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Adolescent Medicine

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Lorah D. Dorn

Title

Director of Research

Appointment

Professor, University of Cincinnati College of Medicine

Email

lorah.dorn@cchmc.org

Phone

513-636-7204

Bio

Dr. Dorn is the Director of Research in the Division of Adolescent Medicine.  In this capacity she oversees research within the division. She mentors young researchers, often helping them to find funding, and encourages collaborations with other departments, sometimes introducing researchers with similar interest.  Additionally she provides consultation on grant writing, scientific issues related to research methodology, IRB submissions, and manuscript writing.  Within Children’s Hospital she serves on various committees related to conducting and funding clinical research.  Her own research focuses on biobehavioral issues during puberty and their impact on health and development.  Specific studies focus on the outcomes of mental health variables including psychopathology, as well as physical health variables including bone density.

Credentials

Ph.D: The Pennsylvania State University, 1989

Post doctoral Fellowship: Clinical Neuroendocrinology, NIH/NIMH, 1993

Masters: Catholic University of America, 1983

Certification: Pediatric Nurse Practitioner

Position History

Dr. Dorn joined the Division of Adolescent Medicine as a Professor and Director of Research in 2003.


Awards and Honors

2006 Ninth Annual Doctor Elliott Podoll Adolescent Medicine Lectureship, University of Louisville
 
2001 Research Award, Eta Chapter of Sigma Theta Tau
 
2000-2004 Junior Faculty Scholar Robert  Wood Johnson, Tobacco Etiology Research Network

1994-1995 Ruth Perkins Kuehn Research  Award, University of Pittsburgh, School of Nursing
 
1983-present Fellow, National Association for Pediatric Nurse Associates and Practitioners (NAPNAP)
 
1981-1982 Kappa Alpha Theta National Graduate Scholarship

Research

Adolescent anxiety, depression and smoking;  pubertal timing and premature adrenarche;  behavior and behavior problems; endocrine development and changes, behavioral endocrinology.

Research Grants and Contracts

Current Principal Investigator
Source: NIDA; Title: Smoking and Metabolic Consequences in Adolescent Girls; Principal Investigator: Lorah Dorn; Percent Time: 30%; Period of Support: 2/1/04-1/31/09; Annual Direct Costs: $310,003.
 
Source: NINR: Title: Endocrine Changes and Treatment of Conduct Problems; Principal Investigator: Lorah Dorn; Percent Time: 30%; Period of Support: 09/01/03-08/31/08; Annual Direct Costs: $296,370.
 
Current Co-Investigator
Source:  NIH-UC Subcontract (U01 ES12770-01); Title: Puberty and Cancer Initiation:  Environment, Diet, and Obesity; Principal Investigator:  Heffelfinger (Dr. Frank Biro serves as the Principal Investigator for the human (epidemiologic) studies for the Cincinnati site); Percent time: L.D. Dorn, 5%, Period of Support: 09/01/03 – 08/31/10; Annual Direct Costs: $272,490
 
Source:  NIH/NIDA 1R01DA019965-01A1; Title: Innovative Modeling of Puberty and Substance Use Risk: Principal Investigator: Huang: Percent time: L.D. Dorn, 16%, Period of Support: 04/10/06 - 12/31/09, Annual Direct Costs:$153,913

 

Publications, Most Recent

  • Dorn, L.D., Susman, E.J., Pabst, S.R., Huang, B., Kalkwarf, H.J., & Grimes, S. (2008). The association of depressive symptoms and anxiety with bone mass and density in ever smoking and never smoking adolescent girls.  Archives of Pediatrics and Adolescent Medicine, 162(12),1181-1188. This paper found that high depressive symptoms and anxiety were associated with lower bone mineral density and content. Smokers had higher depression and anxiety than nonsmokers. Subgroup analyses suggested that in smokers higher anxiety was related to lower bone mineral content.

  • Dorn, L.D., Negriff, S., Huang, B., Pabst, S., Hillman., J., Braverman, P., & Susman, E.J. (2009). Menstrual Symptoms in Adolescent Girls:  Association with Smoking, Depressive Symptoms and Anxiety.  Journal of Adolescent Health, 44, 237-243. This paper found that high depressive symptoms and anxiety were related to more menstrual symptoms. Smokers had more menstrual symptoms than nonsmokers and the association between depressive symptoms/anxiety and menstrual symptoms was stronger for smokers.

