Molecular and Developmental Biology Graduate Program

  • Development of Other Organ Systems

    Musculoskeletal | Kidney | Urogenital | Ear | Skin

    The research in these areas focuses on understanding the normal development of organs and how abnormal development results in childhood disease.

    There are many organ systems affected by pediatric disease. The Cincinnati Children's Hospital Research Foundation has initiated a 7 year expansion project that includes a new state-of-the-art research building and a commitment to hire 19 new faculty members to expand our research into the development and disease of other organ systems.

    Faculty

    Zubair M. Ahmed, PhD, Assistant Professor
    Identification and functional analysis of genes essential for normal visual and auditory perceptions in humans [Visit the Ahmed Lab]

    Min-Xin Guan, PhD, Associate Professor
    Mitochondrial biogenesis, cellular and molecular biology of mitochondrial disorders, especially in hearing loss, blindness and neuromuscular disorders [Visit the Ear and Hearing Center]

    John Harley, MD, PhD, Professor
    Lupus genetics, genetics and genomics [Visit Rheumatology]

    David Hildeman, PhD, Associate Professor
    Molecular biology of antigen-specific T cells, including mechanisms involved in cell signaling, apoptosis, and sex-based differences in autoimmunity and the T cell response to viral infections [Visit Immunobiology]

    Rulang Jiang, PhD, Professor
    Genetic basis and developmental mechanisms of structural birth defects [Visit the Jiang Lab]

    Jun Ma, PhD, Associate Professor
    Molecular mechanisms of transcriptional regulation and development using yeast and Drosophila as model systems [Visit Biomedical Informatics]

    Joo-Seop Park, PhD, Assistant Professor
    Gene regulatory networks underlying organogenesis and disease, Kidney development. [Visit Urology]

    Sarah Pixley, PhD, Associate Professor
    Neurogenesis and neurotrophic interactions in olfactory neuron cultures and in vivo; neuronal stem cells [Visit the Pixley Lab]

    Steven Potter, PhD, Professor
    Studies of homeobox genes that control mammalian development using gene targeting and transgenic mice [Visit the Potter Lab]

    Saima Riazuddin, PhD, Assistant Professor
    Genetic and molecular basis of recessively inherited hearing impairment utilizing human subjects and mutant mouse models. [Visit the Riazuddin Lab]

    Rolf Stottmann, PhD, Assistant Professor
    Neuronal specification and migration [Visit Human Genetics]

    Charles Vorhees, PhD, Professor
    (1) Determine the mechanism of action of substituted amphetamines on brain development and (2) use of gene targeting to determine how deletion of specific brain proteins affect learning and memory [Visit the Vorhees Lab]

    Susan Waltz, PhD, Assistant Professor
    Molecular analysis of growth factors and receptor tyrosine kinases in tumorigenesis, organ function, and cellular trauma 

    Joshua Waxman, PhD, Assistant Professor
    Molecular mechanisms of organogenesis. Regulation of signaling pathways that determine cardiac cell formation [Visit the Waxman Lab]

    Contact Us

    For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.

 
  • Diseases of Other Organ Systems

    Development of other organ systems.
    • Birth defects
    • Congenital cytomegalovirus infection
    • Congenital deafness
    • Congenital malformations of the ear
    • Deafness
    • Hearing loss
    • Heterotaxy
    • Hollow visceral
    • Neuromuscular disorders
    • Obesity

    View a complete list of the diseases that our students and faculty are fighting.