Chlorothiazide (Diuril) belongs to a class of medications known as diuretics.

This medication acts on the kidneys to increase the amount of urine. This helps remove excess water from the body and may help conditions that affect the heart like hypertension.

It may be given as an intravenous (IV) injection, or orally as a tablet or suspension.

  • Chlorothiazide can be given once or twice a day. If it is given once a day, it should be given in the morning at breakfast. If it is given twice a day, give the first dose in the morning and the second dose with the evening meal, but preferably before 6 pm. This will minimize your child's need to go to the bathroom late at night.
  • Take with food.
  • Shake suspension well before giving dose.
  • Avoid excessive exposure to sunlight. Wear sunscreen.
  • Avoid medications like ibuprofen (Advil, Motrin) or naproxen unless advised by your child's doctor, as these agents can decrease the effect of chlorothiazide.
  • Do not use after the expiration date on the bottle / package.
  • If too much medication is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.
  • Dizziness
  • Loss of potassium. (The doctor may want to draw blood periodically to check the potassium level.
  • Increased skin sensitivity to the sun causing the child to burn more easily.
  • Difficulty breathing
  • Heart racing
  • Excessive vomiting and/or diarrhea

Last Updated 11/2013