Division of Allergy and Immunology
Current Publications
2009
Vicario M, Blanchard C, Stringer KF, Collins MH, Mingler MK, Ahrens A, et al. Local B cells and IgE production in the esophageal mucosa in Eosinophilic Esophagitis. Gut 2009.
Rothenberg ME. Biology and Treatment of Eosinophilic Esophagitis. Gastroenterology 2009.
Rothenberg ME. Molecular diagnostics and treatment of patients with the hypereosinophilic syndrome. Clin Adv Hematol Oncol 2009; 7:43-4.
Niese KA, Collier AR, Hajek AR, Cederbaum SD, O'Brien WE, Wills-Karp M, et al. Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunol. 2009; 10:33.
Yamada Y, Cancelas JA, Rothenberg ME. Murine model of hypereosinophilic syndromes/chronic eosinophilic leukemia.
Int Arch Allergy Immunol. 2009; 149 Suppl 1:102-7.
Putnam PE, Rothenberg ME. Eosinophilic esophagitis: concepts, controversies, and evidence. Curr Gastroenterol Rep. 2009; 11:220-5.
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, et al. CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature. 2009.
Lu TX, Munitz A and Rothenberg ME. MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J Immunol. 2009 Apr 15;182(8):4994-5002.
Munitz A, Seidu L, Cole ET, Ahrens R, Hogan SP and Rothenberg ME. Resistin-like molecule alpha decreases glucose tolerance during intestinal inflammation. J Immunol. 2009 Feb 15;182(4):2357-63.
Blanchard C, Rothenberg, ME. Chemotactic Factors Associated with Eosinophilic Gastrointestinal Diseases. In: Furuta, GT, Atkins, D, Alam, R (eds): Immunology and Allergy Clinics of North America . Volume 29(1); pp 141-148. Philadelphia: WB Saunders, 2009.
Miyazaki D, Nakamura T, Ohbayashi M, Kuo CH, Komatsu N, Yakura K, Tominaga T, Inoue Y, Higashi H, Murata M, Takeda S, Fukushima A, Liu FT, Rothenberg ME and Ono SJ. Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade. Int Immunol. 2009 Feb;21(2):187-201.
Pentiuk S, Putnam PE, Collins MH, Rothenberg ME. Dissociation between symptoms and histological severity in pediatric eosinophilic esophagitis. J Pediatr Gastroenterol Nutr, 2009 Feb;48(2):152-60.
Blanchard C, Rothenberg ME. Chapter 3 biology of the eosinophil. Adv Immunol, 2009;101:81-121.
Brandt EB, Munitz A, Orekov T, Mingler MK, McBride M, Finkelman FD, Rothenberg ME. Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea. J Allergy Clin Immunol, 2009 Jan;123(1):53-8.
2008
DeBrosse CW, Rothenberg ME. Allergy and eosinophil-associated gastrointestinal disorders (EGID). Curr Opin Immunol, 2008 Dec;20(6):703-8.
Munitz A, Waddell A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME. Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis. J Allergy Clin Immunol, 2008 Dec;122(6):1200-1207.e1.
Ahrens R, Waddell A, Seidu L, Blanchard C, Carey R, Forbes E, Lampinen M, Wilson T, Cohen E, Stringer K, Ballard E, Munitz A, Xu H, Lee N, Lee JJ, Rothenberg ME, Denson L, Hogan SP.Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis. J Immunol, 2008 Nov 15;181(10):7390-9.
Rothenberg ME, Stein M. Reply. J Allergy Clin Immunol, 2008 Oct 23.
Collins MH, Putnam PE, Rothenberg ME. Reply. Clin Gastroenterol Hepatol, 2008 Oct 15.
Nizet V, Rothenberg ME. Mitochondrial missile defense. Nat Med, 2008 Sep;14(9):910-2.
Debrosse C.W.; Rothenberg M.E.: Allergy and eosinophil-associated gastrointestinal disorders (EGID). Curr Opin Immunol, 2008 Aug 19. [Epub ahead of print]
Zimmermann N.; McBride M.L.; Yamada Y.; Hudson S.A.; Jones C.; Cromie K.D.; Crocker P.R.; Rothenberg M.E.; Bochner B.S.: Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils. Allergy, 2008 Sep; 63:1156-63.
