Vaughn G. Cleghon, PhD
Title
Associate Professor
Email
vaughn.cleghon@cchmc.org
Phone
513-803-0470
Fax
513-636-4317
Credentials
PhD: Waksman Institute of Microbiology, Rutgers, Piscataway, NJ, 1991
Postdoctoral Fellow: Dr. Deborah Morrison ABL-Basic Reasearch Program, National Cancer Institute-FCRC, Frederick, MD
Group Leader: Beatson Institute for Cancer Research, Beatson Laboratories, UK
Research
Protein kinases in development and human disease
Publications, Most Recent
Lochhead PA, Kinstrie R, Sibbet G, Rawjee, T., Morrice N, Cleghon V. GSK3β activation-loop autophosphorylation is mediated by a chaperone-dependent transitional intermediate.Molecular Cell 2006;24:627-33.
Kinstrie R, Lochhead PA, Sibbet G, Morrice N, Cleghon V. dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.Biochem J 2006;398:45-54.
Lochhead PA, Sibbet G, Morrice N, Cleghon V. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.Cell 2005;121:925-36.
