Molecular and Developmental Biology Graduate Program

  • Reproductive Biology

    Other research includes the etiology of germ cell tumors, which are one of the most common tumors arising in children.Research in these areas include:

    • The basis of genetic or drug-induced congenital malformations, attempting to prevent birth defects in some of the 150,000 afflicted babies born each year.
    • The processes of gametogenesis, egg maturation, embryo implantation, and gonad development, cellular processes that are prime targets for new contraceptive methods and infertility treatments. Other research includes the etiology of germ cell tumors, which are one of the most common tumors arising in children.

    Faculty

    Tony De Falco, PhD.Tony De Falco, PhD, Assistant Professor
    The De Falco lab is interested in uncovering the mechanisms underlying the differentiation of the fetal gonad, focusing on how myeloid cells (such as macrophages) and vasculature promote tissue remodeling during organogenesis. Additionally, we are investigating the roles of myeloid cells in regulating spermatogonial stem cell differentiation in the adult testis. [Visit the De Falco Lab]

    Sudhansu K. Dey, PhD.Sudhansu K. Dey, PhD, Professor, Director Division of Reproductive Sciences
    Molecular and genetic aspects of embryo implantation in mouse models [Visit the Dey Lab]


    Helen N. Jones, PhD.Helen N. Jones, PhD, Assistant Professor
    My research focuses on placental development and function in pathological pregnancies such as Fetal Growth Restriction and Hypoplastic Left Heart Syndrome. My laboratory is also developing placenta-specific Nanoparticle-mediated gene therapies to improve placental function and pregnancy outcome. [Visit the Jones Lab]

    Louis Muglia, MD, PhD.Louis Muglia, MD, PhD, Professor
    Genetic and developmental mechanisms controlling the timing of birth and risk of preterm birth; molecular genetic analysis of the behavioral and neuroendocrine responses to stress. [Visit the Muglia Lab]

    Satoshi Namekawa, PhD.Satoshi Namekawa, PhD, Assistant Professor
    The long-term goal of my research is to understand the mechanisms and evolution of epigenetic events during mammalian reproduction. We study epigenetic regulation of sex chromosomes during meiosis and the regulatory mechanisms in germline stem cells. [Visit Reproductive Sciences]

    Yuya Ogawa, PhD.Yuya Ogawa, PhD, Assistant Professor
    Molecular mechanisms of long noncoding RNA-mediated epigenetic gene regulation during mammalian development; X-chromosome inactivation using ex vivo differentiation system with mouse ES cells. [Visit Reproductive Sciences]

    Steven Potter, PhD.Steven Potter, PhD, Professor
    Studies of homeobox genes that control mammalian development using gene targeting and transgenic mice [Visit the Potter Lab]

    Michael Williams, PhD.Michael Williams, PhD, Associate Professor
    Interaction of stress-induced hormones and drugs of abuse on adult learning and memory abilities; physiological responses to later stressors; behavioral and physiological consequences of drug reexposure. [Visit the Michael Williams Lab]