Critical Care Medicine
Division Data Summary
Research and Training Details
|Number of Faculty||11|
|Number of Support Personnel||20|
|Direct Annual Grant Support||$844,327|
|Direct Annual Industry Support||$15,490|
|Peer Reviewed Publications||22|
Clinical Activities and Training
|Number of Clinical Staff||10|
|Number of Clinical Fellows||14|
|Number of Other Students||1|
Row 1: H Wong, B Zingarelli, E Stalets, B Varisco
Row 2: S Poynter Wong, R Chima, D Wheeler, K Tegtmeyer, L Doughty
LifeCenter’s Champions for Life Award
Sue Poynter Wong, MD, was awarded the LifeCenter’s Champions for Life award on November 13, 2012. She was nominated in particular for her collaboration and work with one of our donor families. Her kind and empathetic care for her patient and this family was recognized, as was her tireless effort to preserve all options for donation. With the compassionate care provided in our PICU and the support and commitment from Sue, four lives were saved through the gift of organ donation from this patient and her family.
Trustee Award & Procter Scholar (TAPS) Program
Brian Varisco, MD, was awarded the Procter Scholar Program Award on December 12, 2012. The goal of the Procter Scholar Program is to support highly skilled pediatricians with a strong commitment to pursuing a career in academic research. Funds will support MD or MD/PhD pediatric fellows who are transitioning to a faculty appointment, with the goal of transitioning to a National Institutes of Health K-level award or K-level equivalent awards from foundations. Varisco has shown a strong commitment to pursuing a career in academic research, a record of accomplishment in research, along with a well-defined scientific research plan.
Leadership Changes in Critical Care Medicine
Congratulations to Derek Wheeler, MD, on his appointment this year to Associate Chief of Staff and to Erika Stalets, MD, on her appointment to Medical Director of the Division of Critical Care Medicine.
Critical Care Medicine Publications
- End-of-Life Care in Pediatrics: Ethics, Controversies, and Optimizing the Quality of Death. Pediatr Clin North Am. 2013; 60:725-39..
- Acute Kidney Injury Based on Corrected Serum Creatinine Is Associated With Increased Morbidity in Children Following the Arterial Switch Operation. Pediatr Crit Care Med. 2013; 14:e218–e224., , , , , .
- Renal angina: An emerging paradigm to identify children at risk for acute kidney injury. Pediatric Nephrology. 2012; 27:1067-1078., , , .
- Improving situation awareness to reduce unrecognized clinical deterioration and serious safety events. Pediatrics. 2013; 131:e298-308., , , , , , , , , , , , , , , .
- Advances in critical care of the pediatric hematopoietic stem cell transplant patient. Pediatr Clin North Am. 2013; 60:689-707., , .
- Improved outcomes for stem cell transplant recipients requiring pediatric intensive care. Pediatr Crit Care Med. 2012; 13:e336-42., , , , , , .
- Pediatric sepsis: challenges and adjunctive therapies. Crit Care Clin. 2013; 29:203-22., .
- Pulmonary arterial hypertension in pediatric patients with hematopoietic stem cell transplant-associated thrombotic microangiopathy. Biol Blood Marrow Transplant. 2013; 19:202-7., , , , , .
- Short-term high fat feeding increases organ injury and mortality after polymicrobial sepsis. Obesity (Silver Spring). 2012; 20:1995-2002., , , , , .
- Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Galpha(i2) protein. Inflammation. 2012; 35:1611-7., , , , , , .
- A Survey of Stated Physician Practices and Beliefs on the Use of Steroids in Pediatric Fluid and/or Vasoactive Infusion-Dependent Shock. Pediatr Crit Care Med. 2013; 14:462–466., , , , , , .
- Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality. Am J Respir Crit Care Med. 2013; 187:967-76., , , .
- Quality improvement initiative to reduce serious safety events and improve patient safety culture. Pediatrics. 2012; 130:e423-31., , , , , , , , , .
- Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis. Pediatr Crit Care Med. 2012; 13:e323-9., , , .
- Pediatric sepsis: preparing for the future against a global scourge. Curr Infect Dis Rep. 2012; 14:503-11., , , .
- The evolving model of pediatric critical care delivery in North America. Pediatr Clin North Am. 2013; 60:545-62., , .
- Care of the critically ill pediatric patient. Pediatr Clin North Am. 2013; 60:xv-xvi..
- An after action report of drotrecogin alpha (activated) and lessons for the future*. Pediatr Crit Care Med. 2012; 13:692-4..
