Procarbazine

(proe-KAR-ba-zeen)

Procarbazine (Matulane®) is a medicine used to treat certain types of cancer. It is available as a capsule.

  • Take this medication with food.
  • Have your child drink plenty of fluids while taking this mediation to ensure adequate hydration.
  • Avoid drinking alcohol while taking this medication. Alcohol in combination with procarbazine may result in vomiting and / or facial flushing.
  • Avoid foods that contain high amounts of tyramine including wine, cola drinks, tea, aged cheeses and aged meats, such as sausage. Ask your child's doctor or dietician for more information regarding which food contain high amounts of tyramine.
  • This drug may increase your child's sensitivity to the sun. Be careful to limit your child's sun exposure. If going outside, have them use sunscreen (SPF 15) and wear protective clothing (long sleeves and hats).
  • Store medication at room temperature away from moisture and sunlight. Do not refrigerate. Do not store in the bathroom.
  • Do not use after the expiration date on the bottle / package.
  • If too much medicine is taken by accident, call the Drug and Poison Information Center (DPIC) at 513-636-5111, or 1-800-222-1222, or call your child's doctor immediately.
  • Keep this medication out of the reach of children.

For any medication information related to your child's dosing schedule and/or missed doses, contact the healthcare provider who prescribed the medication.

  • Hair loss
  • Soreness in the mouth or throat
  • Skin changes including dry skin, rash and sunburning
  • Loss of appetite
  • Persistent cough
  • Severe nausea, vomiting, or diarrhea
  • Loss of balance, lack of coordination, or sleepiness
  • Fever of 101.5 once, or 100.5 twice, in 12 hours, chills, headache
  • Unusual bleeding or bruising
  • Severs sore throat
  • Seizure
  • Chest pain or difficulty breathing

Last Updated 12/2013