Magnetic Resonance Imaging (MRI) study to track the progress of juvenile rheumatoid arthritis (JRA) sponsored by the National Institute of Health.
What is the purpose of this study?
The purpose of this study is to determine if using Magnetic Resonance Imaging (MRI) allows doctors to track the progression of juvenile rheumatoid arthritis and evaluate therapy.
Who will be included?
Healthy children and children who have been diagnosed with juvenile rheumatoid arthritis ages 5 to 18 years old will be included in this study. The JRA participants must have symptoms for at least 6 months. Participants cannot have any type of metal implants and must not have a fear of being in small places.
What is Involved?
This study involves 4-5 outpatient visits during a five-year time period. Parents interested in having their child participate will be given a consent form that thoroughly explains the details of the study for them to sign and for the participants to give their approval. After the consent form is completed at the first visit, parents and the participant will be asked some questions about the participant's medical history and about any medications they are currently taking.
At every visit participants will have an MRI done that will last approximately 45 minutes. During the MRI they may be able to watch a movie or listen to music. Parents will be asked to complete a questionnaire.
Children who have had JRA for less than two years will also have their blood drawn at every visit and an IV inserted so a contrast enhanced MRI can be completed.
What are the Benefits?
The most direct benefit of participating in a clinical trial is that your child is helping other children. Clinical studies are essential in finding new and improved treatments and diagnostic tools. However, your child may receive no direct benefit from participating in this study.
What are the Risks?
Some discomfort may occur due to noise produced by the MRI scanner. Headphones will be provided so that your child can listen to music and also to minimize the noise level. Subjects who have a fear of small places will not be included in the study. Other than these types of discomforts there are no known risks associated with MRI.
What is the compensation?
Participants will receive a $50 gift certificate.
Who should I contact for more information?
Contact the Imaging Research Center at 513-636-7230.
