Long (Jason) Lu, PhD
Title
Assistant Professor
Appointment
Assistant Professor of Pediatrics
Email
long.lu@cchmc.org
Phone
513-636-8720
Fax
513-636-2056
Credentials
Postdoctoral Research Associate in Bioinformatics: Yale University, New Haven, CT, 2003-06.
PhD: Biochemistry, specialized in Computational Molecular Biology, Washington University School of Medicine, St. Louis, MO, 2003.
BS: Biotechnology/Bioengineering, Peking University, Beijing, China, 1998.
Research Grants and Contracts
Title: Breast Cancer Biomarker Discovery Using Protein Network
Sponsor: American Cancer Society
Dates: 01/01/2008 - 12/31/2008
Publications, Most Recent
He F, Wen Y, Deng J, Lin X, Lu LJ, Jiao R, et al. Probing intrinsic properties of a robust morphogen gradient in Drosophila. Dev Cell. 2008 Oct;15(4):558-67.
Zha DJ, Wang ZM, Lin Y, Liu T, Qiao L, Lu LJ, et al. Effects of noradrenaline on the GABA response in rat isolated spiral ganglion neurons in culture. J Neurochem. 2007 Oct;103(1):57-66.
Huang YJ, Hang D, Lu LJ, Tong L, Gerstein MB, Montelione GT. Targeting the human cancer pathway protein interaction network by structural genomics. Mol Cell Proteomics. 2008 Oct;7(10):2048-60.
Lu LJ, Nishino TK, Khamapirad T, Grady JJ, Leonard MH, Jr., Brunder DG. Computing mammographic density from a multiple regression model constructed with image-acquisition parameters from a full-field digital mammographic unit. Phys Med Biol. 2007 Aug 21;52(16):4905-21.
Wu L, Hwang SI, Rezaul K, Lu LJ, Mayya V, Gerstein M, et al. Global survey of human T leukemic cells by integrating proteomics and transcriptomics profiling. Mol Cell Proteomics. 2007 Aug;6(8):1343-53.
Liu YL, Nie ZY, Lu LJ, Hui YZ. [Peritoneal "melanosis": report of a case]. Zhonghua Bing Li Xue Za Zhi. 2007 Aug;36(8):572-3.
Lu LJ, Sboner A, Huang YJ, Lu HX, Gianoulis TA, Yip KY, et al. Comparing classical pathways and modern networks: towards the development of an edge ontology. Trends Biochem Sci. 2007 Jul;32(7):320-31.
Flores SC, Lu LJ, Yang J, Carriero N, Gerstein MB. Hinge Atlas: relating protein sequence to sites of structural flexibility. BMC Bioinformatics. 2007;8:167.
Kim PM, Lu LJ, Xia Y, Gerstein MB. Relating three-dimensional structures to protein networks provides evolutionary insights. Science. 2006 Dec 22;314(5807):1938-41.
Xia Y, Lu LJ, Gerstein M. Integrated prediction of the helical membrane protein interactome in yeast. J Mol Biol. 2006 Mar 17;357(1):339-49.
Flores S, Echols N, Milburn D, Hespenheide B, Keating K, Lu J, et al. The Database of Macromolecular Motions: new features added at the decade mark. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D296-301.
Lu LJ, Xia Y, Paccanaro A, Yu H, Gerstein M. Assessing the limits of genomic data integration for predicting protein networks. Genome Res. 2005 Jul;15(7):945-53.
Lu L, Xia Y, Yu H, Rives A, Lu H, Schubert F, et al. Protein interaction prediction by integrating genomic features and protein interaction network analysis. In: Azuaje F, Dopazo J, editors. Data Analysis and Visualization in Genomics and Proteomics. Hoboken: Wiley; 2005. p. 61-81.
Lu L, Arakaki AK, Lu H, Skolnick J. Multimeric threading-based prediction of protein-protein interactions on a genomic scale: application to the Saccharomyces cerevisiae proteome. Genome Res. 2003 Jun;13(6A):1146-54.
Lu H, Lu L, Skolnick J. Development of unified statistical potentials describing protein-protein interactions. Biophys J. 2003 Mar;84(3):1895-901.
Lu L, Lu H, Skolnick J. MULTIPROSPECTOR: an algorithm for the prediction of protein-protein interactions by multimeric threading. Proteins. 2002 Nov 15;49(3):350-64.
More Information
For more information, visit the Lu Lab web site: http://dragon.cchmc.org.
