Mitoxantrone
(my-toe-ZAN-trone)
Definition | Special instructions | Side effects | Warning signs | Contact us
What is mitoxantrone?
Mitoxantrone (Novantrone") is a chemotherapy medicine used to treat cancer. It is given through an injection into a vein.
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Special instructions
- If this medication leaks out of the vein, it may cause a blue streak along the vein. Urine and the whites of the eyes may be blue-green for up to 48 hours after infusion. This is only a temporary change and it is not harmful to your child.
- Frequent, small meals may help if your child experiences severe nausea.
- Use precaution when changing your child's diapers or soiled linens for 48 hours after a dose – use gloves during this time to avoid contact with the medication.
- This medicine is only given in the hospital or clinic.
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Side effects
- Hair loss
- Low blood counts (decreased white blood cells needed to fight infection and decreased platelets that are necessary for proper blood clotting)
- Liver problems
- Lung problems (rare)
- Heart problems
- Headaches
- Seizures
- Upset stomach
Report to your child's doctor if the following side effects continue longer than 24 hours: nausea, vomiting, diarrhea, mouth sores.
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Warning signs
Call your child's doctor if your child experiences:
- Fever
- Bruising or bleeding
- Sore throat
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Contact us
For additional information on this or any Health Topic, please call the Family Resource Center, 513-636-7606, or your pediatrician.
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Patient Education Program V 5068 5/01
Rev. 9/05, 8/07
