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Related Publications

Lin, X (2005), Wnt signaling and transcriptional regulation, In: Gene Expression and Regulation (ed. J. Ma), a Current Scientific Frontiers Book, Higher Education Press & Springer , in press.

Tao Q, Yokota C, Puck H, Kofron M, Birsoy B, Yan D, Asashima M, Wylie CC, Lin X, and Heasman J (2005) Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos.  Cell, 120(6): 857-871. 

Han, C and Lin X (2005) Shifted from Wnt to Hh signaling pathways. Molecular Cell, 17(3),321-2.

Han C, Yan D, Belenkaya T, and Lin, X (2005) Drosophila Glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development 132:667-79. 

Lin X (2004) Functions of Heparan Sulfate Proteoglycans in cell signaling during development. Development 131, 6009-21.

Belenkaya T, Han C, Yan D, Opoka RJ, Khodoun M, Liu H, and Lin X (2004) Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis and is controlled by glypican members of heparan sulfate proteoglycans. Cell, 119(2): 231-44.

Han C, Belenkaya T, Khodoun M, Tauchi M, Lin X, and Lin X (2004) Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development 131, 1563-75.

Han C, Belenkaya T, Wang B, and Lin X (2004) Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin independent process. Development 131, 601-11.

Lin X and Perrimon N (2003) Developmental Roles of Heparan Sulfate Proteoglycans in Drosophila. Glycoconjugate 19, 363-368.

Belenkaya T, Han C, Standley H, Lin X, Houston D, Heasman J (2002) Pygopus encodes a nuclear protein essential for Wingless/Wnt signaling. Development 129, 4089-4101.

Li X R Li X Lin, and MX Guan, (2002) Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12 S rRNA A1555G mutation. J Biol Chem, 277(30), 27256-64.

Liu C, Li Y, Semenov M, Han C, Baeg, G-H, Tan Y, Zhang Z, Lin, X, and He, Xi. (2002). Control of β-catenin phosphorylation-degradation by a dual-kinase mechanism. Cell, 108(6): 837-47.

Baeg, G-H, Lin X*, Khare N Baumgartner S Perrimon N (2001) Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 128, 87-94. *Co-first author.

Lin, X and Perrimon N (2000) Role of heparan sulphate proteoglycans in cell-cell signaling in Drosophila. Matrix Biol. 19(4), 303-307.

Lin X and Perrimon N (1999) Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature 400, 281-284.

Lin X, Buff EM, Perrimon N and Michelson AM (1999) Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126, 3715-3723.

Haecker U, Lin X* and Norbert Perrimon (1997). The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124, 3565-3523. *Co-first author.