Busulfan (Myleran)


Busulfan (Myleran) is a medicine used to treat certain types of cancer and in bone marrow transplantation. It is available as an injectable medication as well as an oral tablet.

  • This medication may affect the color of your child's skin.
  • It is very important to have your child practice good oral hygiene during chemotherapy in order to minimize oral discomfort.
  • If this drug is being used prior to bone marrow transplantation, your child will receive medicine to help prevent a seizure while they are taking this drug. Seizures may occur if your child is taking a high dose of this medication such as what would be used for bone marrow transplantation.
  • Multiple tablets are often given for each dose. Tablets may be placed in clear capsules to help make it easier for your child to take.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC) at 513-636-5111, or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

  • Severe nausea, vomiting, or diarrhea
  • Fever of 101.5 once, or 100.5 twice, within 12 hours
  • Seizures
  • Unusual bleeding or bruising
  • Blood in the urine
  • Yellowing of the skin and/or eyes
  • Blurry vision
  • Difficulty breathing
  • Pain or swelling at the site of the infusion

Last Updated 11/2013