Funded grants with Principal Investigators from the Imaging Research Center
Pediatric Study Centers for a MRI study of Normal Brain Development
Principal Investigator: William S. Ball, Jr. M.D.
Agency: NIH NINDS
The major goal is to acquire data in support of a NIH database of normal anatomical images of children from ages 5 to 18 years.
MR Assessment of Brain Function Altered by Lead Exposure
Principal Investigator: Kim M. Cecil, Ph.D.
Agency: NIH NIEHS/EPA
This project specifically examines young adults with a childhood history of lead exposure with advanced neuroimaging techniques to evaluate structure, metabolism and behavior. It is one of five projects as part of the Children's Environmental Health Center Study of Prevalent Neurotoxicants in Children.
Imaging Water Mobility of Cartilage in Juvenile Rheumatoid Arthritis
Principal Investigator: Bernard J. Dardzinski, Ph.D.
Agency: The Arthritis Foundation
The goal of this project is to investigate the measurement of 1H T2 relaxation as a means to assess alteration in articular cartilage water mobility in the knee joint of patients with JRA.
Cincinnati Rheumatic Disease Center: Imaging Research Core
Principal Investigator: Bernard J. Dardzinski, Ph.D.
Agency: NIH
This core center is to provide technical expertise, assistance and equipment to those investigators who require noninvasive methods to monitor disease progression in rheumatoid arthritis and animal models of autoimmune diseases.
Quantitative MRI of Cartilage and Synovium in JRA
Principal Investigator: Bernard J. Dardzinski, Ph.D.
Agency: NIH NIAMS
The goal of this project is to investigate magnetic resonance (MR) imaging as an outcome assessment tool to monitor whether changes in MR imaging parameters are predictive of future articular cartilage erosions in children with juvenile rheumatoid arthritis (JRA). It is a project within the NIAMS Multidisciplinary Clinical Research Center in Cincinnati.
MRI T2 Mapping of Cartilage for Diagnosis of Early OA
Principal Investigator: Bernard J. Dardzinski, Ph.D.
Agency: NIH NIAMS
The goal of this project is to develop and validate a reproducible, quantitative, imaging technique that is sensitive to structural changes in the extracellular matrix that precede the loss of articular cartilage. This is a consortium agreement with PENN State University, Hershey Medical Center.
FMRI of Normal Language Development in Children
Principal Investigator: Scott K. Holland, Ph.D.
Agency: NIH
This project uses functional MRI to map normal cortical activation patterns associated with language functions throughout development in children ages 5-18.
FMRI of Pediatric Cochlear Implant Candidates
Principal Investigator: Scott K. Holland, Ph.D.
Agency: NIH
This project is A feasibility study to determine whether functional MRI of auditory stimulation in deaf toddlers and children with and without sedation might be useful as an evaluation tool for selecting candidates for cochlear implantation.
Please visit our website
www.irc.cchmc.org for collaborative grants with PI's outside of the IRC.
