Representative Publications
Guasch G, Schober M, Pasolli A, Conn E, Polak L, Fuchs E. Loss of TGFβ signalling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell 2007;12:313-27.
*Li J, *Greco V, *Guasch G, Fuchs E, Mombaert P. Mice cloned from skin cells. Proc Natl Acad Sci USA 2007;104: 2738-43. (* contributed equally to this work).
Lowry W, Blanpain C, Nowak J, Guasch G, Lewis L, Fuchs E. Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells. Genes & Dev 2005;13:1596-611.
Guasch G, Fuchs E. Mice in the world of stem cell biology. Nature Genetics 2005;37(11):1201-6. [review]
Tumbar T, Guasch G, Greco V, Blanpain C, Lowry W, Rendl M, Fuchs E. Defining the epithelial stem cell niche in skin. Science 2004;303:359-63.
Fuchs E, Tumbar T, Guasch G. Socializing with the neighbors: stem cells and their niche. Cell 2004;116: 769-78. [review]
Guasch G, Delaval B, Arnoulet C, Xie MJ, Xerri L, Sainty D, Birnbaum D, Pebusque MJ. FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice. Blood 2004;103:309-12.
Guasch G, Popovici C, Chaffanet M, Mugneret F, Pontarotti P, Birnbaum D., Pébusque M.J. Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem cell myeloproliferative disorder with t(8;19)(p12;q13.3). Blood 2003;101:286-8.
Guasch G, Ollendorff V, Borg JP, Birnbaum D, Pébusque M-J. 8p12 stem cell myeloproliferative disorder: the FOP-Fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-Kinase/AKT/mTOR pathways. Mol Cell Biol 2001;21:8129-42.
