(peg a-SPIR-a-ji-nase) 

PEG-asparaginase is a medicine used to treat certain types of cancer. It is available as an injectable medication that can be given intramuscularly (into the muscle).

  • Allergic reactions are common with this medication. Your child's doctor may want to observe your child in the hospital after giving this medication to make sure that he / she is not having a reaction to the drug.
  • If your child experiences an allergic reaction to PEG-asparaginase the doctor may want to change your child to a different, but similar, medication to complete the course of chemotherapy.
  • Have your child drink plenty of fluids while taking this medication to ensure adequate hydration.
  • Do not use after the expiration date on the bottle / package.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC) at 513-636-5111, or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

For any medication information related to your child's dosing schedule and / or missed doses, contact the healthcare provider who prescribed the medication.

  • Nausea, vomiting
  • Loss of appetite
  • Drowsiness
  • Soreness, redness, or swelling at the injection site
  • Increased thirst, appetite, or urination
  • Severe nausea, vomiting, or diarrhea
  • Severe abdominal or back pain
  • Rash, Lip Swelling
  • Confusion
  • Fever, chills, headache, cough
  • Easy bruising
  • Trouble breathing or chest pain
  • Seizures (or convulsions)

Signs of an allergic reaction may include fever, chills, rash, itching, hives, puffy face and difficulty breathing. Call your child's doctor immediately if you see signs of an allergic reaction.

Last Updated 12/2013