Cardiology

Division Details

Division Data Summary

Research and Training Details

Number of Faculty44
Number of Joint Appointment Faculty2
Number of Research Fellows4
Number of Support Personnel156
Direct Annual Grant Support$1,135,130
Direct Annual Industry Support$32,236
Peer Reviewed Publications121

Clinical Activities and Training

Number of Clinical Staff2
Number of Clinical Fellows14
Inpatient Encounters1,469
Outpatient Encounters16,765

Division Photo

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Significant Publications

Brescia ST, Rossano JW, Pignatelli R, Jefferies JL, Price JF, Decker JA, Denfield SW, Dreyer WJ, Smith O, Towbin JA, Kim JJ. Mortality and sudden death in pediatric left ventricular noncompaction in a tertiary referral center. Circulation. 2013 Jun 4;127(22):2202-8.
This article is the largest report ever published on left ventricular noncompaction (LVNC) in children. The frequency of this diagnosis is increasing the importance of defining risk factors for morbidity and mortality. Our publication delineates specific clinical criteria that are predictive of poor outcome. These criteria offer clinicians around the world guidance for management of children with LVNC. Furthermore, this study fills a void in the existing literature regarding this disease and will contribute to the substrate for cardiomyopathy guidelines in the future.

Division Publications

Cardiology Publications

  1. Alghamdi M, De Souza AM, White CT, Potts MT, Warady BA, Furth SL, Kimball TR, Potts JE, Sandor GG. Echo-Doppler assessment of the biophysical properties of the aorta in children with chronic kidney disease. Pediatr Cardiol. 2013; 34:1218-25.
  2. Allen KY, Goldstein BH, Pahl E, Schumacher KR, Gajarski RJ, Backer CL, Wax DF, Kaushal S, Gossett JG. Non-cameral coronary artery fistulae after pediatric cardiac transplantation: a multicenter study. J Heart Lung Transplant. 2012; 31:744-9.
  3. Anderson JB, Czosek RJ, Cnota J, Meganathan K, Knilans TK, Heaton PC. Pediatric syncope: national hospital ambulatory medical care survey results. J Emerg Med. 2012; 43:575-83.
  4. Anderson JB, Czosek RJ, Knilans TK, Marino BS. The effect of paediatric syncope on health-related quality of life. Cardiol Young. 2012; 22:583-8.
  5. Anderson JB, Czosek RJ, Knilans TK, Meganathan K, Heaton P. Postoperative Heart Block in Children with Common Forms of Congenital Heart Disease: Results from the KID Database. J Cardiovasc Electrophysiol. 2012; 23:1349-54.
  6. Anderson JB, Iyer SB, Schidlow DN, Williams R, Varadarajan K, Horsley M, Slicker J, Pratt J, King E, Lannon C. Variation in growth of infants with a single ventricle. J Pediatr. 2012; 161:16-21 e1; quiz 21 e2-3.
  7. Ashley EA, Hershberger RE, Caleshu C, Ellinor PT, Garcia JG, Herrington DM, Ho CY, Johnson JA, Kittner SJ, Macrae CA, Mudd-Martin G, Rader DJ, Roden DM, Scholes D, Sellke FW, Towbin JA, Van Eyk J, Worrall BB. Genetics and cardiovascular disease: a policy statement from the American Heart Association. Circulation. 2012; 126:142-57.
  8. Askenazi DJ, Selewski DT, Paden ML, Cooper DS, Bridges BC, Zappitelli M, Fleming GM. Renal replacement therapy in critically ill patients receiving extracorporeal membrane oxygenation. Clin J Am Soc Nephrol. 2012; 7:1328-36.
  9. Averin K, Uzark K, Beekman RH, 3rd, Willging JP, Pratt J, Manning PB. Postoperative assessment of laryngopharyngeal dysfunction in neonates after Norwood operation. Ann Thorac Surg. 2012; 94:1257-61.
  10. Bartos DC, Anderson JB, Bastiaenen R, Johnson JN, Gollob MH, Tester DJ, Burgess DE, Homfray T, Behr ER, Ackerman MJ, Guicheney P, Delisle BP. A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation. J Cardiovasc Electrophysiol. 2013; 24:562-9.
  11. Beekman RH, 3rd. Coarctation of the Aorta. In: HD Allen, DJ Driscoll, RE Shaddy, TF Feltes, eds. Moss & Adams' Heart Disease in Infants, Children and Adolescents: Including the Fetus and Young Adult. Philadelphia, PA: Lippincott Williams & Wilkins; 2012:1044-1060.
  12. Beekman RH, 3rd. FDA Clearance of Cardiac Devices for Children: A Primer and Call to Action. Congenital Cardiology Today. 2012; 10:1-7.
  13. Beekman RH, 3rd, Lannon C. The National Pediatric Cardiology Quality Improvement Collaborative. Neonatology Today. 2013; 8:1-5.
  14. Berger KA, Lynch J, Prows CA, Siegel RM, Myers MF. Mothers' perceptions of family health history and an online, parent-generated family health history tool. Clin Pediatr (Phila). 2013; 52:74-81.
  15. Brescia ST, Rossano JW, Pignatelli R, Jefferies JL, Price JF, Decker JA, Denfield SW, Dreyer WJ, Smith O, Towbin JA, Kim JJ. Mortality and sudden death in pediatric left ventricular noncompaction in a tertiary referral center. Circulation. 2013; 127:2202-8.
  16. Bridges BC, Selewski DT, Paden ML, Cooper DS, Zappitelli M, Fleming GM, Askenazi DJ. Acute Kidney Injury in Neonates Requiring ECMO. NeoReviews. 2012; 13:e428-433.
  17. Brown KL, Ichord R, Marino BS, Thiagarajan RR. Outcomes Following Extracorporeal Membrane Oxygenation in Children with Cardiac Disease. Pediatric Critical Care Medicine. 2013; 15:S73-S83.
  18. Burns KC, Nagarajan R, O. SF, Marino BS. Oncology. In: BS Marino, KS Fine, eds. Blueprints: Pediatrics. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:205-223.
  19. Cassedy A, Drotar D, Ittenbach R, Hottinger S, Wray J, Wernovsky G, Newburger JW, Mahony L, Mussatto K, Cohen MI, Marino BS. The impact of socio-economic status on health related quality of life for children and adolescents with heart disease. Health Qual Life Outcomes. 2013; 11:99.
