Institutes, Divisions & Centers
Developmental Biology

Today’s Discoveries, Tomorrow’s Medicines

For over three decades, researchers in the Division of Developmental Biology at Cincinnati Children’s have pioneered groundbreaking discoveries that provide insight into fundamental mechanisms of development, with an end goal of using these discoveries to advance patient care and lead to novel treatments and therapies with improved outcomes.

As a national referral site and recognized leader in clinical care and research, our mission is to enhance child health through the discovery of cellular, molecular and genetic mechanisms controlling embryonic development. We use those findings to determine how disruptions in these processes contribute to disease and inform the development of new treatments and therapies.

Research By the Numbers

Each year, our division succeeds in publishing important findings in dozens of top journals, with faculty presenting their work at national and international conferences.

Annual
Peer-Reviewed
Publications

Faculty

$10.8 M+

External Funding

Our Research

Our research spans a diverse set of disciplines and examines a multitude of cellular, molecular and systems-based questions. We are a highly collaborative group, partnering with discovery-based scientists and clinicians across various divisions—including Cardiology, Endocrinology, Gastroenterology and Hepatology, Neurology, Nephrology and Hypertension, Orthopaedics, Ophthalmology, Pulmonary Medicine and Surgery—to translate our discoveries into new medicines and treatments.

Our scientists utilize a variety of model systems and approaches to uncover mechanisms that guide organ formation at both a cellular and tissue level, elucidate the developmental basis of disease, and harness the potential of stem cells and organoids for regenerative medicine.

Our five main areas of investigation are:

Organogenesis and the developmental basis of disease
Stem cells and organoid medicine
Neurobiology
Genetics and genomics of development
Quantitative systems development

Learn More About Our Research Programs

Join Our Team

We are recruiting talent at all levels—from tenure track faculty to postdocs and students. We are dedicated to an equitable and inclusive environment and believe diverse backgrounds and perspectives fuel creativity and discovery. Contact the Developmental Biology team for more information.

2025 Top Scientific Achievement

Developmental Origins of Tracheoesophageal Birth Defects

New research maps the key genetic and developmental steps that guide separation of the trachea and esophagus, revealing how disruptions in these processes lead to life-threatening birth defects and pointing toward future regenerative therapies.

Technology Innovation and Shared Facilities

The Division of Developmental Biology is an innovation hub of Cincinnati Children’s and home to four cutting-edge core facilities that accelerate research:

Preparing Future Researchers

As the administrative home for the Development, Stem Cell & Regenerative Medicine graduate program, we are dedicated to training the next generation of diverse scientific leaders. In addition to our graduate students, we proudly mentor undergraduate students through established summer undergraduate research programs (SURF and BRIUS) that provide extensive wet-bench scientific research opportunities.