Alexander A. Vinks, PharmD, PhD, FCP
Sander Vinks, PharmD, PhD received a grant from the Perinatal Institute’s Pilot and Feasibility Program for Research in Perinatal Biology and Health to develop a rapid bedside test for the measurement of morphine in blood. The procedure is as simple as glucose monitoring in diabetes patients: a single drop of blood is analyzed for morphine within minutes. Next, results are entered into a web-based application for pharmacokinetically-guided individualized dosing. This will allow clinicians to tailor morphine amount to each neonate’s needs.
Dr. Vinks is one of the inventors on US Patent 8,589,175B2 – Optimization and Individualization of Medication Selection and Dosing which was granted on November 19, 2013. Cincinnati Children's licenses the technology to the personal medicine company AssureX.
Tsuyoshi Fukuda, PhD
Tsuyoshi Fukuda, PhD was awarded a CCTST T1 Pilot Collaborative Studies (PCS) Grant for his application entitled "Novel PK/PG Approach for Morphine Treatment in Neonates". Inadequate pain control in neonates is an important clinical concern with potential long adverse consequences. By studying the pharmacokinetics and pharmacogenetics of morphine in neonates we will gain insight in the factors that cause some patient to respond well whereas others have inadequate pain control or adverse drug reactions.
Chie Emoto, PhDChie Emoto, PhD was awarded with a Goldstein Trainee Award as well as with President’s Award during the 2014 Annual Meeting of the American Society of Clinical Pharmacology and Therapeutics.