  20. Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, Vandusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W. Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development. 2013; 140:1946-57.
  21. Chin C. Cardiac antibody-mediated rejection. Pediatr Transplant. 2012; 16:404-12.
  22. Cnota JF, Allen KR, Colan S, Covitz W, Graham EM, Hehir DA, Levine JC, Margossian R, McCrindle BW, Minich LL, Natarajan S, Richmond ME, Hsu DT, Pediatric Heart Network I. Superior cavopulmonary anastomosis timing and outcomes in infants with single ventricle. J Thorac Cardiovasc Surg. 2013; 145:1288-96.
  23. Cohen M, Ladinsky M, Marino BS. Gastroenterology. In: BS Marino, KS Fine, eds. Blueprints: Pediatrics. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:134-153.
  24. Cooper DS, Hirsch JC, Jacobs JJ. Pediatric Cardiac Extracorporeal Life Support. In: GM Annich, WR Lynch, G MacLaren, JM Wilson, RH Bartlett, eds. ECMO: Extracorporeal Cardiopulmonary Support in Critical Care. Ann Arbor: Extracorporeal Life Support Organization; 2012.
  25. Cooper DS, Prêtre R. Clinical management of pediatric ventricular assist devices. Pediatr Crit Care Med. 2013; 14:S27-36.
  26. Cooper DS, Thiagarajan RR, Almond CS, VanderPluym CJ, Buchholz H, Jacobs JP. Ventricular Assist Devices in Children. In: GM Annich, WR Lynch, G MacLaren, JM Wilson, RH Bartlett, eds. ECMO: Extracorporeal Cardiopulmonary Support in Critical Care. Ann Arbor: Extracorporeal Life Support Organization; 2012.
  27. Czosek RJ, Anderson J, Khoury PR, Knilans TK, Spar DS, Marino BS. Utility of ambulatory monitoring in patients with congenital heart disease. Am J Cardiol. 2013; 111:723-30.
  28. Czosek RJ, Anderson JB, Heaton PC, Cassedy A, Schnell B, Cnota JF. Staged palliation of hypoplastic left heart syndrome: trends in mortality, cost, and length of stay using a national database from 2000 through 2009. Am J Cardiol. 2013; 111:1792-9.
  29. Czosek RJ, Bonney WJ, Cassedy A, Mah DY, Tanel RE, Imundo JR, Singh AK, Cohen MI, Miyake CY, Fawley K, Marino BS. Impact of cardiac devices on the quality of life in pediatric patients. Circ Arrhythm Electrophysiol. 2012; 5:1064-72.
  30. Divanović A, Witte D, Michelfelder E. A fetus with hypoplastic left heart syndrome and tricuspid stenosis with evolving hydrops fetalis. Pediatr Cardiol. 2012; 33:1210-2.
  31. Elder D, Marino BS. Endocrinology. In: BS Marino, KS Fine, eds. Blueprints: Pediatrics. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:241-455.
  32. Fleming GM, Askenazi DJ, Bridges BC, Cooper DS, Paden ML, Selewski DT, Zappitelli M. A multicenter international survey of renal supportive therapy during ECMO: the Kidney Intervention During Extracorporeal Membrane Oxygenation (KIDMO) group. ASAIO J. 2012; 58:407-14.
  33. Frank LH, Bradshaw E, Beekman R, Mahle WT, Martin GR. Critical congenital heart disease screening using pulse oximetry. J Pediatr. 2013; 162:445-53.
  34. Frommelt PC, Gerstenberger E, Baffa J, Border WL, Bradley TJ, Colan S, Gorentz J, Heydarian H, John JB, Lai WW, Levine J, Lu JC, McCandless RT, Miller S, Nutting A, Ohye RG, Pearson GD, Wong PC, Cohen MS, Pediatric Heart Network I. Doppler flow patterns in the right ventricle-to-pulmonary artery shunt and neo-aorta in infants with single right ventricle anomalies: impact on outcome after initial staged palliations. J Am Soc Echocardiogr. 2013; 26:521-9.
  35. George-Abraham JK, Zimmerman SL, Hinton RB, Marino BS, Witte DP, Hopkin RJ. Tetrasomy 15q25.2 >qter identified with SNP microarray in a patient with multiple anomalies including complex cardiovascular malformation. Am J Med Genet A. 2012; 158A:1971-6.
  36. Ghanayem NS, Allen KR, Tabbutt S, Atz AM, Clabby ML, Cooper DS, Eghtesady P, Frommelt PC, Gruber PJ, Hill KD, Kaltman JR, Laussen PC, Lewis AB, Lurito KJ, Minich LL, Ohye RG, Schonbeck JV, Schwartz SM, Singh RK, Goldberg CS. Interstage mortality after the Norwood procedure: Results of the multicenter Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg. 2012; 144:896-906.
  37. Goldenberg P, Marino BS. Genetic Disorders. In: BS Marino, KS Fine, eds. Blueprints: Pediatrics. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:315-326.
  38. Goldstein BH, Hirsch R, Zussman ME, Vincent JA, Torres AJ, Coulson J, Ringel RE, Beekman RH, 3rd. Percutaneous balloon-expandable covered stent implantation for treatment of traumatic aortic injury in children and adolescents. Am J Cardiol. 2012; 110:1541-5.
  39. Grenier MA. Looking into an athlete's heart: Panacea or Pandora's box?. Future Cardiol. 2012; 8:805-7.
  40. Griffin AC, Strauss AW, Bennett MJ, Ernst LM. Mutations in long-chain 3-hydroxyacyl coenzyme a dehydrogenase are associated with placental maternal floor infarction/massive perivillous fibrin deposition. Pediatr Dev Pathol. 2012; 15:368-74.
  41. Guha IN, Bokhandi S, Ahmad Z, Sheron N, Cope R, Marshall C, Veldtman G. Structural and functional uncoupling of liver performance in the Fontan circulation. Int J Cardiol. 2013; 164:77-81.
  42. Gupta R, Marino BS, Cnota JF, Ittenbach RF. Finding the right distribution for highly skewed zero-inflated clinical data. Epidemiology Biostatistics and Public Health. 2013; 10:e8732-1-15.
  43. Gurvitz M, Valente AM, Broberg C, Cook S, Stout K, Kay J, Ting J, Kuehl K, Earing M, Webb G, Houser L, Opotowsky A, Harmon A, Graham D, Khairy P, Gianola A, Verstappen A, Landzberg M, Alliance for Adult Research in Congenital C, Adult Congenital Heart A. Prevalence and Predictors of Gaps in Care Among Adult Congenital Heart Disease Patients: HEART-ACHD (The Health, Education, and Access Research Trial). J Am Coll Cardiol. 2013; 61:2180-4.
