General and Thoracic Surgery

Faculty Members

Richard G. Azizkhan, MD,  Professor ; Surgeon-in-Chief, Division Director

Maria H. Alonso, MD,  Associate Professor ; Surgical Associate Director, Liver Transplant; Surgical Director, Kidney Transplant

Denis D. Bensard, MD,  Professor ; Director, Pediatric Surgery, St. Vincent Children's Hospital

Rebeccah L. Brown, MD,  Associate Professor ; Associate Director, Trauma Services

Timothy M. Crombleholme, MD,  Professor ; Obstetrics/Gynecology, and Pediatrics, Director, Fetal Care Center of Cincinnati

A. Roshni Dasgupta, MD,  Assistant Professor

Richard A. Falcone, MD, MPh,  Assistant Professor ; ECMO Director, Associate Director, Trauma Services

Victor F. Garcia, MD,  Professor ; Director, Trauma Services; Associate Surgical Director, Comprehensive Weight Management Center

Richard J. Hendrickson, MD,  Assistant Professor ; Associate Director, Pediatric Surgery, St. Vincent Children's Hospital

Thomas H. Inge, MD, PhD,  Associate Professor ; Surgical Director, Comprehensive Weight Management Center

Marc A. Levitt, MD,  Associate Professor ; Associate Director, Colorectal Center for Children

Foong-Yen Lim, MD,  Assistant Professor

Alberto Peña, MD,  Professor ; Director, Colorectal Center for Children

Frederick C. Ryckman, MD,  Professor ; Surgical Director, Liver Transplant; Clinical Director

Gregory M. Tiao, MD,  Assistant Professor ; Associate Program Director, Fellowship

Joint Appointment Faculty Members

Jeffrey Livingston, MD,  Associate Professor

Maternal Fetal Medicine

Trainees

• Shawn Rangel, MD,  PL-10,  Stanford University
• Sean Barnett, MD,  PL-8,  University of Minnesota

Significant Accomplishments in FY08

 Molecular Fetal Lab

 Bariatric Surgery

 Biliary Atresia

Significant Publications in FY08

Crombleholme TM, Shera D, Lee H, Johnson M, D'Alton M, Porter F, Chyu J, Silver R, Abuhamad A, Saade G, Shields L, Kauffman D, Stone J, Albanese CT, Bahado-Singh R, Ball RH, Bilaniuk L, Coleman B, Farmer D, Feldstein V, Harrison MR, Hedrick H, Livingston J, Lorenz RP, Miller DA, Norton ME, Polzin WJ, Robinson JN, Rychik J, Sandberg PL, Seri I, Simon E, Simpson LL, Yedigarova L, Wilson RD, Young B.  A prospective, randomized, multicenter trial of amnioreduction vs. selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome.  Am J Obstet Gynecol 2007; 197:396.

Levitt MA, Mak GZ, Falcone Jr. RA, Peña A.  Cloacal exstrophy - pull-through or permanent stoma?  A review of 53 patients.  J Pediatr Surg 2008; 43:164.

Inge TH, Zeller M, Harmon C, Helmrath M, Bean J, Modi A, Horlock M, Kalra M, Xanthakos S, Miller R, Akers R, Courcoulas A.  Teen -Longitudinal Assessment of Bariatric Surgery: Methodological features of the first prospective multicenter study of adolescent bariatric surgery.  J Pediatr Surg 2007; 42:1969.

Jafri M, Donnelly B, McNeal M, Ward, R, Tiao G, MAPK signaling contributes to rotaviral-induced cholangiocyte injury and viral replication. Surgery142(2) 192-201, 2007.

Rangel SJ, Martin CA, Brown RL, Garcia VF, Falcone RA.  Alarming trends in the improper use of motor-vehicle restraints in children: Implications for public policy and the development of race-based strategies for improving compliance.  J Pediatr Surg 2008; 43:200.               

