Nadean L. Brown, PhD
Appointment
Associate Professor, University of Cincinnati College of Medicine
Email
nadean.brown@cchmc.org
Phone
513-636-1963
Fax
513-636-4317
Credentials
PhD: Cellular and Molecular Biology, University of Wisconsin, Madison, WI 1994
Postdoctoral Fellowship: Department of Biology, University of Michigan 1995-1996
Postdoctoral Fellowship: Departments of Human Genetics and Internal Medicine, University of Michigan 1996-1999
Assistant Professor: Division of Developmental Systems Biology, Department of Pediatrics, Northwestern University Medical School, Chicago, IL, 2000-2002
Awards and Honors
- NRSA Postdoctoral Research Fellowship
- NSF Postdoctoral Fellowship
- Howard Hughes Medical Institute Postdoctoral Fellowship
- Cold Spring Harbor Medical Course, "Molecular Embryology of the Mouse" Participant
Research
Visit the Brown Lab Site.
Research Grants and Contracts
Active:
NIH EY13612 (NL Brown, PI): Investigation of Mammlian Retinal Neuron Development. 8/2009-7/2013
NIH EY18097 (NL Brown, PI): Cell-Cell Signaling during Mammalian Eye Formation 4/2008-3/2012
Past:
Grant-In-Aid from The Glaucoma Foundation (NL Brown, PI): In Vivo Investigation of Optic Nerve Formation and Connectivity within the Mouse Brain 1/2007-12/2007
NIH EY13612 (NL Brown, PI): Investigation of Mammalian Retinal Neuron Development 8/2001-8/2008
Publications, Most Recent
Nadean Brown's publications as listed by PubMed
Hufnagel RB, Le TT, Riesenberg AL, Brown NL. Neurog2 controls the leading edge of neurogenesis in the mammalian retina. Developmental Biology 2010; In Press.
Brzezinski JA, Rao S, Konheim A, Saul S, Lang RA, Brown NL and Glaser T. Retinal ganglion cells are required for normal vascular development and hyaloid regression. Developmental Biology 2010; In revision.
Brown N.L. “Ganglion cell development: early steps/fate" in Encyclopedia of the Eye. Section Editor, Tom Reh. Oxford: Elsevier. May, 2010.
Riesenberg AN, Liu Z, Kopan R, Brown NL. Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. Journal of Neuroscience 2009;29(41): 12865-77.
Riesenberg AN, Le TT, Willardson MI, Blackburn DC, Vetter ML, Brown NL. Pax6 regulation of Math5 during mouse retinal neurogenesis.Genesis 2009;47(3):175-187.
Le TT, Conley K, Brown NL. Jagged1 is necessary for normal mouse lens development.Developmental Biology 2009;328(1):118-126.
Willardson MI, Suli A, Pan Y, Marsh-Armstrong N, El-Hodiri H, Chen CB, Moore KB, Brown NL, Vetter ML. Temporal regulation of Ath5 gene expression during eye development.Developmental Biology 2009;326(2):471-481.
Fuhrmann S, Riesenberg AN, Mathiesen AM, Brown EC, Vetter ML, Brown NL. Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina.Invest. Ophth. Vis Sci 2009;50(1):432-440.
Rowan S, Conley K, Le TT, Donner AL, Maas RL, Brown, NL. Notch signaling is required for mouse lens growth and differentiation.Developmental Biology 2008; 321(1):111-122.
Blackburn DC*, Conley K*, Platchetzki D, Kempler K, Battelle BA, Brown NL. Isolation and expression of Pax6 and atonal homologues in the American Horseshoe Crab, Limulus polyphemus.Developmental Dynamics 2008;237(8):2209-2219. *Co-First Authors
Hufnagel RB, Riesenberg AN, Saul SM, Brown NL. Conserved regulation between Math5 and Math1 as revealed by Math5-GFP transgenes. Molecular and Cellular Neuroscience 2007;36(4):435-488.
Professional Organization Memberships
Teaching
I contribute lectures to the Intro to the Developmental Biology (MDB program), Advanced Developmental Biology (MDB program) and Neurodevelopment (Neuroscience Program) graduate courses.
Special Interests
Developmental genetics of mammalian lens and retinal formation
Invited Research Presentations
2009, Department of Ophthalmology, Washington University School of Medicine, St.Louis, MO
2009, Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI
2009, Department of Ophthalmology and Vision Sciences, University of Louisville, Louisville, KY
2009, Department of Ophthalmology, Ottawa Health Research Institute, Ottawa, Canada
2009, Assoc. for Research in Vision and Ophthalmology Meeting, Ft. Lauderdale, FL
2008, Visual System Development Gordon Research Conference, Newport, RI
2008, Midwest Society for Developmental Biology Meeting, Iowa City, IA
2008, Assoc. for Research in Vision and Ophthalmology Meeting, Ft. Lauderdale, FL