Yamada Y.; Sanchez-Aguilera A.; Brandt E.B.; McBride M.; Al-Moamen N.J.; Finkelman F.D.; Williams D.A.; Cancelas J.A.; Rothenberg M.E.: FIP1L1/PDGFR{alpha} synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. Blood, 2008 Jun 6.
Johnson T.R.; Rothenberg M.E.; Graham B.S.: Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein. J Leukoc Biol, 2008 Sep;84:748-59.
Fulkerson P.C.; Rothenberg M.E.: Origin, regulation and physiological function of intestinal oeosinophils. Best Pract Res Clin Gastroenterol, 2008;22:411-23.
Stein M.L.; Villanueva J.M.; Buckmeier B.K.; Yamada Y.; Filipovich A.H.; Assa'ad A.H.; Rothenberg M.E.: Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels. J Allergy Clin Immunol, 2008 Jun;121:1473-83, 1483.e1-4.
Rothenberg M.E.; Klion A.D.; Roufosse F.E.; Kahn J.E.; Weller P.F.; Simon H.U.; Schwartz L.B.; Rosenwasser L.J.; Ring J.; Griffin E.F.; Haig A.E.; Frewer P.I.; Parkin J.M.; Gleich G.J.: Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N Engl J Med, 2008 Mar 20;358:1215-28.
Rothenberg M.E.: 2007 E. Mead Johnson Award: Scientific Pursuit of the Allergy Problem. Pediatr Res, 2008 Jul;64:110-5.
Munitz A.; McBride M.L.; Bernstein J. S.; Rothenberg M.E.: A dual activation and inhibition role for the paired immunoglobulin-like receptor B (PIR-B) in eosinophils. Blood, 2008 Jun 15;111:5694-703.
Munitz A.; Brandt E.B.; Mingler M.; Finkelman F.D.; Rothenberg M.E.: Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis. Proc Natl Acad Sci USA, 2008 May 20;105:7240-5.
Mishra A.; Wang M.; Pemmaraju V.R.; Collins M.H.; Fulkerson P.C.; Abonia J.P.; Blanchard C.; Putnam P.E.; Rothenberg M.E.: Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia. Gastroenterology, 2008 Jan;134:204-14.
Hogan S.P.; Rosenberg H.F.; Moqbel R.; Phipps S.; Foster P.S.; Lacy P.; Kay A.B.; Rothenberg M.E.: Eosinophils: biological properties and role in health and disease. Clin Exp Allergy, 2008 May;38:709-50.
Herbert D.R.; Orekov T.; Perkins C.; Rothenberg M.E.; Finkelman F.D.: IL-4R{alpha} Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis. J Immunol, 2008 Apr 1;180:4948-55.
Forbes E.E.; Groschwitz K.; Abonia J.P.; Brandt E.B.; Cohen E.; Blanchard C.; Ahrens R.; Seidu L.; McKenzie A.; Strait R.; Finkelman F.D.; Foster P.S.; Matthaei K.I.; Rothenberg M.E.; Hogan S.P.: IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med, 2008 Apr 14;205:897-913.
Collins M.H.; Blanchard C.; Abonia J.P.; Kirby C.; Akers R.; Wang N.; Putnam P.E.; Jameson S.C.; Assa'ad A.H.; Konikoff M.R.; Stringer K.F.; Rothenberg M.E.: Clinical, Pathologic, and Molecular Characterization of Familial Eosinophilic Esophagitis Compared With Sporadic Cases. Clin Gastroenterol Hepatol, 2008 Jun;6:621-9.
Brandt E.B.; Mingler M.K.; Stevenson M.D.; Wang N.; Khurana Hershey G.K.; Whitsett J.A.; Rothenberg M.E.: Surfactant protein D alters allergic lung responses in mice and human subjects. J Allergy Clin Immunol, 2008 May;121:1140-1147.e2.
Blanchard C.; Rothenberg M.E.: Basic pathogenesis of eosinophilic esophagitis. Gastrointest Endosc Clin N Am, 2008 Jan;18:133-43; x.
