Cancer Medications

Prednisone, Prednisolone, Methylprednisolone

(PRED-ni-sone, pred-NIS-oh-lone, meth-il-pred-NIS-oh-lone)

Definition | Special instructions | Missed dose | Side effects | Warning signs | Contact us

What are prednisone, prednisolone and methylprednisolone?

Prednisone, prednisolone and methylprednisolone (Prelone", Pediapred", Deltasone", Orapred", Medrol") are oral steroids used to reduce swelling and inflammation of the bronchi, which are the airways of the lungs. This medication is also used to treat skin disorders, arthritis, allergic reactions, and to prevent transplant rejection. Prednisone and prednisolone may be taken in a tablet or liquid form. Methylprednisolone is available as a tablet.

Special instructions

  • Dosage varies with each child and can only be prescribed by your child's doctor
  • It is very important that your child takes this medication exactly as prescribed by the doctor and that doses are not missed
  • Talk with your child's doctor about side effects and proper dosing schedule if your child will be taking steroids for more than 1-2 weeks
  • Never give your child steroids without first talking to your child's doctor
  • Never stop giving your child steroids without asking your child's doctor
  • Take this medication with food to decrease stomach upset
  • If your child is going to have surgery or other stressful situations while on steroids, talk to your child's doctor
  • Do not use after the expiration date on the bottle/package
  • Keep this medication out of the reach of children
  • If too much medication is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately

If a dose is missed

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

Side effects

Contact your child's doctor if symptoms persist or become bothersome:
  • Increased hunger
  • Moodiness/mood swings
  • Increased blood sugar
  • Infection: sore throat, fever, nausea, vomiting, diarrhea
  • Decreased bone growth
  • Increased weight gain
  • Stomach ulcers

Warning signs

Call your child's doctor immediately if your child has any of the following:
  • Wheezing
  • Difficulty breathing
  • Swelling of face, lips, tongue or throat
  • Vomiting of blood
  • Dizziness
Call your child's doctor if any of the following are severe or continue: sore throat, fever, stomach pain, skin rash, muscle cramps, nausea, vomiting, or diarrhea. Other signs to watch for are swelling of feet, tiredness, appetite changes, weight gain, puffy face, mood changes, increased thirst, blurred vision, menstrual problems, or slow healing of sores.

Contact us

For additional information on this or any Health Topic, please call the Family Resource Center, 513-636-7606, or your pediatrician.

Patient Education Program V 5123 12/98
Rev. 10/05, 8/07