6-Mercaptopurine

(mer-kap-to-PYOOR-een)

6-Mercaptopurine (Purinethol) is a medicine used to treat certain types of cancer and in the treatment of Crohn's disease. It is administered by mouth as a tablet, or suspension.

It is best to take this medication on an empty stomach one hour before a meal or two hours after a meal.

This medication can be given at bedtime to decrease nausea.

It is best to take this medication at the same time each day.

Your child's doctor may want to have your child's blood drawn while taking this medication in order to monitor for side effects of the drug.

This is a hazardous medication and should be used with caution. Parents should wear gloves when handling this medication.

Store medication at room temperature away and from moisture and sunlight. Do not refrigerate. Do not store in the bathroom.

Do not use after the expiration date on the bottle / package.

If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately. Keep this medication out of the reach of children.

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

  • Soreness in the mouth or throat
  • Loss of appetite
  • Nausea
  • Severe nausea, vomiting, or diarrhea
  • Signs of jaundice including yellowing of the skin and eyes
  • Loss of balance, lack of coordination, or sleepiness
  • Fever of 101.5 once or 100.5 twice in 12 hours
  • Unusual bleeding or bruising
  • Severe sore throat or difficulty swallowing

Last Updated 10/2013