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Summer 2006

Research Horizons at Cincinnati Children's Research Foundation

Explore highlights of the exciting research happening at Cincinnati Children's Research Foundation with Research Horizons. Each issue features recent studies published by Cincinnati Children's investigators. By combining cutting-edge research and education with the best in pediatric care, we are striving to improve the lives of children and families everywhere.

This issue features the following news briefs:

In addition, you will find the following feature stories that highlight some of our many world-class researchers:

Infatuated With Vaccine Research

infatuated with vaccine researchCincinnati Children's has had a long-standing relationship with vaccine research. You might even call it an infatuation. Our commitment to vaccine research dates back to the 1950s when Albert Sabin, MD, first began his work on developing the live oral polio vaccine. [more]

Generations Benefit From the Work of Vaccine Researcher Gilbert Schiff

Gilbert SchiffResearcher, physician, president, professor. Infectious disease specialist Gilbert Schiff, MD, has worn many hats in his long and distinguished career at the Centers for Disease Control, National Institutes of Health (NIH), University of Cincinnati, James N. Gamble Institute of Medical Research and Cincinnati Children's. [more]

Pediatricians Likely to Recommend New HPV Vaccine

Jessica KahnWhen a human papillomavirus vaccine becomes available in the very near future, will pediatricians recommend it to patients and their parents? The answer is yes, according to recent research by Jessica Kahn, MD, MPH, of the Cincinnati Children's Division of Adolescent Medicine. [more]

Stopping the Avian Flu Before it Takes Off

researchersAs a Vaccine and Treatment Evaluation Unit (VTEU), Cincinnati Children's is one of seven sites testing vaccines that may one day attack the avian flu mid-flight. Researchers in the Division of Infectious Diseases are conducting clinical trials in adults and the elderly on a vaccine that could combat H5N1, the strain of avian influenza that has shown up in more than 200 humans since 1997. [more]

Tackling Noroviruses to Aid Public Health and National Defense

Xi Jiang and AssociateIn 18 years of working with noroviruses, Xi Jiang, PhD, has been instrumental in reaching major milestones on the way to controlling and preventing the most common cause of viral gastroenteritis. While still a postdoctoral student at Baylor College of Medicine in Houston, Texas, Dr. Jiang cloned the first norovirus. Now, as director of the norovirus program and professor in the Division of Infectious Diseases at Cincinnati Children's, he is working to develop vaccines or antivirals to stop noroviruses before they can inflict sickness. [more]

Taking Rotavirus Vaccine From the Lab to the World

Dick WardIn February 2006, the European Union (EU) announced that the rotavirus vaccine Rotarix™, developed and first tested by Cincinnati Children's researchers Richard Ward, PhD, and David Bernstein, MD, was approved for commercial use in its member countries. The addition of the EU countries brings the total to more than 60 countries now providing this vaccine to their children. [more]