News in Brief
Cincinnati Children's Ranks Second in NIH Grants
Cincinnati Children's now ranks second in the nation among all pediatric medical centers in research funding from the National Institutes of Health (NIH). "Our leadership position in pediatric research means that we also will be leaders in clinical innovation," says Thomas Boat, MD, director of the Cincinnati Children's Research Foundation. Among the reasons he cites for the lofty research rank are strong research leadership at the institutional and divisional levels, resources that enhance access to technology and data analysis, unwavering institutional support and internal start-up grants.
Radiology Department Among Most Influential
RT Image magazine recently ranked the Department of Radiology and Medical Imaging at Cincinnati Children's among the top 25 Most Influential in Radiology. The issue was a compilation of the best people, organizations and institutions impacting the radiology industry. They were rated by performance in the past year as well as possible impact for the coming year. "It is a great honor to be in a group that includes giants in the field such as the American College of Radiology and the Radiological Society of North America," says Lane Donnelly, MD, radiologist-in-chief at Cincinnati Children's.
Findings Uncover Potential Target for Leukemia Treatment
Cincinnati Children's announced the publication of pioneering research identifying the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. The findings, along with other studies, suggest that RhoH GTPase may provide a target for therapeutic intervention in some types of leukemia. The paper describes detailed genetic and biochemical studies undertaken by researchers in the Divisions of Experimental Hematology and Immunobiology. It is due to appear in an upcoming edition of Nature Immunology and was posted in the advance online publication section of the journal's web site.
Tobacco Smoke, Lead Exposure Linked to ADHD
A new study finds that prenatal exposure to tobacco smoke and childhood exposure to lead account for about one-third of Attention Deficit Hyperactivity Disorder (ADHD) cases among children in the United States. "Our analysis confirms a suspected link between prenatal tobacco exposure and ADHD, and it demonstrates that the greater the level of blood lead, the greater the risk of ADHD," says Bruce Lanphear, MD, director of the Children's Environmental Health Center at Cincinnati Children's and corresponding author of the study. Cincinnati Children's is addressing the importance of modeling healthy behaviors by going tobacco free with 20 area hospitals on January 1, 2007.
Grant Funding an Integral Component of Research Foundation
Cincinnati Children's has a renowned research staff that attracts millions of dollars in research funding and private and corporate donations annually. These funds are reinvested into research supplies, equipment and salaries so our researchers have the resources to continually "raise the bar" in the pediatric health care field. We are ranked second in funding among comprehensive pediatric centers receiving National Institutes of Health (NIH) research grants. Recent grants obtained include the following:
| Cripe, T. | Oncolytic HSV Cancer Therapy in Immunocompetent Models National Institutes of Health; 7/1/06 - 5/31/11; $887,500 |
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| Gittelman, M. | Community Based Obesity Prevention; Robert Wood Johnson Foundation 12/1/05 - 5/31/07; $54,069 |
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| Kowatch, R. | Family-Focused Treatment for Bipolar Adolescents National Institutes of Health; 7/1/06 - 4/30/11; $971,184 |
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| Lannon, C. | Partnership to Improve Children's Healthcare Quality Agency for Healthcare Research and Quality; 1/30/06 - 9/29/06; $153,666 |
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| Palumbo, J. | Mechanisms Linking Metastasis to Tumor Procoagulant and Innate Immunity National Institutes of Health; 7/20/06 - 6/30/11; $1,250,000 |
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| Powers, S. | Drug and Non-Drug Treatment of Pediatric Chronic Headache National Institutes of Health; 7/1/06 - 6/30/10; $1,277,481 |
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| Spanier, A. | Environmental Exposures, NOS Genes, and Exhaled Nitric Oxide in Pediatric Asthma National Institutes of Health; 7/1/06 - 6/30/08; $200,000 |
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| Yutzey, K. | TBX20 Regulation of Heart Valve Development National Institutes of Health; 7/1/06 - 6/30/10; $1,000,000 |
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