Cardiovascular Imaging Core Research Laboratory

Thomas R. Kimball, MD

Title

Director, Echocardiography

Appointment

Professor of Pediatrics

Email

tom.kimball@cchmc.org

Phone

513-636-8270

Fax

513-636-3952

Bio

Thomas R. Kimball, MD, is currently the director of Echocardiography and the director of the Cardiovascular Imaging Core Research Laboratory at Cincinnati Children's Hospital Medical Center.

A native of California, Dr. Kimball graduated with Distinction and Honors from Stanford University. He earned his medical degree from New York University, New York, NY.

Dr. Kimball completed his pediatric internship and residency at Children's Hospital of Los Angeles and his pediatric cardiology fellowship at Cincinnati Children's Hospital Medical Center.

Dr. Kimball has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1988. He became director of Echocardiography in 1998.

Dr. Kimball's academic interests relate to echocardiography and he has made numerous scholarly contributions in the field of ventricular function utilizing echocardiography, particularly in the field of hypertension and obesity.

Dr. Kimball has established collaborative relationships with basic scientists at the University of Cincinnati College of Medicine using echocardiography to evaluate phenotypes of transgenic mice, including embryonic mice.

Dr. Kimball has been active in the cardiology community. He is a member of the American Society of Echocardiography, American Heart Association, American Academy of Pediatrics, American College of Cardiology and an investigator in the NIH Pediatric Heart Network.

Dr. Kimball was also a member of the first Family Advisory Council at Cincinnati Children's and received the 2006 Family Advisory Council Award of Excellence.

Credentials

BS: Stanford University with Honors and Distinction, Stanford, CA, 1978.

MD: New York University School of Medicine, New York City, NY, 1982.

Residency: Pediatrics, Children's Hospital of Los Angeles, Los Angeles, CA, 1985.

Fellowship: Pediatric Cardiology, Children's Hospital Medical Center, Cincinnati, OH, 1988.

Certification: Pediatrics, 1986; Pediatric Cardiology, 1991 (recertification, 1997, 2004).

Awards and Honors

Nominee, American Society of Echocardiography Richard Popp Award – for contribution to education in echocardiography, 2004, 2005.
Nominee, American Society of Echocardiography Excellence-In-Teaching Award, 2006.
Family Advisory Council Award of Excellence in Family Centered Care, Cincinnati Children's Hospital Medical Center, 2006.
Best Doctors in America, 2008

Research

Ventricular function
Transgenic mice phenotyping
Cardiovascular changes with obstructive sleep apnea
Cardiovascular changes with renal disease
Pediatric obesity
Cardiovascular changes in fit and unfit children
Echocardiography quality assurance

Research Grants and Contracts

2001 - 2007: Principal Investigator, "Visceral Adiposity and CVD Risk in Women". National Institute of Health.

2002 - 2007: Mentor, "Cardiac Disease in Children with Chronic Renal Failure". National Institute of Health.

2003 - 2008: Co-Investigator, "Mechanisms Mediating Cardiac and Vascular Disease in Children with Obstructive Sleep Apnea". National Institute of Health.

2004 - 2007: Co-Investigator, "Wright State subcontract Longitudinal Cardiac Outcomes and Body Composition". National Institute of Health.

2004 - 2008: Co-Investigator, "SCCOR in Pediatric Heart Development and Disease Core B: Echocardiographic Studies of Valvular Heart Disease". National Institute of Health.

2005 - 2009: Principal Investigator, "CV Disease in Adolescents with Type 2 Diabetes". National Institute of Health.

Publications, Most Recent

de Simone, G.; Daniels, S.R.; Kimball, T.R.; Roman, M.J.; Romano, C.; Chinali, M.; Galderisi, M.; Devereux, R.B.: Evaluation of concentric left ventricular geometry in humans-evidence for age-related systematic underestimation.Hypertension, January 2005; 64-68.

Ayres, N.A.; Miller-Hance, W.; Fyfe, D.A.; Stevenson, J.G.; Sahn, D.J.; Young, L.T.; Minich, L.L.; Kimball, T.R.; Geva, T.; Smith, F.C.; Rychik, J.: American Society of Echocardiography Report. Indications and guidelines for performance of transesophageal echocardiography in the patient with pediatric acquired or congenital heart disease.J Am Soc Echocardiogr, January 2005; 18(1):91-8.

