Academic Collaboration with Department of Pediatrics, College of Medicine in Malawi
An agreement has been completed to provide faculty and fellows to assist with the pediatric training of third-year medical students in Malawi. Our faculty from Emergency Medicine and other divisions will be involved in bedside clinical teaching, as well as formal lectures to 88 medical students in four groups each year in their pediatric clinical clerkship at Kamuzu Central Hospital in Lilongwe, Malawi. We believe that this collaborative effort will encourage more Malawian medical students to pursue pediatrics. We will continue to work with faculty colleagues at KCH to improve care in the general and neonatal wards. In collaboration with Dr. Mlotha, the Head of Pediatrics, we are designing research projects to assess outcomes of patients admitted to the emergency ward. To support this new program, Cincinnati Children’s has arranged local housing and transportation in Lilongwe.
Effect of influenza vaccine in pregnancy on fetal outcomes
Dr. Mark Steinhoff, with colleagues in Emory University, analyzed the effect of receipt of pandemic influenza vaccine in 2009-10 among 3,227 women, of whom 1,125 received vaccine. The analysis showed that mothers who received the pandemic vaccine had 37% lower odds of having preterm infants, and the mean birth weight of infants of vaccinated mothers was 45% greater than that of the unvaccinated mothers.
Children with influenza in China
Drs. Steven Black and Mark Steinhoff, working with colleagues in Fudan University, analyzed data from 480 children hospitalized with laboratory-proven influenza between 2005 and 2009. They described the common clinical characteristics, as well as the cost of influenza-related hospitalization. This was the first study of the cost of laboratory-proven influenza hospitalization in China, showing that there is potential for the use of influenza vaccine in children to reduce medical care costs.
Decreased Antibody Response to Influenza Vaccine in Pregnant Women
Elizabeth Schlaudecker, MD, MPH, studied the immunologic response to influenza immunization in pregnant women compared to non-pregnant women. Because the antibody responses (hemagglutination inhibition titers) were significantly decreased in pregnant women compared to non-pregnant women after immunization, Dr. Schlaudecker is currently investigating the IgG isotype responses to influenza immunization in Dr. Sing Sing Way’s laboratory with the mentorship of Dr. Fred Finkelman in the Division of Cellular and Molecular Immunology.
Award for presentation of vitamin D supplementation study in the UAE
A poster presentation on vitamin D supplementation during pregnancy in the UAE received the best poster award during the 7th Dubai International Conference for Medical Sciences. December 2012, Dubai, UAE.
Renewal and expansion of Nurturing Children’s Development program
The Nurturing Children's Development Program, Cincinnati Children’s P&G partnership funded by the Pampers Brand, has been renewed for another three years starting July 1, 2013 to fund research scholars and observers from China, Latin America (Brazil) and Africa (Nigeria). The program will sponsor four research scholars, as well as 18 observers from these countries. The research scholars will spend 12 months in research at Cincinnati Children’s and each observer will complete two-month clinical observer programs. It is anticipated that additional funding will be provided for a research scholar from Singapore, the current headquarters of P&G Global Baby Care which funds the program.
The Risk of Narcolepsy following Adjuvanted Pandemic Influenza Vaccine
In this US CDC funded study, Dr. Steven Black and colleagues will evaluate the risk of narcolepsy following adjuvanted influenza vaccines. Three such vaccines were used during the 2009-2010 pandemic and one was associated with an increased risk of narcolepsy in children in several European studies. The goal of this project is to expand the scope of prior studies to include the other two adjuvanted vaccines by performing studies in Brazil, Taiwan, Canada, Israel, the Netherlands, Spain and Argentina. The results of this study will inform the future use and selection of adjuvants for future pandemics.