L.M.X.4 (Lidocaine 4%)

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L.M.X.4 (Lidocaine 4%)

L.M.X.4 is a topical anesthetic cream that is similar to EMLA.

At the nerve endings, L.M.X.4 causes numbing of the skin and surrounding tissue.

	L.M.X.4	EMLA
Prescription Status	Over-the-Counter	Prescription Only
Active Ingredients	Lidocaine 4%	Lidocaine 2.5% / Prilocaine 2.5%
Recommended Application Time	30 min – Venipuncture/LP	60 min – Venipuncture/LP 120 Min – Skin graft harvesting 5-15 min – genital mucosa
Maximum Application Time	60 min (no added benefit with longer application) May be left on up to 120 min	60 min (<3mo or <5kg) 240 min (4 hrs) for all others
Duration of Effect	60 min after removal	60-120 min after removal
ADR's	Redness, irritation, itching, rash	Local blanching, redness, erythema, Methemoglobinemia
FDA Approved Ages	>2 years old	>37 weeks EGA
FDA Approved Uses	Minor cuts, minor burns, minor scrapes, minor skin irritations, sunburn, and insect bites	IV catheter placement, Venipuncture, split skin graft harvesting, genital mucosa (adjunct to local infiltration)
Non-FDA Approved uses studied in children	IV catheter placement, Venipuncture, circumcision, LP	Circumcision, anal fissures, IM Immunizations, LP, cryotherapy for warts
Warnings/Precautions	Do no use on raw areas or blisters	Use with caution in patients at risk for developing Methemoglobinemia or with severe hepatic disease
Size	5, 15, 30gm tubes. 5gm tube has 3 Tegaderm patches.	30gm tube

Last Updated: 08/2010