Kalra, M.; Kimball, T.R.; Daniels, S.R.; LeMasters, G.; Willging, P.J.; Rutter, M.; Witt, S.A.; Glascock, B.J.; Amin, R.S.: Structural cardiac changes as a predictor of respiratory complications after adenotonsillectomy for obstructive breathing during sleep in children.Sleep Medicine 6, 2005; 241-245.

Amin, R.S.; Kimball, T.R.; Kalra, M.; Jeffries, J.L.; Carroll, J.L.; Bean, J.A.; Witt, S.A.; Glascock, B.J.; Daniels, S.R.: Left ventricular function in children with sleep-disordered breathing.Am J Cardiol, March 15, 2005; 95(6):801-4.

Mitsnefes, M.M.; Kimball, T.R.; Kartal, J.; Witt, S.A.; Glascock, B.J.; Khoury, P.R.; Daniels, S.R.: Cardiac and vascular adaptation in pediatric patients with chronic kidney disease: role of calcium-phosphorus metabolism.J Am Soc Nephrol, September 2005; 16(9):2796-803.

Sanders, S.P.; Colan, S.D.; Cordes, T.M.; Donofrio, M.T.; Ensing, G.J.; Geva, T.; Kimball, T.R.; Sahn, D.J.; Silverman, N.H.; Sklansky, M.S.; Weinberg, P.M.: ACCF / AHA / AAP recommendations for training in pediatric cardiology. Task force 2: pediatric training guidelines for noninvasive cardiac imaging endorsed by the American Society of Echocardiography and the Society of Pediatric Echocardiography.J Am Coll Cardiol, October 4, 2005; 46(7):1384-8.

Allen, H.D.; Bricker, J.T.; Freed, M.D.; Hurwitz, R.A.; McQuinn, T.C.; Schieken, R.M.; Strong, W.B.; Zahka, K.G.; Sanders, S.P.; Colan, S.D.; Cordes, T.M.; Donofrio, M.T.; Ensing, G.J.; Geva, T.; Kimball, T.R.; Sahn, D.J.; Silverman, N.H.; Sklansky, M.S.; Weinberg, P.M.; Beekman, R.H. 3rd; Hellenbrand, W.E.; Lloyd, T.R.; Lock, J.E.; Mullins, C.E.; Rome, J.J.; Teitel, D.F.; Vetter, V.L.; Silka, M.J.; VanHare, G.F.; Walsh, E.P.; Kulik, T.; Giglia, T.M.; Kocis, K.C.; Mahoney, L.T.; Schwartz, S.M.; Wernovsky, G.; Wessel, D.L.; Murphy, D.J. Jr.; Foster, E.; Benson, D.W. Jr; Baldwin, H.S.; Mahoney, L.T.; McQuinn, T.C.: ACC / AHA / AAP recommendations for training in pediatric cardiology.Pediatrics, December 2005; 116(6):1574-96.

Graham, T.P. Jr,; Beekman, R.H. 3rd; Allen, H.D.; Bricker, J.T.; Freed, M.D.; Hurwitz, R.A.; McQuinn, T.C.; Schieken, R.M.; Strong, W.B.; Zahka, K.G.; Sanders, S.P.; Colan, S.D.; Cordes, T.M.; Donofrio, M.T.; Ensing, G.J.; Geva, T.; Kimball, T.R.; Sahn, D.J.; Silverman, N.H.; Sklansky, M.S.; Weinberg, P.M.; Hellenbrand, W.E.; Lloyd, T.R.; Lock, J.E.; Mullins, C.E.; Romes, J.J.; Teitel, D.F.; Vetter, V.L.; Silka, M.J.; VanHare, G.F.; Walsh, E.P.; Kulik, T.; Giglia, T.M.; Kocis, K.C.; Mahoney, L.T.; Schwartz, S.M.; Wernovsky, G.; Wessel, D.L.; Murphy, D. Jr; Foster, E.; Benson, D.W. Jr; Baldwin, H.S.; Hirshfeld, J.W. Jr; Kugler, J.D.; Moskowitz, W.B.; Creager, M.A.; Lorell, B.H.; Merli, G.; Rodgers, G.P.; Rutherford, J.D.; Tracy, C.M.; Weitz, H.H.: ACCF / AHA / AAP recommendations for training in pediatric cardiology. A report of the American College of Cardiology Foundation / American Heart Association / American College of Physicians Task Force on Clinical Competence (ACC/AHA/AAP Writing Committee to develop training recommendations for pediatric cardiology), October 18, 2005; 112(16):2555-80.

