Isotretinoin (13-cis-retinoic acid)
Definition | Special instructions | Missed dose | Side effects | Warning signs | Contact us
(eye-soe-TRET-i-noyn)
What is isotretinoin (13-cis-retinoic acid, or AccutaneÒ)?
Isotretinoin (13-cis- retinoic acid, Accutane) is thought to help with regulating cell growth and is used in the treatment of certain types of cancer in addition to chemotherapy. Also, it is used to treat severe acne. It is available as capsule.
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Special Instructions
- Take by mouth with a full glass of water. Take with food.
- Do not crush capsules.
- If your child wears contact lenses, this drug may cause them not to be able to wear them because it causes dry eyes.
- Females of child bearing age should have a pregnancy test prior to starting this medication.
- Females of child bearing age should use two forms of birth control while taking this medication. Taking this medication while pregnant can cause very serious birth defects. If you become pregnant while using this medication, tell your doctor immediately.
- This drug my cause dry mouth. Sugarless gum, hard candy, water, or ice chips may help with this side effect.
- Before starting any new medications, including vitamins, talk to your child's doctor.
- This drug may increase your child's sensitivity to the sun. Be careful to limit your child's sun exposure and to have them use sunscreen (SPF 15) and wear protective clothing (long sleeves and hats) when going outside.
- Store medication at room temperature away from moisture and sunlight. Do not refrigerate. Do not store in the bathroom.
- Do not use after the expiration date on the bottle/package.
- If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately.
- Keep this medication out of the reach of children.
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If a dose is missed
For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.
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Side effects
Contact your child's doctor if symptoms persist or become bothersome:
- Loss of appetite
- Stomach ache
- Thirst or dry mouth
- Dry peeling lips
- Redness of the lips and eyes
- Changes in eyesight or eye sensitivity to the sun
- Joint pains and/or muscle aches
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Warning signs
Call your child's doctor immediately if you child develops:
- Severe nausea, vomiting, or diarrhea
- Rash
- Fever
- Bleeding or easy bruising
- Blood in the urine
- Numbness or tingling
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Contact us
For additional information on this or any Health Topic, please call the Family Resource Center, 513-636-7606, or your pediatrician.
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PEP 5082 V 6/04
Rev. 9/05, 10/07