Cancer Medications

Leucovorin

(loo-koe-VOR-in)

Definition | Special instructions | Missed dose | Side effects | Warning signs | Contact us

What is leucovorin (folinic acid)?

Leucovorin or folinic acid is a drug used to help normal cells recover after treatment with the chemotherapy drug Methotrexate. It is available as an injectable medication as well as a tablet for oral use.

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Special Instructions

  • It is very important that this drug be given exactly as scheduled
  • Leucovorin is usually given in the hospital
  • Your child's doctor may want to draw blood to help determine exactly how long to continue with leucovorin therapy
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately
  • Keep this medication out of the reach of children

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If a dose is missed

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

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Side effects

Side effects of leucovorin alone are rare. Allergic reactions have been reported.

Warning signs

Call your child's doctor immediately if you child develops:

  • If your child misses a dose or is unable to keep down an oral dose
  • Severe nausea, vomiting, or diarrhea
  • Sever throat or mouth pain, or difficulty swallowing
  • Rash
  • Fever
  • Blood in urine or stools
  • Black tarry stools
  • Bleeding or easy bruising

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Contact us

For additional information on this or any Health Topic, please call the Family Resource Center, 513-636-7606, or your pediatrician.

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PEP 5020 V 4/04
Rev. 9/05, 8/07