Cincinnati Children's Hospital Medical Center
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Researchers have successfully targeted an important molecular pathway that fuels a variety of cancers and related developmental syndromes called “Rasopathies.” Reporting their results Nov. 20 in Chemistry & Biology, scientists at Cincinnati Children’s Hospital Medical Center say they identified a class of lead compounds that successfully recognize a key target in the Ras signaling pathway – opening the door to future development of therapies that could make treatments more effective with fewer side effects.
Conclusive data show that hydroxyurea therapy offers safe and effective disease management of sickle cell anemia (SCA) and reduces the risk of stroke, prompting early termination by the National Heart Lung and Blood Institute (NHLBI) of a key clinical trial studying the drug’s efficacy. NHLBI officials issued the announcement today, about one year before the study was originally scheduled to end. The study was led by Cincinnati Children's and Principal Investigator Russell Ware, MD, director of Hematology at the medical center.
The sound of monitor alarms in hospitals can save patients’ lives, but the frequency with which the monitors go off can also lead to “alarm fatigue,” in which caregivers become densensitized to the ubiquitous beeping.
Cincinnati Children’s Hospital Medical Center has opened its newest urgent care center at the hospital’s Liberty Campus, located on Yankee Road. This represents a continued commitment from the medical center to provide care to Greater Cincinnati’s pediatric population.
A study to be released in the November issue of Health Affairs shows that integrating community housing data on such code violations as mold and cockroaches with health data can identify at-risk geographical areas of medical concern and help target patients for medical interventions.