  • Pabst, S.R., Negriff, S., Huang, B., Susman. E.J., & Dorn, L.D. (in press). Depression and anxiety in adolescent females: The impact of sleep preference and body mass index.Journal of Adolescent Health.This paper found that evening chronotype (having an evening sleep preference, e.g. going to bed later) was related to higher depressive symptoms and anxiety. This effect was stronger in overweight girls. The combination of evening chronotype and being overweight appears to have the strongest association on the emotional health of adolescent females.

  • Marklein, E., Negriff, S., & Dorn, L.D. (in press). Pubertal timing, substance use, and peer smoking.Prevention Science. This paper found that late pubertal timing was associated with more alcohol use. Also having more friends that were regular smokers was related to the girl’s use of cigarettes, alcohol, and marijuana. Having friends that smoke strongly influences an adolescent’s use of substances.

  • Negriff, S. & Dorn, L.D. (in press). Morningness-Eveningness and menstrual symptoms in adolescent girls.Journal of Psychosomatic Research. This paper found that evening chronotype (having an evening sleep preference, e.g. going to bed late) was associated with more menstrual symptoms and shorter duration of menses. Girls with evening sleep preference experience more menstrual symptoms than girls with morning preference.

  • Dorn, L.D., Susman, E.J., Pabst, S., Huang, B., Kalkwarf, H., Grimes, S. The Association of Depressive Symptoms and Anxiety with Bone Health in Ever Smoking and Never Smoking Adolescent Girls.  Archives of Pediatric and Adolescent Medicine (in press).

  • Dorn, L.D., (2008). Adolescent Participation in Research.  In G.S. Slap (ed), Adolescent Medicine: The Requisites in Pediatrics.  Philadelphia: Mosby, Inc.

  • Kolko, D.J., Dorn, L.D., Bukstein, O., Burke, J.D. (2008) Clinically referred ODD Children with or without CD and Healthy Controls:  Comparisons across contextual domains. Journal of Child and Family Studies, 17(5): 714-734.

  • Dorn, L.D., Rose, S.R., Rotenstein, D, Susman, E.J., Huang, B., Loucks, T.L., Berga, S.L. (2008) Differences in Endocrine Parameters and Psychopathology in Girls with Premature Adrenarche versus On-time Adrenarche.   Journal of Pediatric Endocrinology & Metabolism, 21(5) 439-448.

  • Matchock, R.L., Dorn, L.D., Susman, E.J. (2007).  Diurnal and Seasonal Cortisol, Testosterone, and DHEA Rhythms in Boys and Girls During Puberty.   Chronobiology International, 24(5):969-990.

  • Susman, E.J., Dockray, S., Schiefelbein, V.L., Herwehe, S., Heaton, J.A., & Dorn, L.D. (2007). Morningness/Eveningness, Morning to Afternoon Cortisol Ratio and Antisocial Behavior Problems During Puberty.   Developmental Psychology. 43(4):811-822.

  • Dorn, L.D., Lucke, J.F., Berga, S.L., Loucks, T.L. (2007). Salivary Cortisol Reflects Serum Corticol:  Analysis of Circadian Profiles.   Annals of Clinical Biochemistry. 44:281-284.

  • Dorn, L.D. (2007).  Psychological Abnormalities Associated with Premature Adrenarche and Precocious Puberty.  In O. Pescovitz & E. Walvoord (Eds.), When Puberty is Precocious:  Scientific and Clinical Aspects (pp. 309-327). Totowa, NJ: The Humana Press.

  • Susman, E.J., Dockray, S., Schiefelbein, V.L., Herwehe, S., Heaton, J.A. & Dorn, L.D.  (2007) Morningness/ Eveningness, Morning to Afternoon cortisol Ratio and Antisocial Behavior Problems During Puberty.   Developmental Psychology, 43(4):811-22.

    Dorn, L.D. (2006) Measuring puberty.  Journal of Adolescent Health.  39(5): 625-626.