2007
Zuo L.; Rothenberg M.E.: Gastrointestinal eosinophilia. Immunol Allergy Clin North Am, 2007 Aug;27(3):443-55.
Simson L.; Ellyard J.I.; Dent L.A.; Matthaei K.I.; Rothenberg M.E.; Foster P.S.; Smyth M.J.; Parish C.R.: Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance. J Immunol, 2007 Apr 1;178:4222-9.
Rothenberg M.E.; Cohen M.B.: An eosinophil hypothesis for functional dyspepsia. Clin Gastroenterol Hepatol, 2007 Oct;5:1147-8.
Rothenberg M.E.: Eosinophils in the new millennium. J Allergy Clin Immunol, 2007 Jun;119:1321-2.
Munitz A.; Bachelet I.; Finkelman F.D.; Rothenberg M.E.; Levi-Schaffer F.: CD48 is critically involved in allergic eosinophilic airway inflammation. Am J Respir Crit Care Med, 2007 May 1;175:911-8.
Mishra A.; Wang M.; Schlotman J.; Nikolaidis N.M.; DeBrosse C.W.; Karow M.L.; Rothenberg M.E.: Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. Am J Physiol Lung Cell Mol Physiol, 2007 Aug;293:L305-13.
Mishra A.; Schlotman J.; Wang M.; Rothenberg M.E.: Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice. J Leukoc Biol 2007 Apr;81:916-24.
McGraw D.W.; Elwing J.M.; Fogel K.M.; Wang W.C.; Glinka C.B.; Mihlbachler K.A.; Rothenberg M.E.; Liggett S.B.: Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation. J Clin Invest 2007 May;117:1391-8.
Furuta G.T.; Liacouras C.A.; Collins M.H.; Gupta S.K.; Justinich C.; Putnam P.E.; Bonis P.; Hassall E.; Straumann A.; Rothenberg M.E.: Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology, 2007 Oct;133:1342-63.
Bullock J.Z.; Villanueva J.M.; Blanchard C.; Filipovich A.H.; Putnam P.E.; Collins M.H.; Risma K.A.; Akers R.M.; Kirby C.L.; Buckmeier B.K.; Assa'ad A.H.; Hogan S.P.; Rothenberg M.E.: Interplay of adaptive th2 immunity with eotaxin-3/c-C chemokine receptor 3 in eosinophilic esophagitis. J Pediatr Gastroenterol Nutr, 2007 Jul;45:22-31.
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2006
Zimmermann N.; Rothenberg M.E.: The arginine-arginase balance in asthma and lung inflammation. Eur J Pharmacol, 2006 Mar 8;533:253-62.
Yang M.; Rangasamy D.; Matthaei K.I.; Frew A.J.; Zimmmermann N.; Mahalingam S.; Webb D.C.; Tremethick D.J.; Thompson P.J.; Hogan S.P.; Rothenberg M.E.; Cowden W.B.; Foster P.S.: Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness. J Immunol, 2006 Oct 15;177:5595-603.
Yamada Y.; Rothenberg M.E.; Lee A.W.; Akei H.S.; Brandt E.B.; Williams D.A.; Cancelas J.A.: The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease. Blood, 2006 May 15;107:4071-9.
Stein M.L.; Collins M.H.; Villanueva J.M.; Kushner J.P.; Putnam P.E.; Buckmeier B.K.; Filipovich A.H.; Assa'ad A.H.; Rothenberg M.E.: Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis. J Allergy Clin Immunol, 2006 Dec;118:1312-9.
Rothenberg M.E.; Hogan S.P.: The eosinophil. Annu Rev Immunol, 2006;24:147-74.
Rothenberg M.E.; Doepker M.P.; Lewkowich I.P.; Chiaramonte M.G.; Stringer K.F.; Finkelman F.D.; MacLeod C.L.; Ellies L.G.; Zimmermann N.: Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung. Proc Natl Acad Sci USA 2006 Oct 3;103:14895-900.
Nikolaidis N.M.; Wang T.C.; Hogan S.P.; Rothenberg M.E.: Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung. Exp Lung Res, 2006 Nov-Dec;32:483-97.
Munitz A.; Bachelet I.; Eliashar R.; Khodoun M.; Finkelman F.D.; Rothenberg M.E.; Levi-Schaffer F.: CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J Immunol, 2006 Jul 1;177:77-83.