  44. Hampl S, Demeule M, Eneli I, Frank M, Hawkins MJ, Kirk S, Morris P, Sallinen BJ, Santos M, Ward WL, Rhodes E. Parent perspectives on attrition from tertiary care pediatric weight management programs. Clin Pediatr (Phila). 2013; 52:513-9.
  45. Hanke SP, Gardner AB, Lombardi JP, Manning PB, Nelson DP, Towbin JA, Jefferies JL, Lorts A. Left ventricular noncompaction cardiomyopathy in Barth syndrome: an example of an undulating cardiac phenotype necessitating mechanical circulatory support as a bridge to transplantation. Pediatr Cardiol. 2012; 33:1430-4.
  46. Hinton RB. Genetics of Bicuspid Aortic Valve and Calcific Aortic Valve Disease. In: E Aikawa, ed. Calcific Aortic Valve Disease. Rijeka, Croatia: InTech; 2013:173-204.
  47. Hinton RB. Genetic and environmental factors contributing to cardiovascular malformation: a unified approach to risk. J Am Heart Assoc. 2013; 2:e000292.
  48. Hinton RB. Bicuspid aortic valve and thoracic aortic aneurysm: three patient populations, two disease phenotypes, and one shared genotype. Cardiol Res Pract. 2012; 2012:926975.
  49. Hollander SA, Addonizio LJ, Chin C, Lamour JM, Hsu DT, Bernstein D, Rosenthal DN. Abdominal complaints as a common first presentation of heart failure in adolescents with dilated cardiomyopathy. Am J Emerg Med. 2013; 31:684-6.
  50. Jayakumar C, Ranganathan P, Devarajan P, Krawczeski CD, Looney S, Ramesh G. Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury. PLoS One. 2013; 8:e58446.
  51. Jefferies JL, Goldstein SL. Cardiorenal syndrome: an emerging problem in pediatric critical care. Pediatr Nephrol. 2013; 28:855-62.
  52. Jefferies JL, Morales DL. Mechanical circulatory support in children: bridge to transplant versus recovery. Curr Heart Fail Rep. 2012; 9:236-43.
  53. Jodele S, Hirsch R, Laskin B, Davies S, Witte D, Chima R. Pulmonary arterial hypertension in pediatric patients with hematopoietic stem cell transplant-associated thrombotic microangiopathy. Biol Blood Marrow Transplant. 2013; 19:202-7.
  54. Kimball TR, Michelfelder EC. Echocardiography: Basic Principles and Imaging. In: HD Allen, DJ Driscoll, RE Shaddy, TF Feltes, eds. Moss & Adams' Heart Disease in Infants, Children and Adolescents: Including the Fetus and Young Adult. Philadelphia, PA: Lippincott Williams & Wilkins; 2012:134-171.
  55. Kirk S, Brehm B, Saelens BE, Woo JG, Kissel E, D'Alessio D, Bolling C, Daniels SR. Role of carbohydrate modification in weight management among obese children: a randomized clinical trial. J Pediatr. 2012; 161:320-7 e1.
  56. Knowles R, Veldtman G, Hickey EJ, Bradley T, Gengsakul A, Webb GD, Williams WG, McCrindle BW. Functional health status of adults with tetralogy of Fallot: matched comparison with healthy siblings. Ann Thorac Surg. 2012; 94:124-32.
  57. Knudson JD, Neish SR, Cabrera AG, Lowry AW, Shamszad P, Morales DL, Graves DE, Williams EA, Rossano JW. Prevalence and outcomes of pediatric in-hospital cardiopulmonary resuscitation in the United States: An analysis of the Kids' Inpatient Database*. Crit Care Med. 2012; 40:2940-4.
  58. Kreeger RN, Ramamoorthy C, Nicolson SC, Ames WA, Hirsch R, Peng LF, Glatz AC, Hill KD, Hoffman J, Tomasson J, Kurth CD. Evaluation of pediatric near-infrared cerebral oximeter for cardiac disease. Ann Thorac Surg. 2012; 94:1527-33.
  59. Lalani SR, Shaw C, Wang X, Patel A, Patterson LW, Kolodziejska K, Szafranski P, Ou Z, Tian Q, Kang SH, Jinnah A, Ali S, Malik A, Hixson P, Potocki L, Lupski JR, Stankiewicz P, Bacino CA, Dawson B, Beaudet AL, Boricha FM, Whittaker R, Li C, Ware SM, Cheung SW, Penny DJ, Jefferies JL, Belmont JW. Rare DNA copy number variants in cardiovascular malformations with extracardiac abnormalities. Eur J Hum Genet. 2013; 21:173-81.
  60. Learn CP, Holzer RJ, Daniels CJ, Torres AJ, Vincent JA, Moore JW, Armsby LB, Landzberg MJ, Bergersen L. Adverse events rates and risk factors in adults undergoing cardiac catheterization at pediatric hospitals-results from the C3PO. Catheter Cardiovasc Interv. 2013; 81:997-1005.
  61. Lorts A, Krawczeski CD, Marino BS. Cardiology. In: BS Marino, KS Fine, eds. Blueprints: Pediatrics. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:86-133.
  62. Lorts A, Schwanekamp JA, Baudino TA, McNally EM, Molkentin JD. Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-beta pathway. Proc Natl Acad Sci U S A. 2012; 109:10978-83.
  63. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA, 3rd, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De Leon FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, Memish ZA. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380:2095-128.
  64. Madsen NL, Drezner JA, Salerno JC. Sudden cardiac death screening in adolescent athletes: an evaluation of compliance with national guidelines. Br J Sports Med. 2013; 47:172-7.
  65. Madsen NL, Schwartz SM, Lewin MB, Mueller BA. Prepregnancy Body Mass Index and Congenital Heart Defects among Offspring: A Population-based Study. Congenit Heart Dis. 2013; 8:131-41.
  66. Madueme PC, Khoury PR, Urbina EM, Kimball TR. Predictors of exaggerated exercise-induced systolic blood pressures in young patients after coarctation repair. Cardiol Young. 2013; 23:416-22.
  67. Mahle WT, Lu M, Ohye RG, William Gaynor J, Goldberg CS, Sleeper LA, Pemberton VL, Mussatto KA, Williams IA, Sood E, Krawczeski CD, Lewis A, Mirarchi N, Scheurer M, Pasquali SK, Pinto N, Jacobs JP, McCrindle BW, Newburger JW. A predictive model for neurodevelopmental outcome after the Norwood procedure. Pediatr Cardiol. 2013; 34:327-33.
  68. Malatesta-Muncher R, Wansapura J, Taylor M, Lindquist D, Hor K, Mitsnefes M. Early cardiac dysfunction in pediatric patients on maintenance dialysis and post kidney transplant. Pediatr Nephrol. 2012; 27:1157-64.
