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A researcher at Cincinnati Children’s is evaluating a rapid gene test that could identify dangerous infections among hospitalized children before they suffer potentially deadly harm.
Hector Wong, MD, director, Division of Critical Care Medicine, has been awarded a three-year, $1.5 million grant from the National Institute of General Medical Sciences to pursue new ways to battle septic shock, one of the leading causes of death among hospitalized children.
An estimated 20,000 to 42,000 children a year suffer severe sepsis in the United States and about 4,500 children a year die, according to a study recently published in Critical Care Research and Practice by Cincinnati Children’s researchers Carley Riley, MD, and Derek Wheeler, MD.
Although survival rates have improved dramatically since the 1960s, better ways to detect the early signs of sepsis are needed to further reduce deaths.
“Through this new grant, our research program has evolved to a new phase,” Wong says. “By leveraging genomic data, we can develop new diagnostic tools for septic shock that can enhance decision making in the ICU, support quality improvement work and help identify candidates for clinical trials.”
The study has three key parts:
Hector Wong, MD.
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