Mesna (Mesnex)


Mesna is a medicine used to prevent bladder-related side effects of some chemotherapy drugs like cyclophosphamide (Cytoxan) and ifosfamide.

This medication comes as an injectable drug, and as a tablet that is taken by mouth.

  • This drug is usually given by injection, rather than taken by mouth. If this medication is given by mouth, it should be taken on an empty stomach. (Take with water, milk, juice, or carbonated beverages to help mask the bitter taste.)
  • It is very important that your child take all of the prescribed doses and that no doses are missed or delayed. Call your child's hematologist, the clinic, or the hematologist on call if your child vomits after a dose taken by mouth.
  • Store medication at room temperature away from moisture and sunlight. Do not refrigerate or store in the bathroom.
  • Do not use after the expiration date on the bottle / package.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC), 513-636-5111 or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

For any questions about your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

  • Severe nausea, vomiting, or diarrhea
  • Rash
  • Painful or difficulty urinating
  • Bloody urine
  • Abnormal bruising or bleeding

Last Updated 11/2013