  69. Marcus FI, Edson S, Towbin JA. Genetics of arrhythmogenic right ventricular cardiomyopathy: a practical guide for physicians. J Am Coll Cardiol. 2013; 61:1945-8.
  70. Marino BS. Evaluation of Quality of Life in Children and Adolescents with Congenital and Acquired Heart Disease. In: HD Allen, DJ Driscoll, RE Shaddy, TF Feltes, eds. Moss & Adams' Heart Disease in Infants, Children and Adolescents: Including the Fetus and Young Adult. Philadelphia, PA: Lippincott Williams & Wilkins; 2012:1608-1621.
  71. Marino BS, Lipkin PH, Newburger JW, Peacock G, Gerdes M, Gaynor JW, Mussatto KA, Uzark K, Goldberg CS, Johnson WH, Jr., Li J, Smith SE, Bellinger DC, Mahle WT. Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management: A Scientific Statement From the American Heart Association. Circulation. 2012; 126:1143-1172.
  72. Marino BS, Tibby SM, Hoffman GM. Resuscitation of the Patient with the Functionally Univentricular Heart. Current Pediatric Reviews. 2013; 9:148-157.
  73. Mathias A, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Qi M, Shimizu W, Towbin JA, Michael Vincent G, Wilde AA, Zhang L, Goldenberg I. Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome. Heart Rhythm. 2013; 10:720-5.
  74. Miyake CY, Webster G, Czosek RJ, Kantoch MJ, Dubin AM, Avasarala K, Atallah J. Efficacy of implantable cardioverter defibrillators in young patients with catecholaminergic polymorphic ventricular tachycardia: success depends on substrate. Circ Arrhythm Electrophysiol. 2013; 6:579-87.
  75. Molina KM, Garcia X, Denfield SW, Fan Y, Morrow WR, Towbin JA, Frazier EA, Nelson DP. Parvovirus B19 myocarditis causes significant morbidity and mortality in children. Pediatr Cardiol. 2013; 34:390-7.
  76. Moore J, Hegde S, El-Said H, Beekman R, 3rd, Benson L, Bergersen L, Holzer R, Jenkins K, Ringel R, Rome J, Vincent R, Martin G, Committee AIS. Transcatheter device closure of atrial septal defects: a safety review. JACC Cardiovasc Interv. 2013; 6:433-42.
  77. Mullally J, Goldenberg I, Moss AJ, Lopes CM, Ackerman MJ, Zareba W, McNitt S, Robinson JL, Benhorin J, Kaufman ES, Towbin JA, Barsheshet A. Risk of life-threatening cardiac events among patients with long QT syndrome and multiple mutations. Heart Rhythm. 2012; 10:378-82.
  78. Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black JA, Blencowe H, Blore JD, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha TS, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke CM, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter CE, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng AT, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Des Jarlais DC, Dharmaratne SD, Dherani M, Diaz-Torne C, Dolk H, Dorsey ER, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali SE, Erskine H, Erwin PJ, Espindola P, Ewoigbokhan SE, Farzadfar F, Feigin V, Felson DT, Ferrari A, Ferri CP, Fevre EM, Finucane MM, Flaxman S, Flood L, Foreman K, Forouzanfar MH, Fowkes FG, Fransen M, Freeman MK, Gabbe BJ, Gabriel SE, Gakidou E, Ganatra HA, Garcia B, Gaspari F, Gillum RF, Gmel G, Gonzalez-Medina D, Gosselin R, Grainger R, Grant B, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa YA, Hall W, Haring D, Haro JM, Harrison JE, Havmoeller R, Hay RJ, Higashi H, Hill C, Hoen B, Hoffman H, Hotez PJ, Hoy D, Huang JJ, Ibeanusi SE, Jacobsen KH, James SL, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas JB, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo JP, King CH, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Laden F, Lalloo R, Laslett LL, Lathlean T, Leasher JL, Lee YY, Leigh J, Levinson D, Lim SS, Limb E, Lin JK, Lipnick M, Lipshultz SE, Liu W, Loane M, Ohno SL, Lyons R, Mabweijano J, MacIntyre MF, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis DJ, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGill N, McGrath J, Medina-Mora ME, Meltzer M, Mensah GA, Merriman TR, Meyer AC, Miglioli V, Miller M, Miller TR, Mitchell PB, Mock C, Mocumbi AO, Moffitt TE, Mokdad AA, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch ME, Mwaniki MK, Naidoo K, Nair MN, Naldi L, Narayan KM, Nelson PK, Nelson RG, Nevitt MC, Newton CR, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer SB, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian JD, Rivero AP, Patten SB, Pearce N, Padilla RP, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips MR, Pierce K, Pion S, Polanczyk GV, Polinder S, Pope CA, 3rd, Popova S, Porrini E, Pourmalek F, Prince M, Pullan RL, Ramaiah KD, Ranganathan D, Razavi H, Regan M, Rehm JT, Rein DB, Remuzzi G, Richardson K, Rivara FP, Roberts T, Robinson C, De Leon FR, Ronfani L, Room R, Rosenfeld LC, Rushton L, Sacco RL, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel DC, Scott JG, Segui-Gomez M, Shahraz S, Shepard DS, Shin H, Shivakoti R, Singh D, Singh GM, Singh JA, Singleton J, Sleet DA, Sliwa K, Smith E, Smith JL, Stapelberg NJ, Steer A, Steiner T, Stolk WA, Stovner LJ, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor HR, Taylor JA, Taylor WJ, Thomas B, Thomson WM, Thurston GD, Tleyjeh IM, Tonelli M, Towbin JA, Truelsen T, Tsilimbaris MK, Ubeda C, Undurraga EA, van der Werf MJ, van Os J, Vavilala MS, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall DJ, Weinstock MA, Weintraub R, Weisskopf MG, Weissman MM, White RA, Whiteford H, Wiebe N, Wiersma ST, Wilkinson JD, Williams HC, Williams SR, Witt E, Wolfe F, Woolf AD, Wulf S, Yeh PH, Zaidi AK, Zheng ZJ, Zonies D, Lopez AD, AlMazroa MA, Memish ZA. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380:2197-223.
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Faculty, Staff, and Trainees