Letuve S.; Lajoie-Kadoch S.; Audusseau S.; Rothenberg M.E.; Fiset P.O.; Ludwig M.S.; Hamid Q.: IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. J Allergy Clin Immunol, 2006 Mar;117:590-6.
Konikoff M.R.; Noel R.J.; Blanchard C.; Kirby C.; Jameson S.C.; Buckmeier B.K.; Akers R.; Cohen M.B.; Collins M.H.; Assa'ad A.H.; Aceves S.S.; Putnam P.E.; Rothenberg M.E.: A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology, 2006 Nov;131:1381-91.
Konikoff M.R.; Blanchard C.; Kirby C.; Buckmeier B.K.; Cohen M.B.; Heubi J.E.; Putnam P.E.; Rothenberg M.E.: Potential of blood eosinophils, eosinophil-derived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis. Clin Gastroenterol Hepatol, 2006 Nov;4:1328-36.
Klion A.D.; Bochner B.S.; Gleich G.J.; Nutman T.B.; Rothenberg M.E.; Simon H.U.; Wechsler M.E.; Weller P.F.; The Hypereosinophilic Syndromes Working Group: Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. J Allergy Clin Immunol, 2006 Jun;117:1292-302.
Hogan S.P.; Seidu L.; Blanchard C.; Groschwitz K.; Mishra A.; Karow M.L.; Ahrens R.; Artis D.; Murphy A.J.; Valenzuela D.M.; Yancopoulos G.D.; Rothenberg M.E.: Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. J Allergy Clin Immunol, 2006 Jul;118:257-68.
Hogan S.P.; Rothenberg M.E.: Eosinophil Function in Eosinophil-associated Gastrointestinal Disorders. Curr Allergy Asthma Rep, 2006 Feb;6:65-71.
Fulkerson P.C.; Fischetti C.A.; Rothenberg M.E.: Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling. Am J Pathol, 2006 Dec;169:2117-26.
Fulkerson P.C.; Fischetti C.A.; McBride M.L.; Hassman L.M.; Hogan S.P.; Rothenberg M.E.: A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proc Natl Acad Sci USA, 2006 Oct 31;103:16418-23.
Fulkerson P.C.; Fischetti C.A.; Hassman L.M.; Nikolaidis N.M.; Rothenberg M.E.: Persistent effects induced by IL-13 in the lung. Am J Respir Cell Mol Biol, 2006 Sep;35:337-46.
Forbes E.; Hulett M.; Ahrens R.; Wagner N.; Smart V.; Matthaei K.I.; Brandt E.B.; Dent L.A.; Rothenberg M.E.; Tang M.; Foster P.S.; Hogan S.P.: ICAM-1-dependent pathways regulate colonic eosinophilic inflammation. J Leukoc Biol, 2006 Aug;80:330-41.
Dixon H.; Blanchard C.; Deschoolmeester M.L.; Yuill N.C.; Christie J.W.; Rothenberg M.E.; Else K.J.: The role of Th2 cytokines, chemokines and parasite products in eosinophil recruitment to the gastrointestinal mucosa during helminth infection. Eur J Immunol, 2006 Jul;36:1753-63.
DeBrosse C.W.; Case J.W.; Putnam P.E.; Collins M.H.; Rothenberg M.E.: Quantity and distribution of eosinophils in the gastrointestinal tract of children. Pediatr Dev Pathol, 2006 May-Jun;9:210-8.
Brandt E.B.; Zimmermann N.; Muntel E.E.; Yamada Y.; Pope S.M.; Mishra A.; Hogan S.P.; Rothenberg M.E.: The alpha4bbeta7-integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine. Clin Exp Allergy, 2006 Apr;36:543-53.
Brandt E.B.; Scribner T.A.; Akei H.S.; Rothenberg M.E.: Experimental gastrointestinal allergy enhances pulmonary responses to specific and unrelated allergens. J Allergy Clin Immunol, 2006 Aug;118:420-7.
