
Genetic and molecular basis of recessively inherited hearing impairment utilizing human subjects and mutant mouse models. [Visit the Riazuddin Lab]
Rolf Stottmann, PhD, Assistant Professor
Neuronal specification and migration [Visit Human Genetics]
Arnold W. Strauss, MD, Chair Department of Pediatrics and Director of Cincinnati Children's Research Foundation
Molecular basis of disorders of mitochondrial fatty acid oxidation and the genetic causes of congenital heart disease and cardiomyopathies [Visit the Strauss Lab]
Stephanie Ware, MD, PhD, Associate Professor
Genetics of cardiovascular development [Visit the Ware Lab]
Joshua Waxman, PhD, Assistant Professor
Molecular mechanisms of organogenesis. Regulation of signaling pathways that determine cardiac cell formation [Visit the Waxman Lab]
Timothy E. Weaver, PhD, Professor
Protein misfolding and chronic lung disease [Visit the Weaver Lab]
Susanne Wells, PhD, Associate Professor
Papilloma virus and cervical cancer [Visit the Susanne Wells Lab]
David Wieczorek, PhD, Professor
Professor, Analysis of protein expression in normal and diseased cardiac and skeletal muscle [Visit the Wieczorek Lab]
Christopher Wylie, PhD, Professor
(1) Control of the cytoskeleton, control of cell migration and control of early cell lineage specification, in vertebrate embryos (2) Control of gonad formation, primordial germ cell migration, oocyte maturation and egg formation [Visit the Wylie-Heasman Lab]
Chunyue Yin, PhD, Assistant Professor
The molecular and cellular mechanisms underlying liver development and disease pathogenesis using the zebrafish model organism. [Visit the Yin Lab]
Contact Us
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
