Brian Gebelein, PhD
Appointment
Assistant Professor
Email
brian.gebelein@cchmc.org
Credentials
BS: University of Wisconsin, Milwaukee, WI, 1994, Biological Sciences
PhD: Mayo Graduate School, Rochester, MN, 2000, Molecular Neuroscience
Postdoctoral Fellow: Columbia University; P.I.: Dr. Richard Mann.
Molecular mechanisms of Hox specificity in Drosophila melanogaster.
Awards and Honors
- NIH NRSA postdoctoral fellowship (GM63327); "Mechanisms of Hox specificity within the gut endoderm", 2001-2003
- Ruth Walker Award for top graduating senior in Biological Sciences, University of Wisconsin Milwaukee, 1994
Publications, Most Recent
Brian Gebelein's publications as listed by PubMed
Bessa J, Gebelein B, Pichaud F, Casares F, and Mann RS. Combinatorial control of Drosophila eye development by Eyeless, Homothorax, and Teashirt. Genes Dev., 16: 2415-2427, 2002.
Gebelein B, Culi J, Ryoo HD, Zhang W, and Mann RS. Specificity of Distalless repression and limb primordia development by abdominal Hox proteins.Developmental Cell (Cover article), 3: 487-498, 2002.
Gebelein B, McKay D, and Mann RS. Direct integration of Hox and segmentation gene inputs during Drosophila development. Nature (article), 431: 653-659, 2004.
Gebelein B and Mann RS. Compartmental modulation of abdominal Hox expression by engrailed and sloppy-paired patterns the fly ectoderm. Developmental Biology (Cover article) 308(2):593-605, 2007.
Xie B, Charlton-Perkins M, McDonald E, Gebelein B, and Cook T. Senseless functions as a molecular switch for color photoreceptor differentiation in Drosophila. Development, 134(23):4243-53, 2007.
Li-Kroeger D, Witt LM, Grimes HL, Cook TA, and Gebelein B. Hox and Senseless antagonism functions as a molecular switch to regulate EGF secretion in the Drosophila PNS. In press Developmental Cell 2008.
Gebelein B and Urrutia R. Sequence-specific transcriptional repression by KS1, a multiple zinc finger Krüppel-associated box protein.Mol. Cell. Biol., 21: 928-939, 2001.