Blanchard C.; Wang N.; Stringer K.F.; Mishra A.; Fulkerson P.C.; Abonia J.P.; Jameson S.C.; Kirby C.; Konikoff M.R.; Collins M.H.; Cohen M.B.; Akers R.; Hogan S.P.; Assa'ad A.H.; Putnam P.E.; Aronow B.J.; Rothenberg M.E.: Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest, 2006 Feb;116:536-47.
Blanchard C.; Wang N.; Rothenberg M.E.: Eosinophilic esophagitis: pathogenesis, genetics, and therapy. J Allergy Clin Immunol, 2006 Nov;118:1054-9.
Akei H.S.; Brandt E.B.; Mishra A.; Strait R.T.; Finkelman F.D.; Warrier M.R.; Hershey G.K.; Blanchard C.; Rothenberg M.E.: Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses. J Allergy Clin Immunol, 2006 Jul;118:62-9.
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2005
Zimmermann N.; Doepker M.P.; Witte D.P.; Stringer K.F.; Fulkerson P.C.; Pope S.M.; Brandt E.B.; Mishra A.; King N.E.; Nikolaidis N.M.; Wills-Karp M.; Finkelman F.D.; Rothenberg M.E.: Expression and regulation of small proline-rich protein 2 in allergic inflammation. Am J Respir Cell Mol Biol, 2005 May;32:428-35.
Zimmermann N.; Colyer J.L.; Koch L.E.; Rothenberg M.E.: Analysis of the CCR3 promoter reveals a regulatory region in exon 1 that binds GATA-1. BMC Immunol, 2005 Apr 4;6:7.
Xanthakos S.A.; Schwimmer J.B.; Melin-Aldana H.; Rothenberg M.E.; Witte D.P.; Cohen M.B.: Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. J Pediatr Gastroenterol Nutr, 2005 Jul;41:16-22.
Sutton S.A.; Assa'ad A.H.; Rothenberg M.E.: Anti-IL-5 and hypereosinophilic syndromes. Clin Immunol, 2005 Apr;115:51-60.
Spergel J.; Rothenberg M.E.; Fogg M.: Eliminating eosinophilic esophagitis. Clin Immunol, 2005 May;115:131-2.
Simons J.E.; Rothenberg M.E.; Lawrence R.A.: Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection. Eur J Immunol, 2005 Jan;35:189-97.
Prescott V.E.; Campbell P.M.; Moore A.; Mattes J.; Rothenberg M.E.; Foster P.S.; Higgins T.J.; Hogan S.P.: Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. J Agric Food Chem, 2005 Nov 16;53:9023-30.
Pope S.M.; Zimmermann N.; Stringer K.F.; Karow M.L.; Rothenberg M.E.: The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia. J Immunol, 2005 Oct 15;175:5341-50.
Pope S.M.; Fulkerson P.C.; Blanchard C.; Akei H.S.; Nikolaidis N.M.; Zimmermann N.; Molkentin J.D.; Rothenberg M.E.: Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J Biol Chem, 2005 Apr 8;280:13952-61.
Ort T.; Arjona A.A.; MacDougall J.R.; Nelson P.J.; Rothenberg M.E.; Wu F.; Eisen A.; Halvorsen Y.D.: Recombinant human FIZZ3/resistin stimulates lipolysis in cultured human adipocytes, mouse adipose explants, and normal mice. Endocrinology, 2005 May;146(5):2200-9.
Noel R.J.; Rothenberg M.E.: Eosinophilic esophagitis. Curr Opin Pediatr, 2005 Dec;17:690-4.
Fulkerson P.C.; Zhu H.; Williams D.A.; Zimmermann N.; Rothenberg M.E.: CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism. Blood, 2005 Jul 15;106:436-43.
Fulkerson P.C.; Rothenberg M.E.; Hogan S.P.: Building a better mouse model: experimental models of chronic asthma. Clin Exp Allergy, 2005 Oct;35:1251-3.
Finkelman F.D.; Yang M.; Perkins C.; Schleifer K.; Sproles A.; Santeliz J.; Bernstein J.A.; Rothenberg M.E.; Morris S.C.; Wills-Karp M.: Suppressive effect of IL-4 on IL-13-induced genes in mouse lung. J Immunol, 2005 Apr 15;174:4630-8.
