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Cancer Medications

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Sargramostim

Definition | Special instructions | Missed dose | Side effects | Warning signs | Contact us

(sar-GRAM-oh-stim)

What is sargramostim or GM-CSF (Leukine")?

Sargramostim or GM-CSF is used to help your child make more white blood cells so that they can more effectively fight infection. It is most often used after chemotherapy or bone marrow transplantation to help your child recover from the effects of the chemotherapy faster. It is available as an injectable medication that is either given subcutaneous (under the skin) or through an intravenous (IV) line.

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Special Instructions

  • Do not shake the vial. This may cause the drug to be less effective.
  • Store this medication in the refrigerator.
  • The dose should be given at approximately the same time each day.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

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If a dose is missed

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

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Side effects

Contact your child's doctor if symptoms persist or become bothersome:

  • Bone pain especially in the lower back, hip and breast bone
  • Fluid retention
  • Headache
  • Persistent cough
  • Increased thirst
  • Pain at the injection site

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Warning signs

Call your child's doctor immediately if your child develops:

  • Severe nausea, vomiting, or diarrhea
  • Dizziness, flushing, or fast heart rate
  • Chest pain
  • Unusual or easy bruising or bleeding
  • Wheezing or difficulty breathing
  • Rash
  • Fever

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Contact us

For additional information on this or any Health Topic, please call the Family Resource Center, 513-636-7606, or your pediatrician.

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PEP 5071 V 6/04
Rev. 10/05, 9/07