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The dramatic changes in lifestyle and dietary trends have triggered a rapid, worldwide epidemic of chronic metabolic diseases, including obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. Despite its enormous impact on global public health, the mechanisms underlying this cluster of pathologies are still unclear, and effective preventive and/or therapeutic strategies are limited.
Research in this group focuses on understanding the molecular mechanisms of cellular, tissue, and systemic metabolisms and how their abnormalities result in metabolic diseases. We hope to develop novel therapeutic strategies in the prevention of metabolic diseases.
Biplab DasGupta, PhD, Assistant ProfessorNeural stem cells, cancer stem cells, brain cancer and brain development [Visit the Dasgupta Lab]
Takahisa Nakamura, PhD, Assistant ProfessorMolecular mechanism of obesity-induced metabolic diseases.[Visit Endocrinology]
Jim Wells, PhD, Associate Professor Endoderm organogenesis and promoting the differentiation of embryonic stem cells into therapeutic endoderm derivatives. [Visit the Wells Lab]
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