Critical Care

Derek Wheeler, MD, FAAP

Title

Attending Physician

Appointment

Assistant Professor of Clinical Pediatrics

Email

derek.wheeler@cchmc.org

Phone

513-636-4259 or513-636-1570

Fax

513-636-4267

Credentials

MD: Indiana University School of Medicine, Indianapolis, IN, 1994

Intern: Department of Pediatrics, Naval Medical Center, San Diego, CA, 1994-1995

Residency: Department of Pediatrics, Naval Medical Center, San Diego, CA, 1995-1997

Fellowship: Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2000-2003

Certification: Diplomate, National Board of Medical Examiners, 1995; Diplomate, American Board of Pediatrics, 1997, 2004; Diplomate, American Board of Pediatrics: Sub-Board of Pediatric Critical Care Medicine, 2004

Awards and Honors

United States Health Professions Scholarship Program, 1993
Society of Critical Care Medicine, Education Scholarship Award, 2002
Society of Critical Care Medicine, Specialty Award: Pediatrics, 2004
Society of Critical Care Medicine, Specialty Award: Pharmacology, 2004

Research

Stress preconditioning
The innate immune response in critical illness
Vascular Biology of sepsis and acute lung injury

Research Grants and Contracts

The immunomodulatory effects of extracellular Hsp 70, National Institutes of Health, Principle Investigator, 4/01/2006-4/01/2011.

Publications, Most Recent

Mehta R, Fisher LE, Segeleon JE, Pearson-Shaver AL, Wheeler DS. Acute rhabdomyolysis complicating status asthmaticus in children: Case series and review.Pediatr Emerg Care 2006; 22:587-591

Wheeler DS, Mehta R, Fisher LE Jr, Segeleon JE, Pearson-Shaver AL. A tale of two sisters.Pediatr Emerg Care 2006; 22:197-200

Eghtesady P, Nelson D, Schwartz SM, Wheeler D, Pearl JM, Cripe LH, Manning PB. Heparin-induced thrombocytopenia complicating support by the Berlin heart.ASAIO J 2005; 51:820-825

Wheeler DS, Fisher, Jr LE, Catravas JD, Jacobs BR, Carcillo JA, Wong HR. Extracellular HSP 70 levels in children with septic shock.Pediatr Crit Care Med 2005; 6:308-311

Wheeler DS, Jacobs BR, Kenreigh CA, Bean JA, Hutson TK, Brilli RJ. Theophylline versus terbutaline in treating critically ill children with status asthmaticus: A prospective, randomized, controlled trial.Pediatr Crit Care Med 2005; 6:142-147

Wheeler DS. Phospholipase A2 and acute lung ingury: it's just not that simple.Crit Care Med 2005; 33:904-905

Wheeler DS, Catravas JD, Odoms K, Denenberg AG, Malhotra V, Wong HR. Epigallocatechin-3-gallate (EGCG), a green tea-derived polyphenol, inhibits IL-1B-dependent proinflammatory signal transduction in cultured respiratory epithelial cells.J Nutrition 2004; 134:1039-1044

Wheeler DS, Wheeler WJ. The medicinal chemistry of tea.Drug Dev Res 2004;61:45-65

Wheeler DS, Maxwell JM, Poss WB. Surgical ligation of a residual patent arterial duct following failed transcatheter coil occlusion.Cardiology of the Young 2003;13:574-575

Wheeler DS, Vaux KK, Ponaman ML, Poss WB. The safe and effective use of propofol sedation in children undergoing diagnostic and therapeutic procedures: experience in a Pediatric ICU and review of the literature.PediatrEmerg Care 2003;19:385-392.

Wheeler DS, Kooy N. A formidable challenge: The diagnosis and management of viral myocarditis in children.Crit Care Clin North Am 2003;19:365-391.

Wheeler DS, Bonny AE, Ruddy RM, Jacobs BR. Late onset respiratory distress after inhalation of laundry detergent.Pediatr Pulmonol, 2003;35:323-5.

Wheeler DS. Poss WB. Mass casualty management in a changing world. Pediatr Ann 2003;32:98-105.

Wheeler DS, Clapp CR, Poss WB. Training in pediatric critical care medicine: a survey of pediatric residency training programs.Pediatr Emerg Care 2003;19:1-5.

Wheeler DS, Dunsmore KD, Wong HR. Intracellular delivery of HSP70 using the HIV-1 tat protein transduction domain.Biochem Biophys Res Comm, 2003;301:54-59.

Chen PC, Wheeler DS, Malhotra V, Odoms K, Denenberg AG, Wong HR. A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits Ik B kinase activation and IL-8 gene expression in respiratory epithelium.Inflammation, 2002;26:233-241.

Wheeler DS. Emergency Medical Services for Children: Prehospital evaluation and care of the special needs and technology-dependent child. Emerg Med Serv 2002;31:45-60.

Wheeler DS, Poss WB. Transport of the mechanically ventilated pediatric patient.Resp Clin North Am 2002;8:83-104.

Wheeler DS, Wong HR. The impact of molecular biology on the practice of pediatric critical care medicine.Pediatr Crit Care 2001;2:299-310.

Wheeler DS, Jenkins RA, Poss WB. A randomized, blinded comparison of chloral hydrate and midazolam sedation in children undergoing echocardiography.Clin Pediatr (Phila) 2001;40:381-387.

Wheeler DS, Kiefer ML, Poss WB. Pediatric emergency preparedness in the office.Am Fam Physician 2000;61:3333-3342.

Wheeler DS, Clapp CR, Ponaman ML, McEachren H, Poss WB. Isoflurane therapy for status astmaticus in children.Pediatr Crit Care 2000;1:55-59.

Fazio RF, Wheeler DS, Poss WB. Resident training in pediatric critical care transport medicine: a survey of pediatric residency programs.Pediatr Emerg Care 2000;16:166-169.

Wheeler DS, Vaux KK, Starr SR, Poss WB. The pediatric critical experience at Naval Hospital Guam: suggestions for critical care training during residency.Mil Med 2000;165:441-444.

Wheeler DS, Vaux KK, Tam DA. Use of gabapentin in the treatment of childhood reflex sympathetic dystrophy.Pediatr Neurol 2000; 22:220-221.

Wheeler DS. Emergency medical services for children: a general pediatrician's prespective. Curr Prob Pediatr 1999;29:221-248.

Krumwiede G, Gaston B. Braided bronchus: a previously undescribed airway anomaly.Year Book of Diagnostic Radiology 1999;213-214.

Wheeler DS, Sperring JL, Vaux KK, Poss WB. Development of a pediatric critical care transport team: experience at a military medical center.Mil Med 1999;164:188-93.

Wheeler DS, Vazquez WD, Vaux KK, Poss WB. Streptococcal pyomyositis: case report and review.Pediatr Emerg Care 1998;14:411-412.

Wheeler DS. Poss WB, Cocalis M, Krumwiede G, Gaston B. Braided bronchus: a previously undescribed airway anomaly.Pediatr Pulmonol 1998;25:348-351.

Wheeler DS, Shope TR. Depressed skull fracture in a 7-month-old infant who fell from bed.Pediatrics 1997;100:1033-1034.