Cincinnati Children's Hospital Medical Center

Press Release Form

Release Details
Title   Infant Pertussis Hospitalizations Lower Than Expected After Teen Vaccinations 
SubTitle  
Contact Information  
Nick Miller, 513-803-6035, nicholas.miller@cchmc.org
Release Body  

Widespread vaccination of adolescents for pertussis was associated with lower rates of infant hospitalizations for the respiratory infection than would have been expected had teens not been inoculated according to new research in Pediatrics.

Reporting their results online Oct. 21, researchers said the study underscores the importance of increasing vaccination rates among teens and adults to stem an ongoing pertussis epidemic among infants. The research was conducted by physicians at Cincinnati Children’s Hospital Medical Center and the University of Michigan.

The ongoing epidemic has been linked to waning immunity and the failure to vaccinate, according to Katherine A. Auger, MD, MSc, the study’s lead author and a pediatrician in Division of Hospital Medicine at Cincinnati Children’s.

“We know infants get pertussis from family members, including older siblings,” Auger said. “While it is encouraging to find a modest reduction in infant hospitalizations after the vaccination of adolescents began, there were still more than 1,000 infants hospitalized for pertussis in 2011. Expecting parents should discuss with their doctors the need for vaccination of all caregivers before the birth of a baby.”

The current study was initiated following recommendations by the Centers for Disease Control in 2006 to vaccinate all adolescents against pertussis. Researchers used data from the Nationwide Inpatient Sample, a database maintained by the U.S. Agency for Healthcare Research and Quality.

Investigators examined pertussis hospitalization rates for infants after the new adolescent vaccine recommendations were made and compared them to predicted hospitalization rates had adolescent vaccinations not been implemented. Hospitalization data from 2000 to 2005 – prior to the teen vaccination recommendations – were used to predict hospitalization rates had adolescent vaccinations not been implemented.

In three of the four years examined after the teen vaccination recommendations (2008-2011), investigators found lower hospitalization rates for infants than would have been expected with no adolescent vaccinations.

In 2011 for example, the expected hospitalization rate for pertussis if adolescent vaccinations had not been implemented was 12 hospitalizations per 10,000 infants. The observed rate following the teen vaccinations was significantly lower at 3.27 hospitalizations per 10,000 infants.

Pregnant women should receive pertussis vaccination during pregnancy, according to a recommendation made by the Centers for Disease Control in 2012. Auger said future research will be needed to assess how and if this policy change further affects pertussis hospitalization rates in infants.

Study authors received funding from the Robert Wood Johnson Foundation through the Clinical Scholars program.

About Cincinnati Children’s

Cincinnati Children’s Hospital Medical Center ranks third in the nation among all Honor Roll hospitals in U.S.News and World Report’s 2013 Best Children’s Hospitals ranking. It is ranked #1 for cancer and in the top 10 for nine of 10 pediatric specialties. Cincinnati Children’s is one of the top three recipients of pediatric research grants from the National Institutes of Health, and a research and teaching affiliate of the University of Cincinnati College of Medicine. The medical center is internationally recognized for improving child health and transforming delivery of care through fully integrated, globally recognized research, education and innovation. Additional information can be found at www.cincinnatichildrens.org. Connect on the Cincinnati Children’s blog, via Facebook and on Twitter.

Publish Date   2013-10-21  
Publish Time   00:01 24 hour (HH:MM) time only. AM / PM declarations will invalidate the value.
Cancer Center News

Sidebar

*Sidebar Title is required if you add any media to the page (Windows Media Video, Quick Time, Flash, Image, PDF, Audio, etc)

Sidebar Title  

Sidebar Description

Subhead

Subhead Title 

Subhead Description

YouTube

 

Media File  

Media Type

None

Screen Shot Default Screen Shot (Blue)  

Flash Aspect Ratio: 16:9  

Recent News Releases

Tuesday, December 16, 2014 - Cincinnati Children’s Hospital Medical Center Employee Receives National Recognition

Dawne Gardner, MBA, of Cincinnati Children’s Hospital Medical Center and the Comprehensive Children’s Injury Center (CCIC) was named as the Injury Free Coalition for Kids Program Coordinator of the Year.

Wednesday, December 10, 2014 - Study Links ADHD and Conduct Disorder With Increased Alcohol and Tobacco Use in Young Teens

A new study links ADHD and conduct disorder in young adolescents with increased alcohol and tobacco use. The Cincinnati Children’s Hospital Medical Center study is among the first to assess such an association in this age group.

Monday, December 01, 2014 - Cincinnati Children’s Studying Impact of Concussions on Teen Drivers

Researchers at Cincinnati Children’s Hospital Medical Center are currently studying teenagers who have suffered concussions in order to help doctors determine when teen drivers are ready to get back behind the wheel of a vehicle.

Wednesday, November 26, 2014 - Cincinnati Children’s Expert Gives Tips on How to Eat Healthy During the Holidays

Allison Bourgraf, RD, LD, a clinical dietitian in the Division of Nutrition Therapy at Cincinnati Children’s Hospital Medical Center, shares the following tips on how parents and children can enjoy tasty foods during the holiday season and still stay healthy.

Thursday, November 20, 2014 - Researchers Report Way to Target Hard-to-Hit Site in Disease Pathway

Researchers have successfully targeted an important molecular pathway that fuels a variety of cancers and related developmental syndromes called “Rasopathies.” Reporting their results Nov. 20 in Chemistry & Biology, scientists at Cincinnati Children’s Hospital Medical Center say they identified a class of lead compounds that successfully recognize a key target in the Ras signaling pathway – opening the door to future development of therapies that could make treatments more effective with fewer side effects.