Division Highlights

Dr. Timothy Crombleholme

Dr. Richard Falcone

Dr. Thomas Inge

Dr. Gregory Tiao

Division Collaboration

Collaboration with Pediatric Surgery; Hematology-Oncology

Collaborating Faculty: Dr. Timothy Crombleholme; Dr. Timothy Cripe

Division Publications

1. Alam S, Levitt MA, Sheldon CA, Pena A. The posterior sagittal approach for recurrent genitourinary pathology. J Urol. 2007; 178: 1668-71; discussion 1671.
2. Azizkhan RG. "Perinatal tumors." In: R Carachi, JL Grosfeld, AF Azmy, eds. The surgery of childhood tumors. Berlin: Springer-Verlag; 2008: 145-170.
3. Azizkhan RG, Crombleholme TM. Congenital cystic lung disease: contemporary antenatal and postnatal management. Pediatr Surg Int. 2008; 24: 643-57.
4. Bartosh SM, Ryckman FC, Shaddy R, Michaels MG, Platt JL, Sweet SC. A national conference to determine research priorities in pediatric solid organ transplantation. Pediatr Transplant. 2008; 12: 153-66.
5. Crombleholme TM, Shera D, Lee H, Johnson M, D'Alton M, Porter F, Chyu J, Silver R, Abuhamad A, Saade G, Shields L, Kauffman D, Stone J, Albanese CT, Bahado-Singh R, Ball RH, Bilaniuk L, Coleman B, Farmer D, Feldstein V, Harrison MR, Hedrick H, Livingston J, Lorenz RP, Miller DA, Norton ME, Polzin WJ, Robinson JN, Rychik J, Sandberg PL, Seri I, Simon E, Simpson LL, Yedigarova L, Wilson RD, Young B. A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol. 2007; 197: 396 e1-9.
6. Dasgupta R, Adams D, Elluru R, Wentzel MS, Azizkhan RG. Noninterventional treatment of selected head and neck lymphatic malformations. J Pediatr Surg. 2008; 43: 869-73.
7. Dasgupta R, Langer JC. Evaluation and management of persistent problems after surgery for Hirschsprung disease in a child. J Pediatr Gastroenterol Nutr. 2008; 46: 13-9.
8. Dasgupta R, Wales PW, Zuker RM, Fisher DM, Langer JC. The use of Surgisis for abdominal wall reconstruction in the separation of omphalopagus conjoined twins. Pediatr Surg Int. 2007; 23: 923-6.
9. Falcone RA, Jr., Daugherty M, Schweer L, Patterson M, Brown RL, Garcia VF. Multidisciplinary pediatric trauma team training using high-fidelity trauma simulation. J Pediatr Surg. 2008; 43: 1065-71.
10. Gordon A, Kozin ED, Keswani SG, Vaikunth SS, Katz AB, Zoltick PW, Favata M, Radu AP, Soslowsky LJ, Herlyn M, Crombleholme TM. Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation. Wound Repair Regen. 2008; 16: 70-9.
11. Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Molkentin JD. Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest. 2007; 117: 3198-210.
12. Inge T, Helmrath M, Vierra M, Ikramuddin S. Challenges of adolescent bariatric surgery: tips for managing the extremely obese teen. J Laparoendosc Adv Surg Tech A. 2008; 18: 157-69.
13. Inge TH. Childhood obesity--a problem of surgical proportions?. Nat Clin Pract Gastroenterol Hepatol. 2008; 5: 180-1.
14. Inge TH, Zeller M, Harmon C, Helmrath M, Bean J, Modi A, Horlick M, Kalra M, Xanthakos S, Miller R, Akers R, Courcoulas A. Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery. J Pediatr Surg. 2007; 42: 1969-71.
15. Ippisch HM, Inge TH, Daniels SR, Wang B, Khoury PR, Witt SA, Glascock BJ, Garcia VF, Kimball TR. Reversibility of cardiac abnormalities in morbidly obese adolescents. J Am Coll Cardiol. 2008; 51: 1342-8.
16. Jafri M, Alonso M, Kaul A, Dierig J, Racadio J, Inge T, Brown R, Ryckman F, Tiao G. Intraoperative manometry during laparoscopic Heller myotomy improves outcome in pediatric achalasia. J Pediatr Surg. 2008; 43: 66-70; discussion 70.