Faculty Members

Jeffrey A. Towbin, MD, FAAP, FACC, FAHA, Professor
Leadership Executive Co-Director, The Heart Institute; Director and Chief, Division of Cardiology
Research Interests Cardiomyopathy and genetics
Jeffrey B. Anderson, MD, MPH, Assistant Professor
Leadership Director, Value Delivery
Research Interests Syncope, nutritional failure in congenital heart disease, quality improvement
Robert H. Beekman, III, MD, Professor
Research Interests Cardiac catheterization and intervention, quality improvement
D. Woodrow Benson, MD, PhD, Adjunct
Research Interests Cardiovascular genetics
Castleberry Chesney, MD, Assistant Professor
Research Interests Immune deficiencies after and responses to cardiac transplantation
Clifford Chin, MD, Professor
Leadership Medical Director, Pediatric Heart Transplant Service
Research Interests Cardiomyopathy, heart failure, and cardiac transplantation
James F. Cnota, MD, Associate Professor
Leadership Director, Neonatal Cardiology
Research Interests Fetal cardiology, multicenter clinical trials
David S. Cooper, MD, MPH, Assistant Professor
Leadership Associate Medical Director, Cardiac Intensive Care Unit; Director, Cardiac ECMO Program
Research Interests Acute kidney injury in critical cardiac disease, anticoagulation on extracorporeal support, outcomes research
Richard J. Czosek, MD, Assistant Professor
Leadership Director, Cardiac Rhythm Device Management
Research Interests Cardiac pacing device and arrhythmia management in pediatric patients with congenital heart disease and cardiomyopathy
Allison Divanovic, MD, Assistant Professor
Research Interests Fetal echocardiography
Paula Goldenberg, MD, MSCE, MSW, FAAP, FACMG, Assistant Professor
Research Interests Cardiovascular genetics
Bryan H. Goldstein, MD, Assistant Professor
Research Interests Cardiac catheterization & intervention, hybrid therapies for congenital heart disease, single ventricle outcomes
Michelle Grenier, MD, Associate Professor
Leadership Director, 3 Dimensional Echocardiography
Research Interests Cardiomyopathy, heart failure, 3 Dimensional echocardiography, athletic screening in sudden cardiac death
Haleh Heydarian, MD, Assistant Professor
Leadership Medical Director, Heart Institute Single Ventricle Clinic
Research Interests Echocardiography Synchrony/Strain Imaging and Quality Improvement
Robert B. Hinton, MD, Associate Professor
Leadership Director, Heart Institute BioRepository
Research Interests Cardiovascular genetics and developmental biology
Russel Hirsch, MD, Associate Professor
Leadership Director, Pulmonary Hypertension Service; Director, Cardiac Cath and Intervention
Research Interests Cardiac Catheterization & Intervention, Device Development
Kan Hor, MD, Assistant Professor
Research Interests MRI technology to diagnose and follow heart disease, in particular DMD cardiomyopathy
Ilias Iliopoulos, MD, Assistant Professor
Research Interests Hemodynamic management and use of inotropes in cardiac intensive care
Holly M. Ippisch, MD, MS, FAAP, Assistant Professor
Research Interests Cardiovascular effects of pediatric obesity; cardiovascular effects of exercise; non-invasive cardiac imaging
John Lynn Jefferies, MD, MPH, FACC, FAAP, Associate Professor
Leadership Director, Advanced Heart Failure & Cardiomyopathy; Co-Director, CV Genetics
Research Interests Cardiomyopathy, Heart Failure, Cardiovascular Genetics and drug trials
Thomas R. Kimball, MD, Professor
Leadership Medical Director, Heart Institute
Research Interests Echocardiography, ventricular function, cardiovascular effects of obesity and type II diabetes
Shelley Kirk, PhD, RD, LD, Associate Professor
Research Interests The efficacy, safety and feasibility of interventions for the management of pediatric overweight and obesity
Timothy Knilans, MD, Professor
Leadership Director, Clinical Cardiac Electrophysiology; Director, Pediatric Cardiac Electrophysiology Fellowship; Director, Cardiac Exercise Laboratory
Research Interests Identification and risk stratification of causes of sudden death
Catherine Krawczeski, MD, Associate Professor
Leadership Director, Heart Institute Quality Improvement and Clinical Effectiveness; Co-Director, Center for Acute Care Nephrology
Research Interests Cardiac surgery-associated acute kidney injury, cardiorenal syndromes, biomarkers, quality improvement
Christopher Learn, MD, Assistant Professor
Leadership Co-Director, Adolescent and Adult Congenital Cardiology Fellowship Program
Research Interests Non-invasive imaging in congenital heart disease; adolescent/young adult transition care for persons with congenital heart disease; heart disease in pregnancy
Cong Liu, PhD, Assistant Professor
Leadership Associate Director of HIDL
Research Interests Genetic etiology of cardiomyopathy, congenital heart disease and cardiovascular diseases. New technology development in clinical genetic testing and clinical viral testing
Angela Lorts, MD, Assistant Professor
Leadership Director, Ventricular Assist Device Program
Research Interests Heart failure and myocardial remodeling
Madsen Nicolas, MD, Assistant Professor
Peace Madueme, MD, MS, Assistant Professor
Research Interests 3D Heart Modeling; Echo/MRI Quantification
Bradley S. Marino, MD, MPP, MSCE, Associate Professor
Leadership Director, Heart Institute Research Core; Director, Heart Institute Neurodevelopmental Clinic
Research Interests Outcomes Research
Erik Michelfelder, MD, Associate Professor
Leadership Co-Director, Heart Institute Imaging Service; Director, Fetal Heart Program
Research Interests Fetal cardiology and echocardiography
David Nelson, MD, PhD, Professor
Leadership Medical Director, CICU
Research Interests Inflammatory injury after cardiac surgery, endocrine dysfunction in critical illness
Enkhsaikhan Purevjav, MD, PhD, Assistant Professor
Research Interests Genetics of Cardiovascular Disease
Pirouz Shamszad, MD, Assistant Professor
Research Interests Patient outcomes and quality improvement in pediatric cardiac intensive care
Robert Siegel, MD, Professor
Leadership Medical Director, The Center for Better Health and Nutrition
David Spar, MD, Assistant Professor
Research Interests Pediatric and congenital electrophysiology
Joshua James Sticka, MD, Assistant Professor
Leadership Co-Director, Heart Institute Resident & Medical Student Education
Research Interests Non-invasive cardiac imaging; myocardial mechanics
Arnold Strauss, MD, Professor
Leadership BK Rachford Professor and Chair, Department of Pediatrics, University of Cincinnati College of Medicine; Director, Cincinnati Children's Research Foundation; Chief Medical Officer, Cincinnati Children's Hospital Medical Center
Michael Taylor, MD, PhD, Assistant Professor
Leadership Director of Advanced Imaging Innovation and Cardiac MRI (CMR); Co-Director, The Heart Institute Imaging Service
Research Interests Non-invasive study of cardiovascular physiology and metabolism; Pre-clinical imaging of cardiomyopathy models with cardiac MR and positron emission tomography
Elaine Urbina, MD, MS, Associate Professor
Leadership Director, Preventive Cardiology
Research Interests Non-invasive assessment of vascular structure and function and relationship to CV risk factors, obesity, diabetes, renal disease and sleep disorders. Treatment of high blood pressure and cholesterol
Gruschen Veldtman, MBChB, FRCP, Professor
Leadership Associate Director, AACHD Program; Inpatient Medical Director, AACHD Program
Research Interests The Fontan circulation and end-organ damage; risk stratification in high-risk pregnancy; pulmonary hypertension
Gary Webb, MD, FRCP(C), FACC, FAHA, Professor
Leadership Director, Adolescent and Adult Congenital Heart Disease Program
Research Interests Adolescent and adult congenital heart disease
Ivan Wilmot, MD, Assistant Professor
Research Interests Quality of life in children with heart failure, transplant, and those requiring mechanical circulatory support
Wenying Zhang, MD, PhD, FACMG, Assistant Professor
Leadership Associate Director, Heart Institute Diagnostic Laboratory
Research Interests Clinical molecular genetics; molecular genetic diagnosis of heritable cardiovascular disease; molecular diagnosis of viral infection of the heart

Joint Appointment Faculty Members

Jeanne James, MD, Associate Professor (Molecular Cardiovascular Biology)
Research Interests Manifestations and etiologies of misfolded protein response and echocardiography
Stephanie Ware, MD, Associate Professor (Molecular Cardiovascular Biology)
Research Interests Cardiovascular Genetics

