Tail Suspension
Tail Suspension: This test measures immobility in mice (not used in adult rats) by suspending the animal from an acrylic plate by the tail. Mice quickly determine that there is no escape and eventually stop struggling. Antidepressants increase struggling and sedatives decrease struggling. The test overlaps with what is measured in the FST but provides converging evidence when the two tests show similar results. Our procedure suspends animals for a single trial of 6 min duration and time spent immobile is recorded by the experimenter manually