17. Jafri M, Donnelly B, McNeal M, Ward R, Tiao G. MAPK signaling contributes to rotaviral-induced cholangiocyte injury and viral replication. Surgery. 2007; 142: 192-201.
18. Kalra M, Mannaa M, Fitz K, Kumar S, Chakraborty R, Sheng X, Inge T. Effect of surgical weight loss on sleep architecture in adolescents with severe obesity. Obes Surg. 2008; 18: 675-9.
19. Levitt MA, Mak GZ, Falcone RA, Jr., Pena A. Cloacal exstrophy--pull-through or permanent stoma? A review of 53 patients. J Pediatr Surg. 2008; 43: 164-8; discussion 168-70.
20. Livingston JC, Lim FY, Polzin W, Mason J, Crombleholme TM. Intrafetal radiofrequency ablation for twin reversed arterial perfusion (TRAP): a single-center experience. Am J Obstet Gynecol. 2007; 197: 399 e1-3.
21. Livingston JC, Malik KM, Crombleholme TM, Lim FY, Sibai BM. Mirror syndrome: a novel approach to therapy with fetal peritoneal-amniotic shunt. Obstet Gynecol. 2007; 110: 540-3.
22. Mahller YY, Vaikunth SS, Ripberger MC, Baird WH, Saeki Y, Cancelas JA, Crombleholme TM, Cripe TP. Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors. Cancer Res. 2008; 68: 1170-9.
23. Martin C, Falcone RA, Jr.. Pediatric traumatic brain injury: an update of research to understand and improve outcomes. Curr Opin Pediatr. 2008; 20: 294-9.
24. Michelfelder E, Gottliebson W, Border W, Kinsel M, Polzin W, Livingston J, Khoury P, Crombleholme T. Early manifestations and spectrum of recipient twin cardiomyopathy in twin-twin transfusion syndrome: relation to Quintero stage. Ultrasound Obstet Gynecol. 2007; 30: 965-71.
25. Miller RJ, Xanthakos SA, Hillard PJ, Inge TH. Bariatric surgery and adolescent gynecology. Curr Opin Obstet Gynecol. 2007; 19: 427-33.
26. Oliveira C, Zamakhshary M, Abdallah MR, Miller SF, Langer JC, Wales PW, Dasgupta R. Lung torsion after tracheoesophageal fistula repair: a case report and review of literature. J Pediatr Surg. 2007; 42: E5-9.
27. Parvadia JK, Keswani SG, Vaikunth S, Maldonado AR, Marwan A, Stehr W, Erwin C, Uzvolgyi E, Warner BW, Yamano S, Taichman N, Crombleholme TM. Role of VEGF in small bowel adaptation after resection: the adaptive response is angiogenesis dependent. Am J Physiol Gastrointest Liver Physiol. 2007; 293: G591-8.
28. Rangel SJ, Martin CA, Brown RL, Garcia VF, Falcone RA, Jr.. Alarming trends in the improper use of motor vehicle restraints in children: implications for public policy and the development of race-based strategies for improving compliance. J Pediatr Surg. 2008; 43: 200-7.
29. Richter GT, Ryckman F, Brown RL, Rutter MJ. Endoscopic management of recurrent tracheoesophageal fistula. J Pediatr Surg. 2008; 43: 238-45.
30. Roehrig HR, Xanthakos SA, Sweeney J, Zeller MH, Inge TH. Pregnancy after gastric bypass surgery in adolescents. Obes Surg. 2007; 17: 873-7.
31. Ryckman FC, Bucuvalas JC, Nathan J, Alonso M, Tiao G, Balistreri WF. Outcomes following liver transplantation. Semin Pediatr Surg. 2008; 17: 123-30.
32. Sparling KW, Ryckman FC, Schoettker PJ, Byczkowski TL, Helpling A, Mandel K, Panchanathan A, Kotagal UR. Financial impact of failing to prevent surgical site infections. Qual Manag Health Care. 2007; 16: 219-25.
33. Stehr W, Farrell MK, Lucky AW, Johnson ND, Racadio JM, Azizkhan RG. Non-endoscopic percutaneous gastrostomy placement in children with recessive dystrophic epidermolysis bullosa. Pediatr Surg Int. 2008; 24: 349-54.

Grants, Contracts, and Industry Agreements

Crombleholme, T

Falcone, R

Garcia, V

Inge, T

Laurence, S

Tiao, G

Maldonado, A

Falcone, R

Inge, T