Clinical Staff Members

  • Lisa Lee, MD
  • Chad Connor, MD

Trainees

  • Catherine Allen, MD, PL4, A.I. duPont Children's
  • Konstantin Averin, MD, PL4, Cincinnati Children's Hospital/University of Cincinnati
  • Joshua Daily, MD, PL4, Cincinnati Children's Hospital/University of Cincinnati
  • Karine Guerrier, DO, PL4, Cleveland Clinic
  • Sam Hanke, MD, PL7, Cincinnati Children's Hospital/University of Cincinnati
  • Anne-Cecile Huby, PhD, Pierre and Marie Curie University, France
  • Varun Krishnamurthy, BS, University of Cincinnati
  • David Kwiatkowski, MD, PL5, Cincinnati Children's Hospital/University of Cincinnati
  • Benjamin Landis, MD, PL5, Columbia University
  • Sarkies Ruben Mattheus Martherus, PhD, Maastricht University, The Netherlands
  • Ryan Moore, MD, PL5, Cincinnati Children's Hospital/University of Cincinnati
  • Charu Munjal, PhD, University of Louisville
  • Thomas Ryan, MD,PhD, PL7, Cincinnati Children's Hospital/University of Cincinnati
  • Michael Seckeler, MD, PL7, University of Virginia
  • Chistopher Statile, MD, PL7, Cincinnati Children's Hospital/University of Cincinnati
  • Aashoo Tandon, MD, PL5, Cincinnati Children's Hospital/University of Cincinnati
  • Tamara Thomas, MD, PL6, Vanderbilt University
  • Chet Villa, MD, PL6, Cincinnati Children's Hospital/University of Cincinnati

Division Collaboration

Adolescent Medicine » Laurie A. Mitan, MD
We explored QT prolongation in adolescent patients admitted with eating disorders. We analyzed associated factors leading to QT prolongation as well as QT prolongation as a prognostic indicator of outcome and disease severity.
Allergy & Immunology » Kimberly A. Risma, MD, PhD
Studying immune profiling, especially thymic markers, in patients who have received cardiac transplants and correlation with rates of infection, rejection, and death.
Behavioral Medicine & Clinical Psychology; Center for Adherence & Self-Management » Dean W. Beebe, PhD and Dennis D. Drotar, PhD
Studying the impact of neurodevelopmental outcomes on quality of life on complex CHC survivors.
Behavioral Medicine & Clinical Psychology » Michelle M. Ernst, PhD and Carrie Piazza-Waggoner, PhD
Studying psychosocial factors that predict quality of life in congenital heart disease surgical survivors.
Biostatistics & Epidemiology » Jessica Woo, MHSA, PhD
This collaboration stems from shared interests in growth as a measure of health in the pediatric population. Specifically, we identified growth abnormalities in the fetus with hypoplastic left heart. The project was novel by utilizing fetal ultrasound measurement to understand growth trajectory.
Biostatistics & Epidemiology » Jessica Woo, MHSA, PhD
Studying cardiovascular morbidity and mortality after 40 years follow-up in international cohorts.
Bone Marrow Transplantation & Immune Deficiency » Stella M. Davies, MBBS, PhD, MRCP
This collaboration focuses on the detection of chem-induced cardiotoxicity in the BMT population as well as those exposed to anthracyclines. We are seeing all patients in referral as well as performing novel imaging to detect cardiac involvement.
Center for Acute Nephrology » Stuart Goldstein, MD and Prasad Devarajan, MD
Collaboration on studies of acute kidney injury in cardiac patients, including patients with heart failure, Cardiorenal syndrome, and following cardiopulmonary bypass.
Center for Acute Nephrology » Stuart Goldstein, MD
Studying the impact of hybrid procedure for HLHS on AKI and the incidence of CKD in patients experiencing AKI after CPB.
Center for Acute Nephrology » Stuart Goldstein, MD
Studying the association of biomarkers and cardiac output in Fontan survivors.
Critical Care Medicine » Derek Wheeler, MD
Impedance pressure regulatory device. A novel study in pediatric critical care medicine: basic science and clinical evidence.
Endocrinology » Lawrence M. Dolan, MD and Amy Shah, MD
We are investigating the effects of diabetes on the cardiovascular system, specifically the progression of atherosclerosis in youth with obesity and T2DM and arterial stiffness in T1DM.
Endocrinology » Lawrence M. Dolan, MD
Studying Vitamin D levels and arterial stiffness.
Endocrinology » Philippe F. Backeljauw, MD and Sarah Lawson, MD
Studying arterial stiffness in Turner syndrome.
Endocrinology » Amy Shah, MD
Studying arterial Stiffness & HDL proteomics, as well as cerebrovascular and arterial change in T2DM.
Endocrinology » Nancy A. Crimmins, MD
We are researching the incidence of elevated left ventricular mass in severely obese toddlers and preschoolers.
Experimental Hematology and Cancer Biology-Molecular Genetics » Punam Malik, MD
Studying cardiovascular complications in sickle cell disease.
Fetal Care Center » Mounira Habli, MD
