Leucovorin, or folinic acid, is a drug used to help normal cells recover after treatment with methotrexate, a chemotherapy drug.

It is available as an injectable medication as well as a tablet for oral use.

  • It is very important that this drug be given exactly as scheduled.
  • Leucovorin is usually given in the hospital.
  • Your child's doctor may want to draw blood to help decide exactly how long to continue with leucovorin therapy.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

For questions about your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

Side effects of leucovorin alone are rare. Allergic reactions have been reported.

  • Your child misses a dose or is unable to keep down an oral dose
  • Severe nausea, vomiting, or diarrhea
  • Sever throat or mouth pain, or difficulty swallowing
  • Rash
  • Fever
  • Blood in urine or stools
  • Black tarry stools
  • Bleeding or easy bruising

Last Updated 11/2013