  • Dorn, L.D., Dahl, R.E., Woodward, H.R., Biro, F.M.  (2006) Defining the Boundaries of Early Adolescence:  A User’s Guide to Assessing Pubertal Status and Pubertal Timing in Research with Adolescents.Applied Developmental Science. 10 (1):30-56.


Presentations, Most Recent

Pabst, S.R., Dorn, L.D., Negriff, S. Effect of Morning-Evening Preference and Body Mass Index on Depressive Symptoms and Anxiety in Adolescent Females.  Poster presented at Society for Research on Adolescence, Chicago, IL. March 2008

Kowalczyk Mullins, T., Braverman, P.K., Dorn, L.D., Kollar, L.M. (March 10, 2008). Preference for HIV Testing Methods and Factors Associated with Choice of an HIV Test Among Urban Adolescents.  Presented at the 2008 National STD Prevention Conference in Chicago, IL.

Dorn, L.D. (March 17, 2008).  2nd National Congress of the Hellenic Pediatrician’s College, Athens, Greece.  Smoking, depression and bone health in adolescent girls in the Symposium was Child and AdolescentDevelopment and Behavior.

Dorn, L.D. (August 22, 2007).  Puberty in the 21st Century. 13th European Conference on Developmental Psychology, University of Jena, Jena, Germany.

Dorn, L.D. (August 21, 2007).  One fits all? – Appropriate Measurements of Pubertal Status and Timing According to Research Question and Study Design. Workshop entitled “Methods for Assessing Pubertal Status and Pubertal Timing within Developmental Science”, 13th European Conference on Developmental Psychology, University of Jena, Jena, Germany.

Dorn, L.D. (August 21, 2007).  Assessing Pubertal Status and Pubertal Timing:  Focus on Biological Measures.  Workshop entitled “Methods for Assessing Pubertal Status and Pubertal Timing within Developmental Science”, 13th European Conference on Developmental Psychology, University of Jena, Jena, Germany.

Dorn, L.D. (February 16, 2006). Biological Transitions as a Period of Vulnerability: Puberty and the Stress System.  Faculty Research Crosstalk.  Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Susman, E.J., Granger, D.A., Dockray, S., Heaton, J.A., Dorn, L.D. (March 24, 2006). Alpha-amylase, timing of puberty and disruptive behavior in young adolescents:  A test of the attenuation hypothesis.  Paper presentation in symposium entitled, “Physiological reactivity, behavior, cognition and health:  A new approach involving salivary alpha-amylase and cortisol”, Chair. D.A. Granger at the Society for Research on Adolescence biennial meeting, San Francisco, CA.

Professional Organization Memberships

2005 American Pediatric Society (elected member)
 
2004 Academy of Behavioral Medicine Research (elected member)
 
2003 Society for Adolescent Medicine
 
1996-present Society for Research on Child Development (SRCD)
 
1986-present Society for Research on Adolescence (SRA)Co-chair,
ProgramCommittee, Biennial Meeting (2006)
Chair, Membership
Committee (2006-present)
Chair, Psychobiological and Health Review Committee (2007)
 
1983-present Fellow National Association for Pediatric Nurse Associates and Practitioners (NAPNAP)
 
1977-present Sigma Theta Tau Nursing Honorary Scholarship Chair, Eta Chapter (1994-1995) Leadership Committee Member, Eta Chapter (1997-1998)                                                               

Grant Reviewer  

  • Ad Hoc reviewer for Scientific proposals at Western Psychiatric Institute and Clinics (1995- 2003).
  • Reviewer, National Institutes of Health, Center for Scientific Review Special Emphasis Panel (ZRG1 F12B-G 20), Psychopathology, Developmental Disabilities, Stress and Aging (July 6-7, 2006).

 
Editorial Board

  • Journal of Research on Adolescence, September 1996 to 2000


 
Book/Journal Reviewer

  • Ad Hoc reviewer for various journals including, Journal of Adolescent Health, Journal of Early Adolescence, Biological Psychiatry, Journal of Clinical Endocrinology and Metabolism, Psychoneuroendocrinology, and Psychosomatic Medicine.