This collaboration stems from the multidisciplinary team that provides clinical care in the FCC. Specifically, we looked at the use of fetal echocardiography to guide clinical decision making in patients with high output cardiac lesions.
Gastroenterology, Hepatology & Nutrition » Stavra A. Xanthakos, MD, MS and Maisam A. Abu-El-Haija, MD
We are researching the presentation and management of hypertriglyceridemia-induced pancreatitis in children at Cincinnati Children’s.
Gastroenterology, Hepatology & Nutrition » Kathleen M. Campbell, MD
Magnetic resonance elastography of the liver in patients post-Fontan procedure: feasibility and preliminary results.
Gastroenterology, Hepatology & Nutrition » John C. Bucuvalas, MD and James E. Heubi, MD
This is a clinical research study investigating cirrhotic cardiomyopathy in ESLD and liver transplantation.
Hematology » Ralph A. Gruppo, MD
This collaboration focuses on evaluating predictors of BT shunt occlusion assessing for hematologic predictors.
Hematology; Pharmacy; Pediatric Surgery » Joseph S. Palumbo, MD, Alexander A. Vinks, PharmD, PhD, FCP, and Jason S. Frischer, MD
We studied the effect of Antithrombin 3 on anticoagulation during mechanical circulatory support.
Human Genetics » Nancy Doan Leslie, MD
Studying outcomes of patients with fatty acid oxidation disorders.
Human Genetics » Gregory A. Grabowski, MD and Robert J. Hopkin, MD
This collaboration focuses on clinical investigation of patients with MPS and related cardiovascular disease characterization and treatment strategies.
James M. Anderson Center for Health Systems Excellence » Carole Lannon, MD, MPH
The National Pediatric Cardiology Quality Improvement Collaborative is a Learning Network of 50 pediatric cardiology centers working together and with families to improve the quality of life for children with complex congenital heart disease.
Neonatology and Pulmonary Biology » Christina J. Valentine, MD
Studying fish oil supplementation in pregnancy.
Neonatology and Pulmonary Biology » Henry T. Akinbi, MD
A case report of neonatal long QT interval in a child with a metabolic syndrome.
Nephrology » Mark M. Mitsnefes, MD
We are investigating the effects of chronic kidney disease on the cardiovascular system, specifically arterial stiffness in CKD.
Nephrology » David K. Hooper, MD, MS
Studying blood pressure in CKD.
Nephrology » Jens W. Goebel, MD
Assessing the prevalence of aortopathy in end stage renal disease.
Nephrology » Jens W. Goebel, MD and David K. Hooper, MD, MS
Assessing impact of kidney transplantation on aortopathy.
Neurology » Brenda Wong, MD, MBBS
This collaboration focuses on the DMD population, specifically the development of a multidisciplinary clinic as well as ongoing clinical trials.
Neurology » Andrew D. Hershey, MD, PhD, FAHS
CHAMP (Childhood and Adolescent Migraine Prevention) Study. The study is a multicenter study with up to 40 centers enrolling 675 participants. We are reading all of the electrocardiograms for the study and providing cardiology support.
Pediatric Radiology » Janaka P. Wansapura, PhD
Studying cardiac MRI imaging and phenotype correlation in animal models of cardiomyopathies.
Pediatric Radiology » Patrick Winter, PhD
Studying the utilization of novel experimental MRI contrast agent to non-invasively detect apoptotic cells in the heart.
Pediatric Radiology; Gastroenterology, Hepatology & Nutrition » Daniel J. Podberesky, MD, Daniel B. Wallihan, MD, and Kathleen M. Campbell, MD
Studying the association of magnetic resonance elastography-determined liver stiffness with cardiac function after Fontan palliation.
Pediatric Surgery » Thomas H. Inge, MD, PhD
Conducting a comprehensive follow-up study of adolescent bariatric surgery at 5+ years post-operatively. The goal is to compare the long-term medical and psychosocial outcomes of surgical and non-surgical management of adolescents with severe obesity. This long-term is designed to provide the first systematic prospective data collection for a cohort of severely obese adolescents over a 5+ year period.
Pediatric Surgery » Jason S. Frischer, MD
We studied the outcome of multi-run ECMO.
Pharmacy; Center for Acute Nephrology » Alexander A. Vinks, PharmD, PhD, FCP and Stuart Goldstein, MD
Studying the effect of AKI on milrinone pharmacokinetics.
Pulmonary Medicine » Raouf S. Amin, MD
Studying arterial structure function in sleep apnea.
Pulmonary Medicine » Hemant Sawnani, MD
This collaboration focuses on the development of an integrated neuromuscular program as well as clinical research activities characterizing cardio-pulmonary interactions in DMD.
Sports Medicine » Nicholas M. Edwards, MD, MPH
Studying physical activity and cardiovascular risk factors in youth.

