Recent Publications for Jodie Y. Duffy, PhD
J.M. Pearl, D.M. Plank, K.M. McLean, C.J. Wagner, J.Y. Duffy. 2009. Glucocorticoids improve calcium handling in isolated cardiac myocytes after ischemia and reperfusion. Annals of Thoracic Surgery (In press).
O. Petrucci, K.A. Vilarinho, R.S. Baker, J. Vassallo, A.A. Schenka, J.Y. Duffy, P.P.de Oliveira, R.W. Vieira. 2009. Early changes in contractility indexes and fibrosis in two minimally invasive congestive heart failure models. European Journal of Cardiothoracic Surgery (In press).
E.A. Heeb, R.S. Baker, C. Lam, M. Basu, W. Lubbers, J.Y. Duffy, P. Eghtesady. 2009. Role of natriuretic peptides in cGMP production in fetal cardiac bypass. Annals of Thoracic Surgery 87:841-847.
J.Y. Duffy, K.M. McLean, J.M. Lyons, A.J. Czaikowski, C.J. Wagner, J.M. Pearl. 2009. Modulation of nuclear factor-kappaB improves cardiac dysfunction associated with cardiopulmonary bypass and deep hypothermic circulatory arrest. Critical Care Medicine 37:577-583.
J.M. Pearl, J.Y. Duffy, K.M. McLean. Pediatric Myocardial Protection. In: D.S. Wheeler, H.R. Wong, T.P. Shanley. Pediatric Critical Care Medicine: Basic Science and Clinical Evidence. Springer-Verlag, London, 2009.
P.K. Pandalai, K.M. McLean, C.F. Bulcao, J.Y. Duffy, K.M. D’Souza, W.H. Merrill, J.M. Pearl, S.A. Akhter. 2008. Acute β-blockade prevents myocardial β-adrenergic receptor desensitization and preserves early ventricular function after brain death. Journal of Thoracic and Cardiovascular Surgery 135:792-798.
K.M. McLean, P.K. Pandalai, J.M. Pearl, S.A. Akhter, J.M. Lyons, C.F. Bulcao, C.J. Wagner, J.Y. Duffy. 2007. Beta-adrenergic receptor antagonism prior to brain death preserves myocardial function in a porcine model. Journal of Heart and Lung Transplantation 26:522-528.
K.M. McLean, J.Y. Duffy, P.K. Pandalai, J.M. Lyons, C.F. Bulcao, C.J. Wagner, S.A. Akhter, J.M. Pearl. 2007. Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death. Journal of Heart and Lung Transplantation 26:78-84.
J.M. Lyons, J.P. Pearl, K.M. McLean, S.A. Akhter, C.J. Wagner, P.K. Pandalai, J.Y. Duffy. 2005. Glucocorticoid administration reduces cardiac dysfunction after brain death in pigs. Journal of Heart and Lung Transplantation 24:2249-2256.
R.K. Kaiser, J.M. Lyons, J.Y. Duffy, C.J. Wagner, K.M. McLean, T.P. O’Neill, J.M. Pearl, J.D. Molkentin. 2005. Inhibition of p38 reduces myocardial infarction in the mouse but not the pig after ischemia-reperfusion. American Journal of Physiology, Heart and Circulation Physiology 289:H2477-2451
P.K. Pandalai, J.M. Lyons, K.M. McLean, J.M. Pearl, J.Y. Duffy, C.J. Wagner, W.H. Merrill, S.A. Akhter. 2005. Role of β-adrenergic receptor kinase in myocardial dysfunction following brain death. Journal of Thoracic and Cardiovascular Surgery 130:1183-1189.
J.Y. Duffy, S.M. Schwartz, J.M. Lyons, J.H. Bell, C.J. Wagner, B. Zingarelli, J.M. Pearl. 2005. Calpain inhibition decreases endothelin-1 levels and pulmonary hypertension after cardiopulmonary bypass and deep hypothermic circulatory arrest. Critical Care Medicine 33:623-628.
Recent Presentations and Abstracts
J.Y. Duffy, R.S. Baker, M. Basu, C. Reed, E.A. Heeb, P. Eghtesady. 2008. Myocardial contractile dysfunction is associated with fetal cardiac bypass in a sheep model. American Heart Association Scientific Sessions. New Orleans, LA. Circulation 118:S543.
C.F. Bulcao, K.M. D’Souza, R. Malhotra, M. Staron, P.K. Pandalai, J.Y. Duffy, S. A. Akhter. 2008. Activation of inflammatory and apoptotic pathways in human donor heart dysfunction. American Heart Association Scientific Sessions. New Orleans, LA. Circulation 118:S1015.
J.Y. Duffy, R.C. Doerning, E.R. Schoettmer, J.M. Pearl. 2008. Calpain inhibition regulates endothelin-1 and nitric oxide during simulated ischemia and reperfusion of isolated cardiomyocytes. International Society of Heart Research Annual Meeting. Cincinnati, OH.
