Cyclophosphamide (Cytoxan)

(sye-klo-FOS-fuh-myde)

Cyclophosphamide is a drug used to treat certain types of cancer. It is also used to treat a variety of other disorders including rheumatoid arthritis, lupus, nephritic syndrome and multiple sclerosis. If you are not sure why your child has been prescribed this medication, please ask your child's doctor to explain the diagnosis and reason for treatment to you. Cyclophosphamide may be given intravenously (IV), or as a tablet that may be taken orally. 

  • Have your child drink large amounts of fluid and urinate often while taking this medication. This will help keep the drug from damaging your child's bladder.
  • This drug is often given in combination with another drug called mesna which can also help to prevent damage to your child's bladder.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC) at 513-636-5111, or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

For any medication information related to your child's dosing schedule and / or missed doses, contact the healthcare provider who prescribed the medication.

  • Hair loss
  • Tiredness
  • Nasal stuffiness and congestion
  • Loss of appetite
  • Swelling of the hands and / or feet
  • Sore throat / mouth or difficulty swallowing
  • Severe nausea, vomiting, or diarrhea
  • Severe throat or mouth pain, or difficulty swallowing
  • Fever
  • Difficulty urinating and / or blood in the urine
  • Changes in the color of urine or stool
  • Bleeding or easy bruising
  • Difficulty breathing
  • Yellowing of skin and / or eyes

Last Updated 12/2013