Molecular Embryology
Research in this area focuses on the structural, biochemical, molecular, genetic and cellular mechanisms that govern cell behavior and pattern formation during embryonic development. Model organisms used in these studies include fly, fish, frog, and mouse.
A deeper understanding of how organisms are made and how environmental and genetic perturbations can result in birth defects will lead to our improved ability to regenerate and repair organs damaged by disease, trauma or congenital defects.
Faculty
Samantha Brugmann, PhD, Assistant Professor
We are interested in craniofacial development and the etiology of craniofacial disorders. [Visit Plastic Surgery]
Kenneth Campbell, PhD, Professor
Cellular and molecular control of vertebrate forebrain development [Visit Developmental Biology]
Chieh Chang, PhD, Assistant Professor
Molecular mechanisms underlying axon growth and regeneration and age-dependent decline in neuronal plasticity [Visit the Chang Lab]
Tiffany Cook, PhD, Associate Professor
Molecular basis of eye development [Visit the Cook Lab]
Brian Gebelein, PhD, Assistant Professor
Patterning of the nervous and digestive systems during development [Visit the Gebelein Lab]
Rashmi Hegde, PhD, Professor
Structural biology of proteins in embryonic cellfate determination, and proteins involved in the life- and infection-cycles of the cancer-associated papillomaviruses [Visit the Hegde Lab]
Stacey S. Huppert, PhD, Associate Professor
Intercellular signaling pathways that regulate the patterning of liver architecture during development and regeneration. [Visit the Huppert Lab]
Rulang Jiang, PhD, Professor
Genetic basis and developmental mechanisms of structural birth defects [Visit the Jiang Lab]
Tim Le Cras, PhD, Associate Professor
Chronic lung diseases: Asthma, Bronchopulmonary dysplasia, Pulmonary fibrosis, Pulmonary hypertension [Visit the Le Cras Lab]
Jun Ma, PhD, Associate Professor
Molecular mechanisms of transcriptional regulation and development using yeast and Drosophila as model systems [Visit Biomedical Informatics]
Yuya Ogawa, PhD
Molecular mechanisms of long noncoding RNA-mediated epigenetic gene regulation during mammalian development; X-chromosome inactivation using ex vivo differentiation system with mouse ES cells. [Visit Reproductive Sciences]
Steven Potter, PhD, Professor
Studies of homeobox genes that control mammalian development using gene targeting and transgenic mice [Visit the Potter Lab]
John Shannon, PhD, Professor
Lung developmental biology; lung cell biology; surfactant protein gene expression [Visit Pulmonary Biology]
Rolf Stottmann, PhD, Assistant Professor
Neuronal specification and migration [Visit Human Genetics]
Saulius Sumanas, PhD
Molecular mechanisms of the embryonic vasculature formation [Visit the Sumanas Lab]
Ronald R. Waclaw, MS, PhD, Assistant Professor
Development of forebrain progenitor cells that contribute to the postnatal “neurogenic” niche in the subventricular zone [Visit Experimental Hematology and Cancer Biology]
Susan Waltz, PhD, Assistant Professor
Molecular analysis of growth factors and receptor tyrosine kinases in tumorigenesis, organ function, and cellular trauma [Visit the Waltz Lab]
Stephanie Ware, MD, PhD, Associate Professor
Genetics of cardiovascular development [Visit the Ware Lab]
Joshua Waxman, PhD, Assistant Professor
Molecular mechanisms of organogenesis. Regulation of signaling pathways that determine cardiac cell formation [Visit the Waxman Lab]
Jim Wells, PhD, Assistant Professor
Endoderm organogenesis and promoting the differentiation of embryonic stem cells into therapeutic endoderm derivatives. [Visit the Jim Wells Lab]
Christopher Wylie, PhD, Professor
(1) Control of the cytoskeleton, control of cell migration and control of early cell lineage specification, in vertebrate embryos (2) Control of gonad formation, primordial germ cell migration, oocyte maturation and egg formation [Visit the Wylie-Heasman Lab]
Katherine Yutzey, PhD, Professor
Morphogenesis of the heart and transcriptional regulatory networks involved in cardiac determination and differentiation; congenital heart disease [Visit the Yutzey Lab]
Aaron Zorn, PhD, Associate Professor
Molecular mechanisms of endoderm organ development [Visit the Zorn Lab]
Contact Us
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
