Atovaquone (Mepron) is a drug that is used to treat or prevent infections caused by certain protozoa, and other opportunistic infections in immunocompromised patients.

Most commonly, it is used in the treatment of infections caused by Pneumocystis carinii (PCP), Toxoplasma gondii and malaria.

It is available as a suspension that is taken orally.

  • Tell the doctor if your child has a history of kidney, liver, or heart disease.
  • Tell your child's doctor about other medications, including herbal or over-the-counter medicines, that your child is taking.
  • Tell the doctor if your child is also taking rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin). Atovaquone may not work as well if taken with either of these two medicines.
  • Shake bottle before use.
  • Store this medication at room temperature. 
  • Take with a meal, preferably one that is high in fat.
  • Do not use after the expiration date on the bottle/package.
  • Keep using this medicine for full treatment time even if your child feels better after the first few doses. The infection may not clear up if your child stops using the medicine too soon.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC, 513-636-5111 or 1-800-222-1222), or call your child's doctor immediately.

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

  • Headache
  • Difficulty sleeping
  • Nausea
  • Vomiting
  • Upset stomach and abdominal pain
  • Diarrhea
  • Dizziness
  • Cough
  • Severe nausea / vomiting
  • Rash or hives
  • Fever
  • Difficulty breathing
  • Severe stomach pain
  • Allergic reaction: itching / hives, swelling in face or hands

Last Updated 11/2013