J.Y. Duffy, C.J. Wagner, J.M. Pearl. 2008. Calpain Inhibition reduces nuclear factor-kappaB activity and apoptosis markers after cardiopulmonary bypass in neonatal piglets. American Heart Association. The Scientific Basis of Heart Failure in Children. Estes Park, CO.
H. Sideek, P. Eghtesady, K.E. Clark, C.J. Wagner, J.Y. Duffy. 2008. Serum collected during and after fetal sheep cardiopulmonary bypass stimulates nitric oxide and endothelin-1 production by umbilical vein endothelial cells. Society of Gynecological Investigation Annual Meeting. San Diego, CA.
J.M. Pearl, K.M. McLean, B. Zingarelli, H.R Wong, J.Y Duffy. 2008. Epigallocatechin-3-gallate moderates nitric oxide production during ischemia and reperfusion of cardiomyocytes. Society of Thoracic Surgeons Annual Meeting. Fort Lauderdale, FL.
J.M. Pearl, D.M. Plank, K.M. McLean, J.Y. Duffy. 2008. Glucocorticoid administration improves calcium handling by cardiomyocytes after ischemia and reperfusion. Society of Thoracic Surgeons Annual Meeting. Fort Lauderdale, FL.
J.Y. Duffy, K.M. McLean, C.J. Wagner, J.M. Pearl. 2007. Alleviating pulmonary hypertension with calpain inhibition. Pulmonary Hypertension Workgroup. Cincinnati Children’s Hospital Medical Center.
K.M. McLean, P.K. Pandalai, J.M. Pearl, S.A. Akhter, C.F. Bulcao, C.J. Wagner, J.Y. Duffy. 2006. Beta-adrenergic receptor antagonism prior to brain death preserves myocardial function in a porcine model. American College of Surgeons Annual Meeting.
R.A. Doerning, K.M. McLean, J.M. Pearl, C.J. Wagner, J.Y. Duffy. 2006. Calpain Inhibition reduces cardiomyocyte ischemia and reperfusion injury. American Association for the Advancement of Science Annual Meeting, St. Louis, MO.
K.M. McLean, J.M. Lyons, J.Y. Duffy, S.A. Akhter, C.J. Wagner, J.M. Pearl. 2005. Glucocorticoids prior to brain death shift the balance between pro- and anti-inflammatory mediators in the myocardium. The International Society for Heart and
Lung Transplantation 25th Annual Meeting and Scientific Sessions, Philadelphia, PA, Journal of Heart and Lung Transplantation 24:S120.
P.K. Pandalia, J.M. Lyons, J.Y. Duffy, K.M. McLean, C.J. Wagner, J.M. Pearl, W.M. Merrill, S.A. Akhter. 2005. The role of the beta-adrenergic receptor kinase in myocardial dysfunction following brain death. The International Society for Heart and Lung Transplantation 25th Annual Meeting and Scientific Sessions, Philadelphia, PA, Journal of Heart and Lung Transplantation 24:S142.
K.M. McLean, J.M. Pearl, S. Johnstone, C.J. Wagner, J.L. McNamara, J.Y. Duffy. 2005. Calpain inhibition alleviates troponin I degradation after hypoxia and reoxygenation on cardiopulmonary bypass in pigs. American Heart Association Scientific Sessions, Dallas, TX.
J.Y. Duffy, D.M. Plank, S.M. Schwartz, K.M. McLean, J.M. Pearl. 2005. Glucocorticoid administration improves calcium handling by cardiomyocytes after ischemia and reperfusion. American Heart Association Heart Failure Symposium. Keystone, CO.
J.Y. Duffy, J.M. Lyons, C.J. Wagner, K.M. McLean, J.M. Pearl. 2005. Calpain inhibition prevents both acute myocardial ischemia-reperfusion injury and apoptosis in neonatal piglets. University of Cincinnati Department of Surgery Research Retreat. Cincinnati, Ohio.
K.M. McLean, J.M. Pearl, S. Johnstone, C.J. Wagner, J.L. McNamara, J.Y. Duffy. 2005. Calpain inhibition alleviates troponin I degradation after hypoxia and reoxygenation on cardiopulmonary bypass in pigs. American Heart Association Heart Failure Symposium. Keystone, CO.
P.K. Pandalai, J.M. Lyons, J.Y. Duffy, K.M. McLean, C.J. Wagner, J.M. Pearl, W.H. Merrill, S.A. Akhter. 2005. The role of β-adrenergic receptor kinase in myocardial dysfunction following brain death. The Journal of Heart and Lung Transplantation 24:S120.
K.M. McLean, J.M. Lyons, J.Y. Duffy, S.A. Akhter, C.J. Wagner, J.M. Pearl. 2005. Glucocorticoids prior to brain death shift the balance between pro- and anti-inflammatory mediators in the myocardium. The Journal of Heart and Lung Transplantation 24:S142.