Grants, Contracts, and Industry Agreements

Cardiology Grants

Grant and Contract AwardsAnnual Direct

Cnota, J / Krawczeski, C

Pediatric Heart Network Prairieland Consortium
U10 HL 10967309/01/11-06/30/16$367,500
The Relationship of Family Factors to Developmental and Psychosocial Outcomes in Children with Hypoplastic Left Heart Syndrome
U01 HL 06827001/09/12-01/08/14$1,200
Trial of Beta Blocker vs Angiotensin II Receptor Blocker Therapy in Individuals with Marfan Syndrome
U01 HL 06827005/05/11-12/31/14$1,570

Ippisch, H

Effects of Dietary Fat and Exercise Challenges in Obese Children
K23 HL 09117409/01/08-07/31/13$124,500

Jefferies, j

Heart Failure Pediatric Cardiology Fellowship Program
07/01/12-06/30/12$15,000

Kimball, T

Chronic Kidney Disease in Children
U01 DK 06614308/01/08-07/31/13$60,996

Marino, B

Transitional Telehealth Homecare: REACH
R01 NR 00209309/21/11-06/30/16$86,360
Understanding Mechanisms of Fontan Failure and Key Predictors for Patient Outcome
R01 HL 09825202/01/10-01/31/14$16,667

Michelfelder, E

Hypoplastic Left Heart Syndrome: Expression of RHD in the Fetus
R01 HL 09863405/15/11-12/31/14$34,672

Moore, V

Quantitative Non-Invasive Assessment of Right Ventricular Function Using Global Longitudinal Strain and TAPSE in a Pre-Clinical Setting
06/01/13-05/31/14$22,727

Siegel, R

The Health Effects of a Blueberry Enriched Diet on Obese Children: A Feasibility Study
WBANA-Siegel11/01/12-10/31/13$30,000

Towbin, J

Biomarkers in Pediatric Cardiomyopathy
R01 HL 10909008/06/12-07/31/16$34,637

Urbina, E

Accelerated CV Aging in Youth Related to CV Risk Factor Clusters
R01 HL 10559101/01/11-12/31/15$339,301
Current Year Direct$1,135,130
Industry Contracts

Beekman, R

$1,186

Chin, C

$24,623

Hirsch, R

$6,427
Current Year Direct Receipts$32,236
Total$1,167,366