Omeprazole (Prilosec) is a medicine that is used to decrease the amount of acid that is made by the stomach. It may be used to treat ulcers, gastroesophageal reflux (GER or GERD), and heartburn. It is available as tablet, capsule, and powder for oral suspension. Your pharmacy may also be able to make a liquid for you.

  • Do not crush or chew the capsules or tablets. The drug may not work if the tablet or capsule is chewed or crushed.
  • Mix the powder for oral suspension with 2 tablespoons of water immediately before taking. Do not use any other liquid. Do not put the suspension through a G-tube, NG-tube, or J-tube.
  • Some patients who cannot swallow capsules or tablets may be able to take a liquid form of omeprazole prepared by the pharmacy. This form may be given through a G-tube, NG-tube or J-tube. Be sure to flush the tube well.
  • If your child has a NG-tube or G-tube you may also be able to mix the beads from the inside of the capsule in acidic juice such as apple, cranberry, grape, orange, grapefruit, pineapple, prune, tomato, or V-8 before giving through the tube. Do not crush the beads. Be sure to flush the tube well.
  • This medicine works best if taken before eating. Antacids may be taken with omeprazole if your child's doctor instructs you to give them.
  • Store at room temperature away from moisture and sunlight. Do not store in the bathroom.
  • Do not use after expiration on bottle/package.
  • Keep this medication out of the reach of children.
  • Make sure your doctor knows about other medications your child is taking.
  • If too much medication is taken by accident, call the Drug and Poison Information Center (DPIC) at 513-636-5111, or 1-800-222-1222 or call your child's doctor right away.
  • Stomach pain
  • Diarrhea
  • Constipation
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Dry mouth
  • Back or joint pain
  • Cough or chest pain
  • Sore throat or fever
  • Possible bone fractures if this medication is used for long periods of time (more than 1-2 years)
  • Skin rash
  • Bloody or cloudy urine
  • Unusual bleeding or bruising
  • Pain or problem urinating
  • Ringing in the ears
  • Coughing up blood
  • Dark or black colored stools
  • Trouble breathing or chest tightness

Last Updated 12/2013