ATG (Anti-thymocyte globulin or Atgam) is a medicine used to prevent rejection in different types of transplantation, treatment of graft versus host disease and treatment in certain patients with aplastic anemia. This medication suppresses the body's own immune system. It is available as an injectable medication.

Special Instructions

  • Your child's blood pressure and other vital signs will be checked while this drug is infusing (slowly trickling into the vein). This is because this drug may cause low blood pressure, especially during the infusion.
  • This medication is usually given in the hospital. 
  • Your child will also receive medication to prevent other side effects of ATG during the infusion. These drugs usually consist of acetaminophen, diphenhydramine and / or steroids.
  • This product is made by utilizing horse (equine) immune response cells.
  • This drug must be filtered and given through a central line, and infused in over at least 4 hours. 
  • Keep this medication out of the reach of children.

For any medication information related to your child's dosing schedule and / or missed doses, contact the healthcare provider who prescribed the medication.

Contact your child's doctor if symptoms persist or become bothersome:

  • Back pain
  • Itching, redness or rash
  • Tiredness
  • Sores in the mouth

Call your child's doctor immediately if your child develops:

  • Severe nausea, vomiting, or diarrhea
  • Fever of 101.5 once, or 100.5 twice, in 12 hours
  • Unusual bleeding or bruising
  • Difficulty breathing
  • Chest pain
  • Black or tarry stools

Last Updated 12/2013