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Summer 2005

Welcome to Research Horizons

Explore highlights of the exciting research happening at Cincinnati Children's Research Foundation with Research Horizons. Each issue features recent studies published by Cincinnati Children's investigators. By combining cutting-edge research and education with the best in pediatric care, we are striving to improve the lives of children and families everywhere.

This issue features the following news briefs:

In addition, you will find the following feature stories that highlight some of our many world-class researchers:

International Activities Abound at Cincinnati Children's

The Cincinnati Children's community is a global one, and this is seen in our research as well as our patient care. In this issue of Research Horizons we examine some of our internationally focused programs and our researchers from outside the United States. [more]

Developing Computer Models for Personalized Drug Dosing

Sander Vinks works in his lab."Developing better methods for individual drug dosing" is how Alexander (Sander) Vinks, PharmD, PhD, describes the motivating force behind his current clinical pharmacology research projects. [more]

Mary Staat Finds Inspiration in International Health

Mary Staat has a follow-up visit with Lana Moore, adopted from RussiaMary Staat, MD, MPH, is a clinician and researcher in the Division of Infectious Diseases. She is also founder and director of the International Adoption Center (IAC) at Cincinnati Children's, as well as the mother of three internationally adopted children. A long-time interest in international health has led these paths to cross. [more]

Understanding Mechanisms of Systemic-Onset Juvenile Idiopathic Arthritis

Systemic-onset juvenile idiopathic arthritis is one of the most devastating rheumatic diseases in childhood. Spiking fevers, rash, and enlarged lymph nodes, spleen and liver are characteristic manifestations of systemic inflammation that can also involve the heart, lungs and blood vessels. Alexei Grom, MD, of the Division of Rheumatology at Cincinnati Children's is working to to identify an "early diagnostic signature" that would identify patients bound to develop severe joint damage. [more]

Profile: Ardythe Morrow Takes a Worldwide View of Child Health

Ardythe Morrow combines a passion for improving child health with international interests.Ardythe Morrow, PhD, is an academic entrepreneur with an intense commitment to improving child health. Recruited to direct and develop the Center for Epidemiology and Biostatistics and recognized for her research on human breast milk, Dr. Morrow also is working to create a cohesive international presence for Cincinnati Children's. [more]

Tackling the Challenges of Food Allergies

Amal Assa'ad visits with a patient during a clinic visit.As a researcher and clinician, Amal Assa'ad, MD, willingly takes on challenges so that patients with food allergies may be able to avoid food challenges -- a distasteful way of identifying food allergens -- as well as challenges of living with food allergies. [more]