Finkelman F.D.; Rothenberg M.E.; Brandt E.B.; Morris S.C.; Strait R.T.: Molecular mechanisms of anaphylaxis: lessons from studies with murine models. J Allergy Clin Immunol, 2005 Mar;115:449-57; quiz 458.
Blanchard C.; Mishra A.; Saito-Akei H.; Monk P.; Anderson I.; Rothenberg M.E.: Inhibition of human interleukin-13-induced respiratory and oesophageal inflammation by anti-human-interleukin-13 antibody (CAT-354). Clin Exp Allergy 2005 Aug;35:1096-103.
Akei H.S.; Mishra A.; Blanchard C.; Rothenberg M.E.: Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice. Gastroenterology, 2005 Sep;129:985-94.
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2004
Zimmermann N.; Mishra A.; King N.E.; Fulkerson P.C.; Doepker M.P.; Nikolaidis N.M.; Kindinger L.E.; Moulton E.A.; Aronow B.J.; Rothenberg M.E.: Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways. J Immunol, 2004 Feb 1;172:1815-24.
Wan H.; Kaestner K.H.; Ang S.L.; Ikegami M.; Finkelman F.D.; Stahlman M.T.; Fulkerson P.C.; Rothenberg M.E.; Whitsett J.A.: Foxa2 regulates alveolarization and goblet cell hyperplasia. Development, 2004 Feb;131:953-64.
Rothenberg M. E.: Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol, 2004 Jan;113:11-28; quiz 29.
Rothenberg M.E.: VEGF obstructs the lungs. Nat Med, 2004 Oct;10:1041-2.
Noel R.J.; Putnam P.E.; Rothenberg M.E.: Eosinophilic esophagitis. N Engl J Med, 2004 Aug 26;351:940-1.
Noel R.J.; Putnam P.E.; Collins M.H.; Assa'ad A.H.; Guajardo J.R.; Jameson S.C.; Rothenberg M.E.: Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. Clin Gastroenterol Hepatol, 2004 Jul;2:568-75.
King N. E.; Zimmermann N.; Pope S.M.; Fulkerson P.C.; Nikolaidis N.M.; Mishra A.; Witte D.P.; Rothenberg M.E.: Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma. Am J Respir Cell Mol Biol, 2004 Sep;31:257-65.
King N.E.; Rothenberg M.E.; Zimmermann N.: Arginine in asthma and lung inflammation. J Nutr, 2004 Oct;134:2830S-2836S; discussion 2853S.
Hogan S.P.; Rothenberg M.E.; Forbes E.; Smart V.E.; Matthaei K.I.; Foster P.S.: Chemokines in eosinophil-associated gastrointestinal disorders. Curr Allergy Asthma Rep, 2004 Jan;4:74-82.
Hogan S.P.; Rothenberg M.E.: Review article: The eosinophil as a therapeutic target in gastrointestinal disease. Aliment Pharmacol Ther, 2004 Dec;20:1231-40.
Garrett J.K.; Jameson S.C.; Thomson B.; Collins M.H.; Wagoner L.E.; Freese D.K.; Beck L.A.; Boyce J.A.; Filipovich A.H.; Villanueva J.M.; Sutton S.A.; Assa'ad A.H.; Rothenberg M.E.: Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes. J Allergy Clin Immunol, 2004 Jan;113:115-9.
Fulkerson P.C.; Zimmermann N.; Hassman L.M.; Finkelman F.D.; Rothenberg M.E.: Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma. J Immunol, 2004 Dec; 173:7565-74.
Fulkerson P.C.; Zimmermann N.; Brandt E.B.; Muntel E.E.; Doepker M.P.; Kavanaugh J.L.; Mishra A.; Witte D.P.; Zhang H.; Farber J.M.; Yang M.; Foster P.S.; Rothenberg M.E.: Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9). Proc Natl Acad Sci USA, 2004 Feb; 101:1987-92.
Forbes E.; Smart V.E.; D'Aprile A.; Henry P.; Yang M.; Matthaei K.I.; Rothenberg M.E.; Foster P.S.; Hogan S.P.: T helper-2 immunity regulates bronchial hyperresponsiveness in eosinophil-associated gastrointestinal disease in mice. Gastroenterology, 2004 Jul;127:105-18.
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