Busulfan (Myleran)
(byoo-SUL-fan)
What is busulfan (Myleran)?
Busulfan (Myleran) is a medicine used to treat certain types of cancer and in bone marrow transplantation. It is available as an injectable medication as well as an oral tablet.
Special Instructions
- This medication may affect the color of your child's skin.
- It is very important to have your child practice good oral hygiene during chemotherapy in order to minimize oral discomfort.
- If this drug is being used prior to bone marrow transplantation, your child will receive medicine to help prevent a seizure while they are taking this drug. Seizures may occur if you child is taking a high dose like those used for bone marrow transplantation.
- Multiple tablets are often given for each dose. Tablets may be placed in clear capsules to help your child take dose.
- If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately.
- Keep this medication out of the reach of children.
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If a dose is missed
For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.
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Side effects
Contact your child's doctor if symptoms persist or become bothersome:
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Warning signs
Call your child's doctor immediately if your child develops:
- Severe nausea, vomiting, or diarrhea
- Fever 101.5 once or 100.5 twice in 12 hours
- Seizures
- Unusual bleeding or bruising
- Blood in the urine
- Yellowing of the skin and/or eyes
- Blurry vision
- Difficulty breathing
- Pain or swelling at the site of the infusion
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Contact us
For additional information on this or any Health Topic, please call the Family Resource Center, 513-636-7606, or your pediatrician.
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PEP 5022 V Rev. 9/05, 8/07