- High-reliability emergency response teams in the hospital: improving quality and safety using in situ simulation training. BMJ Qual Saf. 2013; 22:507-14., , , , .
- Genome-wide expression profiling in pediatric septic shock. Pediatr Res. 2013; 73:564-9..
- Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children. Crit Care. 2012; 16:R213., , , , , , , , , , , , , , , , , , , , .
- The pediatric sepsis biomarker risk model. Crit Care. 2012; 16:R174., , , , , , , , , , , , , , , , , , , , , , , .
Faculty, Staff, and Trainees
- Hector Wong, MD, Professor
- Leadership Director
- Research Interests Septic shock, Genomics, Biomarkers
- Ranjit Chima, MD, Assistant Professor
- Research Interests Bone Marrow Transplantation-Associated Critical Illness
- Lesley Doughty, MD, Associate Professor
- Leadership Fellowship Director
- Research Interests Sepsis, viral infections & mechanical ventilation
- Jennifer Kaplan, MD, MS, Associate Professor
- Research Interests Sepsis, obesity and inflammation
- Sue E. Poynter, MD, Assistant Professor
- Leadership Medical Director Division of Respiratory Care; Associate Director Pediatric Residency Training Program
- Research Interests Medical education, residency & fellowship training
- Erika Stalets, MD, Instructor
- Leadership Medical Director
- Research Interests Quality improvement, patient safety and sepsis
- Ken Tegtmeyer, MD, Professor
- Leadership Chair Code Committee
- Research Interests Multimedia Medical Education
- Rajit Basu, MD, Assistant Professor
- Research Interests Phenotype and recognition of kidney injury, end of life care
- Derek S. Wheeler, MD, Associate Professor
- Leadership Associate Chief of Staff
- Research Interests Patient safety, healthcare administration
- Basilia Zingarelli, MD, Ph.D., Associate Professor
- Research Interests Sepsis, hemorrhage and ischemia and reperfusion injury
- Brian Varisco, MD, Instructor
- Research Interests Mechanisms of lung development, repair and regeneration
Joint Appointment Faculty Members
- Bradley Marino, MD, Associate Professor (Cardiology)
- Research Interests Long-term outcomes in children and adolescents with CHD, Resuscitation of children with CHD
- Kamal Abulebda, MD, PL-6, University of Aleppo, Syrian Republic
- Aaron Gardner, MD, PL-7, St. George's University
- William Hanna, MD, PL-7, University of Kentucky College of Medicine
- Shilpa Shah, MD, PL-7, The University of Texas Medical Branch
- Danielle Webster, MD, PL-6, University of Missouri - Kansas City
- Matthew Alder, MD, PL-5, University of Alabama School of Medicine
- Theodore DeMartini, MD, PL-5, University of Texas Medical Branch
- Hammad Ganatra, MD, PL-4, Aga Khan Medical College
- Katja Gist, MD, PL-8, University of New England College of Osteopathic Medicine
- Yu Inata, MD, PL-4, Osaka City University
- Laura Kitzmiller, MD, PL-4, Wayne State University School of Medicine
- Travis Langner, MD, PL-5, University of Kansas School of Medicine
- Mary Sandquist, MD, PL-4, Ohio State University College of Medicine
- Claire Stewart, MD, PL-4, Ohio State University College of Medicine
Grants, Contracts, and Industry Agreements
Critical Care Medicine Grants
|Grant and Contract Awards||Annual Direct|
|PPAR gamma in Pediatric Sepsis and the Inflammatory Response in Obesity|
|K08 GM 093135||06/01/10-05/31/14||$115,250|
|Therapeutic Hypothermia after Pediatric Cardiac Arrest|
|U01 HL 094345||09/01/09-02/28/14||$6,002|
|MMP-8 as a Novel Therapeutic Target in Sepsis|
|R01 GM 096994||04/01/11-03/31/15||$183,350|
|Stratification of Pediatric Septic Shock|
|R01 GM 099773||08/07/12-06/30/16||$243,861|
|PPARgamma and PPARgamma Agonists in Septic Shock|
|R01 GM 067202||09/14/12-06/30/16||$254,894|
|Role of Eicosanoids in Shock|
|R01 GM 027673||07/01/12-03/31/16||$22,128|
|Multi-Center Trial of Limiting PGY 2&3 Resident Work Hours in the PICU|
|U01 HL 111478||9/15/12-5/31/17||$18,842|
|Current Year Direct||$844,327|
|Current Year Direct Receipts||$15,490|