Xu, J.; Kimball, T.R.; Lorenz, J.N.; Brown, D.A.; Bauskin, A.R.; Klevitsky, R.; Hewett, T.E.; Breit, S.N.; Molkentin, J.D.: GDF15 / MIC-1 Functions as a protective and antihypertrophic factor released From the myocardium in association with SMAD protein activation.Circ Res, 2006; 98(3):342-50.

Paridon, S.M.; Alpert, B.S.; Boas, S.R.; Cabrera, M.E.; Caldarera, L.L.; Daniels, S.R.; Kimball, T.R.; Knilans, T.K.; Nixon, P.A.; Rhodes, J.; Yetman, A.T.: Clinical Stress testing in the pediatric age group: a statement from the American Heart Association Council on Cardiovascular Disease in the Young, Committee on Atherosclerosis, Hypertension, and Obesity in Youth.Circulation, April 18, 2006; 113(15):1905-20.

Sanna, B.; Brandt, E.B.; Kaiser, R.A.; Pfluger, P.; Witt, S.A.; Kimball, T.R.; van Rooij, E.; DeWindt, L.J.; Rothenberg, M.E.; Tschop, M.H.; Benoit, S.C.; Molkentin, J.D.: Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.Proceedings of the National Academy of Sciences, May 9, 2006; 103(19):7327-32.

Hambleton, M.; Hahn, H.; Pleger, S.T.; Kuhn, M.C.; Klevitsky, R.; Carr, A.N.; Kimball, T.R.; Hewett, T.E.; Dorn II, G.W.; Koch, W.J.; Molkentin, J.D.: Pharmacological- and Gene Therapy-Based Inhibition of Protein Kinase Cα/β Enhances Cardiac Contractility and Attenuates Heart Failure.Circulation, July 2006; 10.1161/circulation NAHa.105.592550.

Presentations, Most Recent

Kudchadker, N.; Goya, G.; Mays, W.; Lee, L.; Glascock, B.J.; Witt, S.A.; Kimball, T.R.: Can we predict left ventricular outflow tract obstruction in pediatric patients with hypertrophic cardiomyopathy? Presented at the American Academy of Pediatrics National Conference and Exposition; October 9, 2004; San Francisco, CA.

Ippisch, H.M.; Witt, S.; Glascock, B.; Inge, T.; Garcia, V.; Daniels, S.R.; Kimball, T.R.: Does gastric bypass surgery decrease cardiac risk factors in morbidly obese young patients? Presented at the American Academy of Pediatrics 2004 National Conference and Exhibition; October 9, 2004; San Francisco, CA.

Ippisch, H.M.; Witt, S.; Glascock, B.; Inge, T.; Garcia, V.; Daniels, S.R.; Kimball, T.R.: Does gastric bypass surgery decrease cardiac risk factors in morbidly obese young patients? Presented at the 77th Scientific Sessions of the American Heart Association; November 7, 2004; New Orleans, LA.

Witt, S.A.; Glascock, B.J.; Kimball, T.R.: High resolution in vivo micro imaging echocardiography provides enhanced cardiac detailing in mice. Presented at the 77th Scientific Sessions of the American Heart Association; November 7, 2004; New Orleans, LA.

de Simone, G.; Daniels, S.R.; Kimball, T.R.; Roman, M.J.; Galderisi, M.; de Divitiis, O.; Devereux, R.B.: Evaluation of concentric left ventricular geometry in humans: evidence for age-related systematic underestimation. Presented at the 54th Scientific Sessions of the American College of Cardiology; March 8, 2005; Orlando, FL.

Reynolds, K.A.; Kimball, T.R.; Khoury, P.R.: Cardiac ventricular interaction: effect of right ventricular overload on left ventricular hemodynamics. Presented at the National Student Research Foundation; April 29, 2005; Galveston, TX.

Hao, M.; Ippisch, H.M.; Cook, R.S.; Perry, D.L. Gottliebson, W.M.; Hirsch, R.; Kimball, T.R.: Implementation of an objective testing system in noninvasive cardiac imaging for pediatric cardiology fellows. Presented at Ohio Doctors Interested in Congenital Heart Disease Annual Conference; May 13, 2005; Dayton, OH.

Border, W.L.; Swingler, G.H.; Kimball, T.R.: The discriminatory ability of Doppler echocardiography to assess clinically significant heart disease in children. Presented at the 16th Annual Scientific Sessions of the American Society of Echocardiography; June 17, 2005;Boston, MA.

Wisler, J.; Kimball, T.R.: The effect of left ventricular size on right ventricular hemodynamics in children with hypoplastic left heart syndrome. Presented at the National Student Research Foundation; April 2006; Galveston, TX.